14 days in Tennessee, North Carolina & South Carolina Itinerary

14 days in Tennessee, North Carolina & South Carolina Itinerary

Created using Inspirock United States travel planner

Make it your trip
Fly
1
Great Smoky Mountains National Park
— 3 nights
Drive
2
Asheville
— 4 nights
Drive
3
Greenville
— 1 night
Drive
4
Burlington
— 1 night
Drive
5
Charleston
— 3 nights
Drive
6
Bluffton
— 1 night
Fly

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Great Smoky Mountains National Park

— 3 nights

A Wondrous Diversity of Life

Great Smoky Mountains National Park contains some of the highest mountains east of the Mississippi River, but it's the ease of access that makes this national park the United States' most visited.
Visiting Clingmans Dome and Newfound Gap Road will get you outdoors. There's much more to do: cruise along Little River Road, tour the pleasant surroundings at Roaring Fork, trek along Rainbow Falls Trail, and don't miss a visit to Elkmont Ghost Town.

For where to stay, other places to visit, more things to do, and tourist information, you can read our Great Smoky Mountains National Park road trip app.

New York City to Great Smoky Mountains National Park is an approximately 3.5-hour flight. You can also drive; or take a bus. Traveling from New York City in November, Great Smoky Mountains National Park is a bit cooler at night with lows of 39°F. Finish your sightseeing early on the 30th (Tue) so you can travel to Asheville.

Things to do in Great Smoky Mountains National Park

Outdoors · Parks · Trails · Scenic Drive

Asheville

— 4 nights

Land of the Sky

Asheville nestles between two major mountain ranges in the scenic western section of North Carolina.
Take a break from the city and head to Blue Ridge Pkwy and Max Patch. Venture out of the city with trips to Gatlinburg (Zipline, Sugarlands Distilling Company, &more). There's more to do: get a dose of the wild on Tumblestone Tours and Transportation and take in the exciting artwork at New Morning Gallery.

For maps, reviews, and other tourist information, use the Asheville holiday maker.

The Route module can help you plan travel from Great Smoky Mountains National Park to Asheville. November in Asheville sees daily highs of 59°F and lows of 36°F at night. Finish your sightseeing early on the 4th (Sat) to allow enough time to drive to Greenville.

Things to do in Asheville

Outdoors · Parks · Nature · Tours

Side Trips

Greenville

— 1 night

Textile Center of the World

The largest city in "upstate" South Carolina, Greenville has grown around the natural wonders of waterfalls located in the downtown area.
On the 5th (Sun), tour the pleasant surroundings at Lake Conestee Nature Park, snap pictures at Liberty Bridge, and then take in the dramatic scenery at Falls Park on the Reedy.

To find more things to do, where to stay, reviews, and tourist information, refer to the Greenville travel itinerary planner.

Drive from Asheville to Greenville in 1.5 hours. Alternatively, you can take a bus. Traveling from Asheville in December, Greenville is a bit warmer at night with lows of 41°F. Finish your sightseeing early on the 5th (Sun) to allow enough time to travel to Burlington.

Things to do in Greenville

Parks · Wildlife · Nature

Side Trip

Burlington

— 1 night
Burlington is a city in Alamance County in the U.S. state of North Carolina. Start off your visit on the 6th (Mon): hike along Haw River Trail & Paddle Trail and then tour the pleasant surroundings at Conservators Center.

For reviews, traveler tips, other places to visit, and other tourist information, you can read our Burlington journey maker site.

You can drive from Greenville to Burlington in 3.5 hours. Another option is to do a combination of car and flight. Traveling from Greenville in December, Burlington is slightly colder at night with lows of 36°F. Finish up your sightseeing early on the 6th (Mon) so you can travel to Charleston.

