16 days in Las Vegas, New Orleans & Florida Keys Itinerary

Nicknamed the "Entertainment Capital of the World," Las Vegas sits in the middle of a desert in the southern section of Nevada.

On the 19th (Fri), have fun at Battlefield Vegas. Get ready for a full day of sightseeing on the 20th (Sat): try your luck at Casino at Luxor Las Vegas, then take an in-depth tour of Titanic, and then immerse yourself in nature at Valley of Fire State Park.

To find other places to visit, ratings, maps, and tourist information, you can read our Las Vegas itinerary planner .

London, UK to Las Vegas is an approximately 14.5-hour flight. You can also do a combination of train and flight. Traveling from London to Las Vegas, you'll gain 8 hours due to the time zone difference. When traveling from London in April, plan for much warmer days and a bit warmer nights in Las Vegas: temperatures range from 31°C by day to 16°C at night. Finish your sightseeing early on the 21st (Sun) to allow enough time to travel to New Orleans.

Known for its Creole cuisine, rich musical tradition, and nearby swamps and plantations, New Orleans is one of the nation's oldest cities.

Kick off your visit on the 22nd (Mon): examine the collection at Blaine Kern's Mardi Gras World, steep yourself in history at Laura Plantation: Louisiana's Creole Heritage Site, then contemplate the long history of Oak Alley Plantation, and finally examine the collection at Museum of Trade Finance and the Fed. Keep things going the next day: see the interesting displays at The Presbytere, then tour the pleasant surroundings at Audubon Zoo, and then stroll through New Orleans City Park.

For reviews, maps, more things to do, and more tourist information, go to the New Orleans holiday planner.

You can fly from Las Vegas to New Orleans in 6 hours. Alternatively, you can do a combination of flight and bus; or drive. You'll lose 2 hours traveling from Las Vegas to New Orleans due to the time zone difference. While traveling from Las Vegas, expect a bit cooler days and a bit warmer nights in New Orleans, ranging from highs of 25°C to lows of 25°C. Finish up your sightseeing early on the 23rd (Tue) so you can travel to Key West.

Located just 140 km (90 mi) from Cuba, Key West is an island only about 6.4 km (4 mi) long and 1.6 km (1 mi) wide.

Eschew the tourist crowds and head to Dolphin & Whale Watching and Scuba & Snorkeling. There's lots more to do: take a tour by water with Boat Tours & Water Sports, brush up on your military savvy at U.S. Coast Guard Cutter Ingham Maritime Museum, glide peacefully along the water with some of the best stand-up paddleboarding in the area, and stroll the grounds of Key West Cemetery.

To find photos, where to stay, more things to do, and tourist information, go to the Key West online route planner .

You can fly from New Orleans to Key West in 6.5 hours. Other options are to do a combination of flight and shuttle; or drive. Traveling from New Orleans to Key West, you'll lose 1 hour due to the time zone difference. Traveling from New Orleans in April, you will find days in Key West are somewhat warmer (33°C), and nights are about the same (27°C). Finish up your sightseeing early on the 26th (Fri) so you can catcht the bus to Big Pine Key.

Big Pine Key is a census-designated place and unincorporated community in Monroe County, Florida, United States, on an island of the same name in the Florida Keys. Start off your visit on the 27th (Sat): cast your line with a fishing tour and then admire the majestic nature at Bahia Honda State Park.

For more things to do, ratings, maps, and tourist information, read our Big Pine Key trip planner.

Getting from Key West to Big Pine Key by bus takes about an hour. Other options: drive. In April in Big Pine Key, expect temperatures between 35°C during the day and 28°C at night. Wrap up your sightseeing on the 27th (Sat) early enough to take a bus to Marathon.

A tiny city just 16 km (10 mi) long, Marathon is spread across several islands in the middle of the Florida Keys.

Eschew the tourist crowds and head to The Turtle Hospital and Seven Mile Bridge. There's lots more to do: identify plant and animal life at Dolphin Research Center, soothe aching muscles at some of the top local wellness centers, tour the pleasant surroundings at Sombrero Beach, and meet the residents at Florida Keys Aquarium Encounters.

To see reviews, traveler tips, maps, and other tourist information, read Marathon trip itinerary builder site .

Marathon is just a short distance from Big Pine Key. In April, daytime highs in Marathon are 35°C, while nighttime lows are 28°C. Wrap up your sightseeing on the 30th (Tue) to allow time to drive to Islamorada.

Islamorada, long recognized as one of the world's top spots for sport fishing, encompasses six islands in the Florida Keys.

Start off your visit on the 1st (Wed): see some colorful creatures with a scuba or snorkeling tour and then see what you can catch with a fishing tour. Get ready for a full day of sightseeing on the next day: glide through the air with a parasailing or paragliding tour, shop like a local with Old Road Gallery, glide peacefully along the water with some of the best stand-up paddleboarding in the area, then take an in-depth tour of History of Diving Museum, then look for gifts at Bella Sol Fragrance Bar and Gifts, and finally indulge your thirst for a good beer at Islamorada Beer Company Brewery and Tasting Room.

For reviews, where to stay, traveler tips, and more tourist information, refer to the Islamorada trip planner .

Getting from Marathon to Islamorada by car takes about an hour. Other options: take a bus. In April, daytime highs in Islamorada are 35°C, while nighttime lows are 28°C. Finish up your sightseeing early on the 2nd (Thu) so you can go by car to Key Largo.

The northernmost island of the Florida Keys, Key Largo provides stunning scenery, a number of watersports opportunities, and plenty of areas to relax on vacation.

On the 3rd (Fri), look for all kinds of wild species at Florida Keys Wild Bird Rehabilitation Center, then admire nature's wide array of creatures at Island Dolphin Care, then fly like a bird with a parasailing or paragliding tour, and finally take in the architecture and atmosphere at Key Largo Baptist Church.

For more things to do, maps, reviews, and tourist information, read Key Largo tour planner.

You can drive from Islamorada to Key Largo in an hour. Another option is to do a combination of bus and taxi. Expect slightly colder evenings in Key Largo when traveling from Islamorada in May, with lows around 26°C. Wrap up your sightseeing on the 3rd (Fri) early enough to travel back home.