15 days in Florida Keys Itinerary

The northernmost island of the Florida Keys, Key Largo provides stunning scenery, a number of watersports opportunities, and plenty of areas to relax on vacation.

Key Largo is known for wildlife, nature, and adventure. Your trip includes some of its best attractions: discover the deep blue sea with a scuba or snorkeling tour, indulge in some personalized pampering at some of the best spas, get up close and personal with brilliant marine life at Island Dolphin Care, and explore the gorgeous colors at Spiegel Grove.

To see other places to visit, photos, reviews, and tourist information, use the Key Largo online journey builder.

Manchester, UK to Key Largo is an approximately 14.5-hour flight. The time zone difference moving from Greenwich Mean Time (GMT) to Eastern Standard Time (EST) is minus 5 hours. Plan for warmer temperatures traveling from Manchester in May, with highs in Key Largo at 34°C and lows at 26°C. Finish your sightseeing early on the 15th (Wed) so you can drive to Key West.

Located just 140 km (90 mi) from Cuba, Key West is an island only about 6.4 km (4 mi) long and 1.6 km (1 mi) wide.

Key West is known for sightseeing, wildlife, and adventure. Your trip includes some of its best attractions: examine the collection at The Ernest Hemingway Home and Museum, make a trip to Duval Street, take a memorable drive along The Overseas Highway, and steep yourself in history at Truman Little White House.

To see photos, other places to visit, maps, and tourist information, go to the Key West online trip itinerary planner.

Getting from Key Largo to Key West by car takes about 2.5 hours. Other options: take a bus. In May in Key West, expect temperatures between 34°C during the day and 29°C at night. Finish up your sightseeing early on the 20th (Mon) so you can go by car to Marathon.

A tiny city just 16 km (10 mi) long, Marathon is spread across several islands in the middle of the Florida Keys.

Explore Marathon's surroundings by going to Fishing Charters & Tours (in Big Pine Key) and SpaTerre at Little Palm Island Resort (in Little Torch Key). Next up on the itinerary: kick back and relax at Bahia Honda State Park, look for all kinds of wild species at The Turtle Hospital, see the interesting displays at Crane Point Museum & Nature Center, and get a taste of the local shopping with Paradise Produce.

To see ratings, photos, maps, and other tourist information, use the Marathon trip itinerary website.

Drive from Key West to Marathon in 1.5 hours. Alternatively, you can take a bus. In May, plan for daily highs up to 36°C, and evening lows to 29°C. Finish up your sightseeing early on the 23rd (Thu) so you can go by car to Islamorada.

Islamorada, long recognized as one of the world's top spots for sport fishing, encompasses six islands in the Florida Keys.

Start off your visit on the 24th (Fri): get engrossed in the history at History of Diving Museum, then take a tour by water with Boat Tours & Water Sports, then sample the tasty concoctions at Islamorada Brewery & Distillery - MM82, and finally relax and rejuvenate at some of the top local wellness centers. Get ready for a full day of sightseeing on the 25th (Sat): stroll through Anne's Beach, sample the tasty concoctions at Florida Keys Brewing Company, and then view the masterpieces at Pasta Pantaleo Signature Gallery.

To find traveler tips, photos, reviews, and more tourist information, use the Islamorada road trip app.

Getting from Marathon to Islamorada by car takes about an hour. Other options: take a bus. In May in Islamorada, expect temperatures between 36°C during the day and 29°C at night. Cap off your sightseeing on the 26th (Sun) early enough to catch the flight back home.