16 days in South Carolina Itinerary

16 days in South Carolina Itinerary

Created using Inspirock South Carolina vacation planner

Make it your trip
Fly
1
Greenville
— 1 night
Drive
2
Columbia
— 1 night
Drive
3
Hilton Head
— 3 nights
Drive
4
Beaufort
— 2 nights
Drive
5
Charleston
— 5 nights
Drive
6
Myrtle Beach
— 3 nights
Fly

S M T W T F S
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29

Greenville

— 1 night

Textile Center of the World

The largest city in "upstate" South Carolina, Greenville has grown around the natural wonders of waterfalls located in the downtown area.
Kick off your visit on the 8th (Sat): sample the fine beverages at Dark Corner Distillery and then stroll around Falls Park on the Reedy. Get ready for a full day of sightseeing on the 9th (Sun): relax in the rural setting at Southern Hills Lavender, then admire the majestic nature at Caesars Head State Park, then contemplate the long history of Hagood Creek Petroglyph Site, and finally snap pictures at Liberty Bridge.

To find other places to visit, ratings, traveler tips, and tourist information, read Greenville road trip planning app.

San Diego to Greenville is an approximately 8-hour flight. You can also drive; or take a bus. Traveling from San Diego to Greenville, you'll lose 3 hours due to the time zone difference. When traveling from San Diego in May, plan for a bit warmer days and about the same nights in Greenville: temperatures range from 81°F by day to 60°F at night. Finish your sightseeing early on the 9th (Sun) to allow enough time to drive to Columbia.

Things to do in Greenville

Nature · Parks · Museums · Historic Sites

Side Trips

Columbia

— 1 night

Capital of Southern Hospitality

A compact capital with stately southern history, Columbia serves as a symbol of the south.
On the 10th (Mon), take in the architecture and design of Cocky Statue, then get to know the resident critters at Riverbanks Zoo and Botanical Garden, then admire nature's wide array of creatures at Sea Lion Landing, and finally learn the secrets of beer at Columbia Brew Bus.

To see photos, more things to do, where to stay, and more tourist information, read our Columbia journey builder site.

You can drive from Greenville to Columbia in 2 hours. Another option is to take a bus. May in Columbia sees daily highs of 84°F and lows of 62°F at night. Wrap up your sightseeing on the 10th (Mon) to allow time to drive to Hilton Head.

Things to do in Columbia

Zoos & Aquariums · Parks · Tours · Breweries & Distilleries

Hilton Head

— 3 nights
A Hilton Head vacation may be heaven for a golfer, but the area also offers all kinds of other options for sports fans.
Hilton Head is known for wildlife, beaches, and adventure. Your plan includes some of its best attractions: get up close to creatures of the deep with a dolphin and whale watching tour, identify plant and animal life at Pinckney Island National Wildlife Refuge, awaken your taste buds at Carolina Tasting Room, and indulge in some personalized pampering at some of the best spas.

To see other places to visit, where to stay, and tourist information, use the Hilton Head trip itinerary planning tool.

Traveling by car from Columbia to Hilton Head takes 3 hours. Alternatively, you can do a combination of train and taxi; or fly. In May, daily temperatures in Hilton Head can reach 80°F, while at night they dip to 66°F. Finish your sightseeing early on the 13th (Thu) to allow enough time to drive to Beaufort.

Things to do in Hilton Head

Parks · Outdoors · Wildlife · Historic Sites

Side Trip

Beaufort

— 2 nights
Beaufort is a city in and the county seat of Beaufort County, South Carolina, United States. Start off your visit on the 14th (Fri): take a stroll through The Point, stroll around Henry C. Chambers Waterfront Park, then examine the collection at Pat Conroy Literary Center, and finally settle in for a delightful tour with a horse-drawn carriage tour. Get ready for a full day of sightseeing on the next day: admire the majestic nature at Hunting Island State Park, then make a trip to Bay Street, and then don't miss a visit to Charles Street Gallery.

To find ratings, reviews, traveler tips, and more tourist information, refer to the Beaufort road trip app.

Traveling by car from Hilton Head to Beaufort takes an hour. Alternatively, you can take a bus. In May, plan for daily highs up to 81°F, and evening lows to 65°F. Wrap up your sightseeing on the 15th (Sat) to allow time to drive to Charleston.

Things to do in Beaufort

Parks · Nature · Neighborhoods · Historic Sites

Charleston

— 5 nights
Many visitors describe their Charleston holiday as a warm embrace by an old, dear friend--who lived about 200 years ago.
Charleston is known for parks, historic sites, and shopping. Your plan includes some of its best attractions: take in nature's colorful creations at Magnolia Plantation & Gardens, get interesting insight from Tours, get thoroughly spooked out with a ghost and vampire tour, and hunt for treasures at Charleston City Market.

For maps, reviews, and more tourist information, refer to the Charleston trip itinerary planning site.

Drive from Beaufort to Charleston in 1.5 hours. Alternatively, you can take a bus. May in Charleston sees daily highs of 81°F and lows of 64°F at night. Wrap up your sightseeing on the 20th (Thu) early enough to drive to Myrtle Beach.

Things to do in Charleston

Historic Sites · Parks · Museums · Tours

Side Trips

Myrtle Beach

— 3 nights
Myrtle Beach is a coastal city on the east coast of the United States in Horry County, South Carolina. Explore Myrtle Beach's surroundings by going to Brookgreen Gardens (in Murrells Inlet) and Prince George Winyah Episcopal Church (in Georgetown). There's much more to do: observe the fascinating underwater world at Ripley's Aquarium of Myrtle Beach, get a dose of the wild on a nature and wildlife tour, sample the tasty concoctions at New South Brewing, and examine the collection at Myrtle Beach Pinball Museum.

For where to stay, more things to do, maps, and other tourist information, refer to the Myrtle Beach travel route planner.

Drive from Charleston to Myrtle Beach in 2.5 hours. Alternatively, you can take a bus. Expect a daytime high around 79°F in May, and nighttime lows around 64°F. Wrap up your sightseeing on the 23rd (Sun) to allow time to travel back home.

Things to do in Myrtle Beach

Parks · Museums · Outdoors · Fun & Games

Side Trips

South Carolina travel guide

4.3
Historic Sites · Dolphin & Whale Watching · Gardens
The Palmetto State
Composed of five distinct geographic regions with boundaries roughly parallel to the Atlantic coastline, South Carolina embraces rich history, scenic beauty, and outstanding cuisine. Originally established as a slave society dependent on the cultivation of rice and indigo, the state now boasts a diverse economy that includes massive production of textile goods, chemical products, machinery, and automobiles. Widely regarded as the beginning of the Deep South, the state remains a deeply conservative part of the country, fervently clinging to its religious and cultural traditions. South Carolinians are kind and open hosts to those who vacation here, eager to share the wealth of their cultural heritage with curious visitors. With many remarkable places to visit like Charleston and Hilton Head, your itinerary here is sure to be diverse and full of scenic attractions.