16 days in San Francisco, Los Angeles & Las Vegas Itinerary

San Francisco is a top holiday destination featuring scenic beauty and great ethnic and cultural diversity.

Eschew the tourist crowds and head to San Francisco Bay and Lands End. Dedicate the 2nd (Sat) to wine at some of the top wineries in the area. There's lots more to do: stroll around Golden Gate Park, savor the flavors at Food & Drink, get thoroughly spooked out with a ghost and vampire tour, and take in nature's colorful creations at San Francisco Botanical Garden.

For photos, where to stay, reviews, and more tourist information, refer to the San Francisco trip maker.

Amsterdam, The Netherlands to San Francisco is an approximately 13.5-hour flight. Traveling from Amsterdam to San Francisco, you'll gain 9 hours due to the time zone difference. Plan for a bit warmer temperatures traveling from Amsterdam in September, with highs in San Francisco at 28°C and lows at 17°C. Wrap up your sightseeing on the 6th (Wed) to allow time to fly to Los Angeles.

Surrounded by mountain ranges, forests, valleys, beaches, and deserts, the metropolitan area of Los Angeles is home to over 17 million people.

Discover out-of-the-way places like Calboat Diving - Spectre Dive Boat and 26-Mile Bike Path. Explore Los Angeles' surroundings by going to Ventura (San Buenaventura State Beach & Topa Topa Brewing Company), Huntington Beach Pier (in Huntington Beach) and Newport Beach (in Newport Beach). There's still lots to do: learn about all things military at Battleship USS Iowa Museum, test your problem-solving skills at popular escape rooms, don't miss a visit to The Wizarding World of Harry Potter, and admire the masterpieces at The Broad.

Discover how to plan a Los Angeles trip in just a few steps with Inspirock's itinerary builder.

Getting from San Francisco to Los Angeles by flight takes about 3 hours. Other options: drive; or take a bus. Traveling from San Francisco in September, things will get a bit warmer in Los Angeles: highs are around 34°C and lows about 22°C. Finish up your sightseeing early on the 11th (Mon) so you can catch the flight to Las Vegas.

Nicknamed the "Entertainment Capital of the World," Las Vegas sits in the middle of a desert in the southern section of Nevada.

Step off the beaten path and head to Food Tours and Room Escape Games. Step out of Las Vegas with an excursion to Lion Habitat Ranch in Henderson--about 32 minutes away. There's still lots to do: get active on the water at Water Sports, trot along with a tour on horseback, see the interesting displays at Shelby American Inc, and don't miss a visit to Welcome to Fabulous Las Vegas Sign.

For where to stay and other tourist information, you can read our Las Vegas trip itinerary planner.

You can fly from Los Angeles to Las Vegas in 3 hours. Alternatively, you can drive; or take a bus. Expect a bit warmer weather when traveling from Los Angeles in September: highs in Las Vegas hover around 39°C, while lows dip to 25°C. Cap off your sightseeing on the 16th (Sat) early enough to catch the flight back home.