14 days in South Carolina Itinerary

14 days in South Carolina Itinerary

Created using Inspirock South Carolina trip planner

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Route & dates

14 days in South Carolina Itinerary

Start: Kansas City
Fly + taxi:  6​h
1
Greenville
— 1 night
bus:  1​h 30​min
2
Columbia
— 2 nights
Drive:  3​h
3
Hilton Head
— 2 nights
Drive:  2​h 30​min
4
Folly Beach
— 2 nights
Drive:  30​min
5
Charleston
— 3 nights
Drive:  30​min
6
Isle of Palms
— 2 nights
Drive:  2​h 45​min
7
Myrtle Beach
— 1 night
Fly:  6​h
End: Kansas City

1
night
Greenville

Greenville ©
The largest city in "upstate" South Carolina, Greenville has grown around the natural wonders of waterfalls located in the downtown area.
Kick off your visit on the 16th (Thu): stop by M.Judson Booksellers & Storytellers and then sample the fine beverages at Dark Corner Distillery.

To find maps, reviews, ratings, and tourist information, read our Greenville road trip planner .

Kansas City to Greenville is an approximately 6-hour combination of flight and taxi. You can also drive; or take a bus. The time zone difference moving from Central Standard Time (CST) to Eastern Standard Time (EST) is 1 hour. Plan for a bit warmer temperatures traveling from Kansas City in April, with highs in Greenville at 74°F and lows at 53°F. Finish your sightseeing early on the 17th (Fri) so you can take a bus to Columbia.

Things to do in Greenville

Parks Outdoors Trails
Highlights from your plan
Falls Park on the Reedy ©
Falls Park on the Reedy
Room Escape Games
Dark Corner Distillery ©
Dark Corner Distillery

2
nights
Columbia

Columbia ©
A compact capital with stately southern history, Columbia serves as a symbol of the south.
Kick off your visit on the 18th (Sat): examine the collection at Fort Jackson Museum (not open to All public), explore the striking landscape of Congaree National Park, and then see the interesting displays at South Carolina State Museum. Here are some ideas for day two: admire the striking features of South Carolina State House, test your problem-solving skills at popular escape rooms, and then get to know the resident critters at Riverbanks Zoo and Botanical Garden.

To find more things to do, traveler tips, other places to visit, and other tourist information, read Columbia trip planner .

Traveling by bus from Greenville to Columbia takes 1.5 hours. Alternatively, you can drive. Expect a daytime high around 77°F in April, and nighttime lows around 54°F. Cap off your sightseeing on the 19th (Sun) early enough to go by car to Hilton Head.

Things to do in Columbia

Parks Nature Zoos & Aquariums

Side Trip

Congaree National Park
Highlights from your plan
Congaree National Park ©
Congaree National Park
Riverbanks Zoo and Botanical Garden ©
South Carolina State House ©
South Carolina State House

2
nights
Hilton Head

A Hilton Head vacation may be heaven for a golfer, but the area also offers all kinds of other options for sports fans.
On the 20th (Mon), see the interesting displays at Coastal Discovery Museum, get a new perspective on things with Boat Tours & Water Sports, and then take a memorable tour with Tours. On your second day here, see what you can catch with a fishing tour, then stroll through Hilton Head Island Bike Trails, and then putt your heart out at Legendary Golf.

For ratings, photos, where to stay, and tourist information, read our Hilton Head day trip site .

Getting from Columbia to Hilton Head by car takes about 3 hours. Other options: do a combination of train and taxi; or take a bus. Expect a daytime high around 74°F in April, and nighttime lows around 59°F. Cap off your sightseeing on the 21st (Tue) early enough to go by car to Folly Beach.

Things to do in Hilton Head

Outdoors Tours Wildlife
Highlights from your plan
Waterskiing & Jetskiing
Hilton Head Island Bike Trails ©
Hilton Head Island Bike Trails
Speed Boats Tours

2
nights
Folly Beach

Folly Beach is a city located on Folly Island in Charleston County, South Carolina, United States. On the 22nd (Wed), take in the waterfront at Folly Beach Fishing Pier and then enjoy the sand and surf at Folly Beach Public Beach. Get ready for a full day of sightseeing on the next day: stroll through Lighthouse Inlet Heritage Preserve, find your balance on the water with some of the best stand-up paddleboarding in the area, and then get up close to creatures of the deep with a dolphin and whale watching tour.

