16 days in South Carolina Itinerary

16 days in South Carolina Itinerary

Created using Inspirock South Carolina tour itinerary planner

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Route & dates

16 days in South Carolina Itinerary

Start: Cincinnati
Fly:  2​h 45​min
1
Myrtle Beach
— 2 nights
Drive:  2​h 15​min
2
Charleston
— 5 nights
Drive:  2​h 15​min
3
Hilton Head
— 3 nights
Drive:  3​h
4
Columbia
— 2 nights
bus:  1​h 30​min
5
Greenville
— 3 nights
taxi + Fly:  5​h 30​min
End: Cincinnati

2
nights
Myrtle Beach

Myrtle Beach ©
Myrtle Beach is a coastal city on the east coast of the United States in Horry County, South Carolina. You'll find plenty of places to visit near Myrtle Beach: Brookgreen Gardens (in Murrells Inlet) and Prince George Winyah Episcopal Church (in Georgetown). And it doesn't end there: shop like a local with Broadway at the Beach, stroll through Myrtle Beach, take a leisurely stroll along Myrtle Beach Boardwalk & Promenade, and catch some excitement at Myrtle Beach SkyWheel.

For other places to visit, more things to do, and tourist information, go to the Myrtle Beach road trip site .

Cincinnati to Myrtle Beach is an approximately 3-hour flight. You can also do a combination of bus and flight; or drive. Traveling from Cincinnati in October, things will get a bit warmer in Myrtle Beach: highs are around 76°F and lows about 59°F. Finish your sightseeing early on the 5th (Sat) so you can drive to Charleston.

Things to do in Myrtle Beach

Parks Outdoors Museums

Side Trips

Brookgreen Gardens, Prince George Winyah Episcopal Church
Highlights from your plan
Broadway at the Beach ©
Broadway at the Beach
Myrtle Beach SkyWheel ©
Myrtle Beach SkyWheel
Ripley's Aquarium of Myrtle Beach ©

5
nights
Charleston

Many visitors describe their Charleston holiday as a warm embrace by an old, dear friend--who lived about 200 years ago.
Charleston is known for historic sites, parks, shopping, nightlife, and museums. Your plan includes some of its best attractions: admire the natural beauty at Magnolia Plantation & Gardens, contemplate the long history of Middleton Place, take in the local highlights with Walking tours, and get thoroughly spooked out with a ghost and vampire tour.

To see other places to visit, more things to do, photos, and other tourist information, use the Charleston day trip planning app .

You can drive from Myrtle Beach to Charleston in 2.5 hours. Another option is to take a bus. In October, plan for daily highs up to 78°F, and evening lows to 60°F. Finish your sightseeing early on the 10th (Thu) to allow enough time to drive to Hilton Head.

Things to do in Charleston

Historic Sites Parks Tours

Side Trip

H. L. Hunley
Highlights from your plan
Horse-Drawn Carriage Tours
Magnolia Plantation & Gardens ©
Magnolia Plantation & Gardens
Fort Sumter National Monument ©
Fort Sumter National Monument

3
nights
Hilton Head

A Hilton Head vacation may be heaven for a golfer, but the area also offers all kinds of other options for sports fans.
Explore Hilton Head's surroundings by going to Beaufort (Henry C. Chambers Waterfront Park, Pat Conroy Literary Center, & more). There's much more to do: get up close to creatures of the deep with a dolphin and whale watching tour, get some thrills out on the water with a waterskiing or jet-skiing adventure, tour the pleasant surroundings at Coligny Beach, and trek along Hilton Head Island Bike Trails.

To see more things to do, photos, other places to visit, and other tourist information, use the Hilton Head visit website .

You can drive from Charleston to Hilton Head in 2.5 hours. Alternatively, you can take a bus. In October, plan for daily highs up to 78°F, and evening lows to 62°F. Finish your sightseeing early on the 13th (Sun) so you can drive to Columbia.

Things to do in Hilton Head

Outdoors Parks Tours

Side Trip

Beaufort
Highlights from your plan
Waterskiing & Jetskiing
Dolphin & Whale Watching
Hilton Head Island Bike Trails ©
Hilton Head Island Bike Trails

2
nights
Columbia

Columbia ©
A compact capital with stately southern history, Columbia serves as a symbol of the south.
Start off your visit on the 14th (Mon): stroll through Cayce Riverwalk, test your team's savvy at popular escape rooms, and then get to know the resident critters at Riverbanks Zoo and Botanical Garden. Keep things going the next day: look for all kinds of wild species at Congaree Creek Heritage Preserve, then tour the pleasant surroundings at Timmerman Trail, then meet the residents at Sea Lion Landing, and finally explore the different monuments and memorials at Elmwood Cemetery.

For reviews, more things to do, and more tourist information, read Columbia travel planner.

You can drive from Hilton Head to Columbia in 3 hours. Other options are to do a combination of taxi and train; or take a bus. Traveling from Hilton Head in October, plan for slightly colder nights in Columbia, with lows around 56°F. Finish your sightseeing early on the 15th (Tue) to allow enough time to take a bus to Greenville.

Things to do in Columbia

Parks Zoos & Aquariums Trails

Side Trip

Cayce
Highlights from your plan
Riverbanks Zoo and Botanical Garden ©
Congaree Creek Heritage Preserve ©
Congaree Creek Heritage Preserve
Timmerman Trail ©
Timmerman Trail

3
nights
Greenville

Greenville ©
The largest city in "upstate" South Carolina, Greenville has grown around the natural wonders of waterfalls located in the downtown area.
Step out of Greenville to go to Seneca and see Twin Lakes Park, which is approximately 56 minutes away. There's lots more to do: admire the sheer force of Falls Park on the Reedy, snap pictures at Liberty Bridge, get a taste of the local shopping with TD Saturday Market, and head outdoors with Mice on Main.

For maps, other places to visit, where to stay, and other tourist information, you can read our Greenville trip planner .

You can take a bus from Columbia to Greenville in 1.5 hours. Alternatively, you can drive. Expect a daytime high around 75°F in October, and nighttime lows around 54°F. Finish your sightseeing early on the 18th (Fri) to allow enough time to travel back home.

Things to do in Greenville

Parks Nature Wildlife

Side Trips

Suber's Mill, Twin Lakes Park
Highlights from your plan
Falls Park on the Reedy ©
Falls Park on the Reedy
Craft Axe Throwing- Greenville ©
Craft Axe Throwing- Greenville
Dark Corner Distillery ©
Dark Corner Distillery

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