16 days in San Francisco, New Orleans & Florida Itinerary

16 days in San Francisco, New Orleans & Florida Itinerary

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Route & dates

16 days in San Francisco, New Orleans & Florida Itinerary

Start: Manchester
Fly:  13​h 45​min
1
San Francisco
— 2 nights
Fly:  6​h 15​min
2
New Orleans
— 1 night
Drive:  4​h 30​min
3
Destin
— 1 night
Drive:  1​h 15​min
4
Panama City Beach
— 2 nights
Drive:  5​h 30​min
5
St. Augustine
— 1 night
Drive:  6​h
6
Marco Island
— 1 day
ferry:  2​h 30​min
7
Key West
— 3 nights
bus:  1​h 15​min
8
Marathon
— 1 night
bus + Fly:  14​h 30​min
End: Manchester

2
nights
San Francisco

San Francisco ©
San Francisco is a top holiday destination featuring scenic beauty and great ethnic and cultural diversity.
Kick off your visit on the 31st (Sat): don't miss a visit to Lombard Street and then snap pictures at Golden Gate Bridge. Get ready for a full day of sightseeing on the next day: take a memorable ride with Cable Cars, take in the waterfront at Fisherman's Wharf, and then head off the coast to Alcatraz Island.

To find traveler tips, where to stay, other places to visit, and other tourist information, go to the San Francisco attractions planner .

Manchester, UK to San Francisco is an approximately 14-hour flight. You can also do a combination of flight and subway; or do a combination of train, flight, and subway. Traveling from Manchester to San Francisco, you'll gain 8 hours due to the time zone difference. Plan for somewhat warmer temperatures traveling from Manchester in August, with highs in San Francisco at 26°C and lows at 17°C. Finish your sightseeing early on the 2nd (Mon) to allow enough time to travel to New Orleans.

Things to do in San Francisco

Parks Nature Historic Sites
Highlights from your plan
Golden Gate Bridge ©
Golden Gate Bridge
Alcatraz Island ©
Alcatraz Island
Fisherman's Wharf ©
Fisherman's Wharf

1
night
New Orleans

New Orleans ©
Known for its Creole cuisine, rich musical tradition, and nearby swamps and plantations, New Orleans is one of the nation's oldest cities.
Start off your visit on the 3rd (Tue): take a stroll through Royal Street, then learn about all things military at The National WWII Museum, and then get to know the fascinating history of Garden District. Get ready for a full day of sightseeing on the next day: explore the different monuments and memorials at Lafayette Cemetery No.1, then tour the pleasant surroundings at New Orleans City Park, and then get to know the fascinating history of French Quarter.

To see ratings, where to stay, maps, and tourist information, go to the New Orleans online trip planner .

Traveling by flight from San Francisco to New Orleans takes 6.5 hours. Alternatively, you can do a combination of subway and flight; or drive. Traveling from San Francisco to New Orleans, you'll lose 2 hours due to the time zone difference. While traveling from San Francisco, expect a bit warmer days and much hotter nights in New Orleans, ranging from highs of 33°C to lows of 33°C. Wrap up your sightseeing on the 4th (Wed) to allow time to drive to Destin.

Things to do in New Orleans

Historic Sites Neighborhoods Museums
Highlights from your plan
Royal Street ©
Royal Street
The National WWII Museum ©
The National WWII Museum
New Orleans City Park ©
New Orleans City Park

1
night
Destin

With emerald water and white beaches, Destin is one of America's favorite vacation destinations.
Start off your visit on the 5th (Thu): look for gifts at Sexton's Seafood Market, then fly like a bird with a parasailing or paragliding tour, then make a trip to Destin Harbor Boardwalk, and finally get up close to creatures of the deep with a dolphin and whale watching tour.

To see other places to visit, ratings, reviews, and other tourist information, you can read our Destin route builder app .

You can drive from New Orleans to Destin in 4.5 hours. Alternatively, you can do a combination of flight and taxi; or take a bus. Traveling from New Orleans in September, you can expect nighttime temperatures to be little chillier in Destin, with lows of 28°C. Finish your sightseeing early on the 5th (Thu) to allow enough time to drive to Panama City Beach.

Things to do in Destin

Outdoors Tours Adventure
Highlights from your plan
Dolphin & Whale Watching
Parasailing & Paragliding
Destin Harbor Boardwalk ©
Destin Harbor Boardwalk

2
nights
Panama City Beach

Panama City Beach ©
Boasting 43 km (27 mi) of white sandy beaches and plenty of sunshine, Panama City Beach is an ideal choice for a relaxing holiday.
On the 6th (Fri), get up close to creatures of the deep with a dolphin and whale watching tour, browse the different shops at Pier Park, and then cool off at Panama City Beach. Get ready for a full day of sightseeing on the next day: meet the residents at Gulf World Marine Park, learn about winemaking at Panama City Beach Winery, then tour the pleasant surroundings at St. Andrews State Park, and finally look for gifts at Little Village.

Find out how to plan Panama City Beach trip without stress by asking Inspirock to help create an itinerary.