To see ratings, traveler tips, photos, and more tourist information, refer to the Folly Beach trip planner .

Getting from Hilton Head to Folly Beach by car takes about 2.5 hours. Other options: do a combination of bus and car. In April, daytime highs in Folly Beach are 74°F, while nighttime lows are 57°F. Wrap up your sightseeing on the 23rd (Thu) to allow time to drive to Charleston.

Things to do in Folly Beach

Outdoors Beaches Parks
Highlights from your plan
Dolphin & Whale Watching
Folly Beach Public Beach ©
Folly Beach Public Beach
Stand-Up Paddleboarding

3
nights
Charleston

Many visitors describe their Charleston holiday as a warm embrace by an old, dear friend--who lived about 200 years ago.
Charleston is known for parks, historic sites, shopping, wildlife, and nightlife. Your plan includes some of its best attractions: take in the local highlights with Walking tours, go for a charming ride with a horse-drawn carriage tour, admire the natural beauty at Magnolia Plantation & Gardens, and test your team's savvy at popular escape rooms.

To see photos, reviews, traveler tips, and tourist information, use the Charleston trip itinerary builder .

Charleston is just a short distance from Folly Beach. Expect a daytime high around 74°F in April, and nighttime lows around 57°F. Wrap up your sightseeing on the 26th (Sun) to allow time to drive to Isle of Palms.

Things to do in Charleston

Tours Historic Sites Outdoors
Highlights from your plan
Horse-Drawn Carriage Tours
Stand-Up Paddleboarding
Fishing Charters & Tours

2
nights
Isle of Palms

Isle of Palms ©
Isle of Palms is a city in Charleston County, South Carolina, United States. On the 27th (Mon), steep yourself in history at Boone Hall Plantation, then identify plant and animal life at The Center for Birds of Prey, and then appreciate the history behind Fort Moultrie. Get ready for a full day of sightseeing on the next day: admire the majestic nature at Isle of Palms County Park.

To see where to stay, ratings, more things to do, and more tourist information, use the Isle of Palms online route planner .

Isle of Palms is very close to Charleston. In April, daytime highs in Isle of Palms are 74°F, while nighttime lows are 57°F. Finish your sightseeing early on the 28th (Tue) so you can travel to Myrtle Beach.

Things to do in Isle of Palms

Parks Nature Historic Sites

Side Trips

Fort Moultrie, The Center for Birds of Prey, Boone Hall Plantation
Highlights from your plan
Isle of Palms County Park ©
Isle of Palms County Park
Boone Hall Plantation ©
Boone Hall Plantation
Fort Moultrie ©
Fort Moultrie

1
night
Myrtle Beach

Myrtle Beach ©
Myrtle Beach is a coastal city on the east coast of the United States in Horry County, South Carolina. On the 29th (Wed), grab your bike and head to Pee Dee Bicycle, then wander the streets of Broadway at the Beach, then get up close and personal with brilliant marine life at Ripley's Aquarium of Myrtle Beach, and finally catch some excitement at Myrtle Beach SkyWheel.

To see traveler tips, where to stay, other places to visit, and more tourist information, read Myrtle Beach driving holiday app .

Getting from Isle of Palms to Myrtle Beach by car takes about 2 hours. April in Myrtle Beach sees daily highs of 72°F and lows of 56°F at night. Finish up your sightseeing early on the 29th (Wed) so you can travel back home.

Things to do in Myrtle Beach

Parks Zoos & Aquariums Shopping
Highlights from your plan
Broadway at the Beach ©
Broadway at the Beach
Myrtle Beach SkyWheel ©
Myrtle Beach SkyWheel
Ripley's Aquarium of Myrtle Beach ©
Ripley's Aquarium of Myrtle Beach

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