Things to do in Burlington

Parks · Wildlife · Trails · Outdoors

Charleston

— 3 nights
Many visitors describe their Charleston holiday as a warm embrace by an old, dear friend--who lived about 200 years ago.
Get outdoors at Horse-Drawn Carriage Tours and Stand-Up Paddleboarding. Go for a jaunt from Charleston to Awendaw to see The Center for Birds of Prey about 38 minutes away. There's much more to do: get a dose of the wild on Charleston Fossil Adventures, go on a hair-raising tour with a ghost and vampire tour, capture your vacation like a pro with an inspiring photography tour, and get engrossed in the history at Fort Sumter National Monument.

To see other places to visit, traveler tips, maps, and other tourist information, you can read our Charleston online sightseeing planner.

Drive from Burlington to Charleston in 5 hours. Alternatively, you can do a combination of car and flight. Expect somewhat warmer temperatures when traveling from Burlington in December; daily highs in Charleston reach 63°F and lows reach 46°F. Wrap up your sightseeing on the 9th (Thu) to allow time to drive to Bluffton.

Things to do in Charleston

Tours · Wildlife · Outdoors · Museums

Side Trip

Bluffton

— 1 night
Bluffton is a Lowcountry town in Beaufort County, South Carolina, United States. On the 10th (Fri), steep yourself in history at Heyward House Museum & Welcome Center, see majestic marine mammals with May River Excursions, and then take in the architecture and atmosphere at The Church of the Cross.

Before you visit Bluffton, use our trip planner to discover what you can do and see there.

Traveling by car from Charleston to Bluffton takes 2 hours. Alternatively, you can do a combination of bus and taxi. In December in Bluffton, expect temperatures between 64°F during the day and 48°F at night. Wrap up your sightseeing on the 10th (Fri) to allow time to fly back home.

Things to do in Bluffton

Historic Sites · Wildlife · Tours · Outdoors

Tennessee travel guide

4.4
Specialty Museums · Distilleries · Theme Parks
The Volunteer State
Divided by law, geography, and custom into three major regions, represented by the three stars on state's flag, Tennessee boasts a distinctive musical heritage that includes elements of bluegrass, country-western, and blues. With a countryside as diverse as its people, Tennessee includes landscapes ranging from a mountainous region in the east to the lowlands of the west, with gently rolling hills in the middle. For a well-rounded vacation, you can hike remote mountain trails in the morning and explore the crowded bars of Nashville in the evening. Visit the urban attractions, such as Elvis Presley's former residence in Memphis, but don't miss a chance to spend some time in the Great Smoky Mountains National Park, situated in the eastern part of the state.

North Carolina travel guide

4.4
History Museums · Specialty Museums · Zipline
The Tar Heel State
A top destination for a holiday in nature, North Carolina provides a seemingly endless variety of outdoor activities, including hiking, mountain climbing, and skiing. While the state's rural regions offer a taste of traditional Appalachian music and culture, its increasingly diverse big cities feature modern skyscrapers, renowned museums, and historical neighborhoods perfect for sightseeing tours. The coastal region, famous for its year-round temperate climate, attracts millions of annual visitors, making North Carolina the sixth most-visited state in the country. Though it's hard to find a quiet time of year in coastal North Carolina, the state's inland areas retain many secluded corners where you can experience the laid-back Old South atmosphere.

South Carolina travel guide

4.3
Dolphin & Whale Watching · Gardens · Beaches
The Palmetto State
Composed of five distinct geographic regions with boundaries roughly parallel to the Atlantic coastline, South Carolina embraces rich history, scenic beauty, and outstanding cuisine. Originally established as a slave society dependent on the cultivation of rice and indigo, the state now boasts a diverse economy that includes massive production of textile goods, chemical products, machinery, and automobiles. Widely regarded as the beginning of the Deep South, the state remains a deeply conservative part of the country, fervently clinging to its religious and cultural traditions. South Carolinians are kind and open hosts to those who vacation here, eager to share the wealth of their cultural heritage with curious visitors. With many remarkable places to visit like Charleston and Hilton Head, your itinerary here is sure to be diverse and full of scenic attractions.