You can drive from Destin to Panama City Beach in 1.5 hours. Another option is to do a combination of taxi and bus. Traveling from Destin to Panama City Beach, you'll lose 1 hour due to the time zone difference. Traveling from Destin in September, you can expect nighttime temperatures to be slightly colder in Panama City Beach, with lows of 24°C. Wrap up your sightseeing on the 7th (Sat) to allow time to drive to St. Augustine.

Things to do in Panama City Beach

Outdoors Parks Beaches
Highlights from your plan
Panama City Beach Winery ©
Panama City Beach Winery
Panama City Beach ©
Panama City Beach
Dolphin & Whale Watching

1
night
St. Augustine

St. Augustine ©
SAINT AUGUSTINE | PONTE VEDRA on Florida's Historic Coast The Nation's oldest city (est. On the 8th (Sun), brush up on your knowledge of spirits at St. Augustine Distillery, then kick back and relax at St. Augustine Beach, then visit a coastal fixture at St. Augustine Lighthouse & Maritime Museum, and finally look for gifts at Faux Paws. Keep things going the next day: don't miss a visit to St. George Street, identify plant and animal life at St. Augustine Alligator Farm Zoological Park, and then admire all the interesting features of Flagler College.

Inspirock's itinerary builder makes planning a St. Augustine trip simple and quick.

Drive from Panama City Beach to St. Augustine in 5.5 hours. Alternatively, you can do a combination of taxi, flight, and bus; or do a combination of car, flight, and bus. September in St. Augustine sees daily highs of 34°C and lows of 26°C at night. Finish your sightseeing early on the 9th (Mon) to allow enough time to drive to Marco Island.

Things to do in St. Augustine

Parks Wildlife Beaches
Highlights from your plan
St. Augustine Beach ©
St. Augustine Beach
St. Augustine Distillery ©
St. Augustine Distillery

1
day
Marco Island

Marco Island is a city in Collier County, Florida, United States, located on an island by the same name in the Gulf of Mexico off the coast of Southwest Florida. Kick off your visit on the 10th (Tue): view the masterpieces at Malenda Trick Art Gallery, then take a memorable tour with Tours, then don't miss a visit to Marco Island Center for the Arts, and finally zoom along the surf with a waterskiing or jet-skiing adventure.

For where to stay and other tourist information, use the Marco Island day trip planning app .

Drive from St. Augustine to Marco Island in 6 hours. Alternatively, you can do a combination of car, flight, bus, and taxi; or do a combination of bus, flight, and taxi. In September, plan for daily highs up to 37°C, and evening lows to 27°C. Finish your sightseeing early on the 10th (Tue) so you can ride a ferry to Key West.

Things to do in Marco Island

Outdoors Adventure Tours
Highlights from your plan
Waterskiing & Jetskiing
Parasailing & Paragliding
Malenda Trick Art Gallery ©
Malenda Trick Art Gallery

3
nights
Key West

Located just 140 km (90 mi) from Cuba, Key West is an island only about 6.4 km (4 mi) long and 1.6 km (1 mi) wide.
Eschew the tourist crowds and head to Dry Tortugas National Park and Fort Zachary Taylor. Next up on the itinerary: get a new perspective on things with Boat Tours & Water Sports, learn about all things military at U.S. Coast Guard Cutter Ingham Maritime Museum, identify plant and animal life at Wildlife Areas, and relax and rejuvenate at some of the top local wellness centers.

For photos, reviews, maps, and tourist information, use the Key West online trip maker .

Getting from Marco Island to Key West by ferry takes about 2.5 hours. Other options: drive. Expect a bit warmer evenings in Key West when traveling from Marco Island in September, with lows around 31°C. Finish your sightseeing early on the 13th (Fri) to allow enough time to take a bus to Marathon.

Things to do in Key West

Outdoors Tours Nature
Highlights from your plan
Dolphin & Whale Watching
Dry Tortugas National Park ©
Dry Tortugas National Park
Fishing Charters & Tours

1
night
Marathon

Marathon ©
A tiny city just 16 km (10 mi) long, Marathon is spread across several islands in the middle of the Florida Keys.
Start off your visit on the 14th (Sat): stroll through Bahia Honda State Park, then take in the views from Old Seven Mile Bridge, then take in the views from Seven Mile Bridge, and finally look for all kinds of wild species at The Turtle Hospital.

To find traveler tips, maps, photos, and more tourist information, you can read our Marathon trip itinerary maker .

Take a bus from Key West to Marathon in 1.5 hours. Alternatively, you can drive. In September, daytime highs in Marathon are 38°C, while nighttime lows are 30°C. Wrap up your sightseeing on the 14th (Sat) to allow time to travel back home.

Things to do in Marathon

Parks Nature Beaches

Side Trip

Bahia Honda State Park
Highlights from your plan
The Turtle Hospital ©
The Turtle Hospital
Bahia Honda State Park ©
Bahia Honda State Park
Seven Mile Bridge ©
Seven Mile Bridge

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