13 days in Mississippi Itinerary

13 days in Mississippi Itinerary

Created using Inspirock Mississippi trip planner

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Route & dates

13 days in Mississippi Itinerary

Start: Santiago
Fly + Drive:  20​h 15​min
1
Biloxi
— 3 nights
Drive:  4​h 15​min
2
Natchez
— 3 nights
Drive:  1​h 45​min
3
Vicksburg
— 1 night
Drive:  4​h 45​min
4
Tupelo
— 1 night
Drive:  2​h 30​min
5
Tunica
— 2 nights
Drive + Fly:  19​h 30​min
End: Santiago

3
nights
Biloxi

Biloxi ©
A busy city on the Gulf Coast, Biloxi is one of the nation's oldest communities, first settled by Europeans in 1699.
Visit Biloxi Beach and Front Beach for some beach relaxation. Popular historic sites such as Beauvoir and Biloxi Lighthouse are in your itinerary. There's lots more to do: try your luck at Beau Rivage Casino, take a leisurely stroll along Biloxi Lighthouse Pier, have some family-friendly fun at IP Casino Resort, and take in the architecture and atmosphere at Cathedral of the Nativity of the Blessed Virgin Mary.

To find photos, where to stay, traveler tips, and other tourist information, read our Biloxi trip itinerary maker app .

Santiago, Chile to Biloxi is an approximately 20.5-hour flight. The time zone changes from Chile Time (CLT) to Central Standard Time (CST), which is usually a -2 hour difference. In October in Biloxi, expect temperatures between 32°C during the day and 20°C at night. Wrap up your sightseeing on the 4th (Thu) to allow time to drive to Natchez.

Things to do in Biloxi

Casinos Fun & Games Beaches

Side Trip

Front Beach
Highlights from your plan
Hard Rock Hotel & Casino Biloxi ©
Hard Rock Hotel & Casino Biloxi
Beau Rivage Casino ©
Beau Rivage Casino
Beauvoir ©
Beauvoir

3
nights
Natchez

Natchez ©
Natchez is the county seat and only city of Adams County, Mississippi, United States. Get some cultural insight at Longwood and St. Mary Basilica. Popular historic sites such as Stanton Hall and Rosalie Mansion are in your itinerary. Spend the 7th (Sun) exploring nature at Melrose. There's lots more to do: stroll the grounds of Natchez City Cemetery, steep yourself in history at Dunleith Historic Inn, admire the striking features of Magnolia Hall, and contemplate in the serene atmosphere at First Presbyterian Church.

To find photos, reviews, where to stay, and other tourist information, read our Natchez trip itinerary planning tool .

You can drive from Biloxi to Natchez in 4.5 hours. Alternatively, you can do a combination of flight and car; or do a combination of bus, train, and car. Plan for a bit cooler nights when traveling from Biloxi in October since evenings lows in Natchez dip to 16°C. Finish your sightseeing early on the 7th (Sun) to allow enough time to drive to Vicksburg.

Things to do in Natchez

Historic Sites Parks Nature
Highlights from your plan
Longwood ©
Longwood
Rosalie Mansion ©
Rosalie Mansion
Stanton Hall ©
Stanton Hall

1
night
Vicksburg

Vicksburg ©
Vicksburg is the only city and county seat of Warren County, Mississippi, United States. Kick off your visit on the 8th (Mon): admire all the interesting features of Vicksburg National Military Park, make a trip to Vicksburg Riverfront Murals, then take an in-depth tour of U.S.S. Cairo Museum, and finally get a sense of history and politics at Old Courthouse.

To find photos, other places to visit, ratings, and more tourist information, you can read our Vicksburg trip planner .

You can drive from Natchez to Vicksburg in 2 hours. In October, daytime highs in Vicksburg are 31°C, while nighttime lows are 15°C. Wrap up your sightseeing on the 8th (Mon) early enough to drive to Tupelo.

Things to do in Vicksburg

Historic Sites Parks Museums
Highlights from your plan
Vicksburg National Military Park ©
Vicksburg National Military Park
U.S.S. Cairo Museum ©
U.S.S. Cairo Museum
Vicksburg Riverfront Murals ©
Vicksburg Riverfront Murals

1
night
Tupelo

Tupelo ©
Tupelo is the county seat and the largest city of Lee County, Mississippi. On the 9th (Tue), see the interesting displays at Tupelo Automobile Museum, steep yourself in history at Natchez Trace Pkwy, and then browse the exhibits of Elvis Presley Birthplace & Museum.

Inspirock's itinerary builder makes planning a Tupelo trip simple and quick.

Drive from Vicksburg to Tupelo in 5 hours. Alternatively, you can do a combination of bus, taxi, flight, and car; or take a bus. In October, plan for daily highs up to 30°C, and evening lows to 13°C. Wrap up your sightseeing on the 9th (Tue) to allow time to drive to Tunica.

Things to do in Tupelo

Historic Sites Museums Scenic Drive
Highlights from your plan
Elvis Presley Birthplace & Museum ©
Natchez Trace Pkwy ©
Natchez Trace Pkwy
Tupelo Automobile Museum ©
Tupelo Automobile Museum

2
nights
Tunica

Tunica ©
Tunica is a town in and the county seat of Tunica County, Mississippi, near the Mississippi River. Start off your visit on the 10th (Wed): examine the collection at Tunica Museum, then try to win big at Gold Strike Casino, and then try your luck at Horseshoe Casino. Keep things going the next day: tee off at River Bend Links and then try to win big at Tunica Roadhouse Casino.

To find other places to visit, maps, more things to do, and more tourist information, refer to the Tunica online route builder .

Traveling by car from Tupelo to Tunica takes 2.5 hours. Alternatively, you can do a combination of bus and taxi. Expect a daytime high around 28°C in October, and nighttime lows around 13°C. Finish your sightseeing early on the 11th (Thu) to allow enough time to travel back home.

Things to do in Tunica

Casinos Fun & Games Golf
Highlights from your plan
Horseshoe Tunica ©
Horseshoe Tunica
Tunica Museum ©
Tunica Museum
River Bend Links ©
River Bend Links

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