14 days in South Carolina Itinerary

14 days in South Carolina Itinerary

Created using Inspirock South Carolina travel planner

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Route & dates

14 days in South Carolina Itinerary

Start: Asheville
Drive:  1​h 30​min
1
Greenville
— 1 night
Drive:  5​h
2
Myrtle Beach
— 3 nights
Drive:  2​h 30​min
3
Charleston
— 5 nights
Drive:  2​h 30​min
4
Hilton Head
— 3 nights
Drive:  3​h
5
Columbia
— 1 night
Drive:  2​h 45​min
End: Asheville

1
night
Greenville

Greenville ©
The largest city in "upstate" South Carolina, Greenville has grown around the natural wonders of waterfalls located in the downtown area.
Your day-by-day itinerary now includes Greenville Zoo as well as Upcountry History Museum. Kick off your visit on the 4th (Sun): get engrossed in the history at Upcountry History Museum and then take in the dramatic scenery at Falls Park on the Reedy. Keep things going the next day: get to know the resident critters at Greenville Zoo and then make a trip to Artisphere.

To find ratings, photos, and tourist information, use the Greenville trip itinerary website .

Asheville to Greenville is an approximately 1.5-hour car ride. You can also take a bus. Traveling from Asheville in April, Greenville is a bit warmer at night with lows of 53°F. Finish your sightseeing early on the 5th (Mon) to allow enough time to travel to Myrtle Beach.

Things to do in Greenville

Zoos & Aquariums Nature Museums
Highlights from your plan
Falls Park on the Reedy ©
Falls Park on the Reedy
Artisphere ©
Artisphere
Upcountry History Museum ©
Upcountry History Museum

3
nights
Myrtle Beach

Myrtle Beach ©
Myrtle Beach is a coastal city on the east coast of the United States in Horry County, South Carolina. Your day-by-day itinerary now includes Myrtle Beach as well as Pirates Voyage. Go for a jaunt from Myrtle Beach to Murrells Inlet to see Brookgreen Gardens about 30 minutes away. The adventure continues: admire nature's wide array of creatures at Ripley's Aquarium of Myrtle Beach, make a trip to Barefoot Landing, take in the waterfront at Myrtle Beach Boardwalk & Promenade, and wander the streets of Broadway at the Beach.

To find where to stay, more things to do, traveler tips, and more tourist information, use the Myrtle Beach route builder tool .

Getting from Greenville to Myrtle Beach by combination of taxi and flight takes about 3.5 hours. Other options: do a combination of bus and flight; or drive. In April in Myrtle Beach, expect temperatures between 72°F during the day and 56°F at night. Wrap up your sightseeing on the 8th (Thu) early enough to drive to Charleston.

Things to do in Myrtle Beach

Parks Museums Beaches

Side Trips

Barefoot Landing, Brookgreen Gardens
Highlights from your plan
Broadway at the Beach ©
Broadway at the Beach
Ripley's Aquarium of Myrtle Beach ©
Brookgreen Gardens ©
Brookgreen Gardens

5
nights
Charleston

Charleston ©
Many visitors describe their Charleston holiday as a warm embrace by an old, dear friend--who lived about 200 years ago.
You've now added Aiken-Rhett House to your itinerary. There's lots more to do: take in nature's colorful creations at Magnolia Plantation & Gardens, contemplate the long history of Middleton Place, hunt for treasures at Charleston City Market, and make a trip to Charleston Fire Department, Station 2/3.

For photos, where to stay, maps, and other tourist information, refer to the Charleston online journey planner .

Traveling by car from Myrtle Beach to Charleston takes 2.5 hours. Alternatively, you can take a bus. In April, plan for daily highs up to 74°F, and evening lows to 57°F. Wrap up your sightseeing on the 13th (Tue) to allow time to drive to Hilton Head.

Things to do in Charleston

Historic Sites Parks Wildlife

Side Trip

H. L. Hunley
Highlights from your plan
Magnolia Plantation & Gardens ©
Magnolia Plantation & Gardens
Middleton Place ©
Middleton Place
Fort Sumter National Monument ©
Fort Sumter National Monument

3
nights
Hilton Head

Hilton Head ©
A Hilton Head vacation may be heaven for a golfer, but the area also offers all kinds of other options for sports fans.
Your day-by-day itinerary now includes Hilton Head Outfitters as well as Coastal Discovery Museum. Kick off your visit on the 14th (Wed): see majestic marine mammals with a dolphin and whale watching tour, examine the collection at Coastal Discovery Museum, and then gear up at Hilton Head Outfitters. On the next day, walk around Henry C. Chambers Waterfront Park and then enjoy the sand and surf at Coligny Beach.

For reviews, where to stay, photos, and other tourist information, use the Hilton Head online trip maker .

You can drive from Charleston to Hilton Head in 2.5 hours. Alternatively, you can take a bus. Expect a daytime high around 74°F in April, and nighttime lows around 59°F. Wrap up your sightseeing by early afternoon on the 16th (Fri) to allow time for the car ride to Columbia.

Things to do in Hilton Head

Outdoors Parks Wildlife

Side Trip

Beaufort
Highlights from your plan
Pat Conroy Literary Center ©
Pat Conroy Literary Center
Dolphin & Whale Watching
Coligny Beach ©
Coligny Beach

1
night
Columbia

Columbia ©
A compact capital with stately southern history, Columbia serves as a symbol of the south.
South Carolina State Museum has been added to your itinerary. On the 16th (Fri), ponder the world of politics at South Carolina State House.

To find more things to do, other places to visit, and more tourist information, read our Columbia road trip app .

Drive from Hilton Head to Columbia in 3 hours. Alternatively, you can do a combination of taxi and train; or take a bus. Plan for a bit cooler nights when traveling from Hilton Head in April since evenings lows in Columbia dip to 54°F. Wrap up your sightseeing on the 17th (Sat) to allow time to drive back home.

Things to do in Columbia

Parks Zoos & Aquariums Museums
Highlights from your plan
Riverbanks Zoo and Botanical Garden ©
South Carolina State House ©
South Carolina State House
South Carolina State Museum
South Carolina State Museum

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