16 days in United States Itinerary

San Francisco is a top holiday destination featuring scenic beauty and great ethnic and cultural diversity.

On the 2nd (Thu), see the interesting displays at de Young Museum, don't miss a visit to Golden Gate Bridge, then take a leisurely stroll along Fisherman's Wharf, and finally head off the coast to Alcatraz Island. On the 3rd (Fri), you'll have a packed day of sightseeing: take in nature's colorful creations at Japanese Tea Garden, take an exotic tour of Point Reyes Safaris, then don't miss a visit to Lombard Street, and finally browse the different shops at Ferry Building Marketplace.

To see traveler tips, other places to visit, where to stay, and other tourist information, read San Francisco trip planner.

Newark to San Francisco is an approximately 7-hour flight. You can also drive; or do a combination of bus, train, and subway. The time zone changes from Eastern Standard Time to Pacific Standard Time, which is usually a -3 hour difference. In March, San Francisco is a bit warmer than Newark - with highs of 65°F and lows of 50°F. Wrap up your sightseeing on the 3rd (Fri) to allow time to fly to Las Vegas.

Nicknamed the "Entertainment Capital of the World," Las Vegas sits in the middle of a desert in the southern section of Nevada.

Kick off your visit on the 4th (Sat): get a taste of the local shopping with The Strip, then try your luck at Bellagio Hotel and Casino, and then take in breathtaking views at Red Rock Canyon National Conservation Area. On your second day here, try to win big at Casino At The Venetian, take in nature's colorful creations at Bellagio Conservatory & Botanical Gardens, ponder the design of Fountains of Bellagio, buy something for everyone on your list at The Grand Canal Shoppes at The Venetian Resort, then see the interesting displays at The Neon Museum, and finally see the interesting displays at The Mob Museum.

For reviews, more things to do, traveler tips, and tourist information, use the Las Vegas road trip tool.

Fly from San Francisco to Las Vegas in 3 hours. Alternatively, you can drive; or do a combination of subway, train, and bus. Traveling from San Francisco in March, expect nights in Las Vegas to be about the same, around 52°F, while days are somewhat warmer, around 74°F. Finish your sightseeing early on the 5th (Sun) so you can fly to Everglades National Park.

A vast expanse of pristine wetlands, Everglades National Park holds the distinction of being the largest tropical wilderness in the U.S. Overflow from Lake Okeechobee into the Florida Bay formed these wetlands, which are home to manatees, American crocodiles, Florida panthers, and an array of wading birds, land birds, and birds of prey.

Kick off your visit on the 6th (Mon): explore the activities along Slough Slog, then identify plant and animal life at Shark Valley Visitor Center, and then tour the pleasant surroundings at 99 Mile Wilderness Waterway. Get ready for a full day of sightseeing on the next day: identify plant and animal life at Mahogany Hammock, identify plant and animal life at Nine Mile Pond Canoe Trail, contemplate the long history of Nike Missile Site HM-69, then identify plant and animal life at Anhinga Trail, and finally trek along Gumbo Limbo Trail.

For maps, ratings, and other tourist information, read our Everglades National Park trip planner.

Fly from Las Vegas to Everglades National Park in 6.5 hours. Alternatively, you can do a combination of bus and train; or do a combination of bus and train. The time zone difference when traveling from Las Vegas to Everglades National Park is 3 hours. Plan for a bit warmer temperatures traveling from Las Vegas in March, with highs in Everglades National Park at 81°F and lows at 69°F. Wrap up your sightseeing on the 7th (Tue) to allow time to fly to Key West.

Located just 140 km (90 mi) from Cuba, Key West is an island only about 6.4 km (4 mi) long and 1.6 km (1 mi) wide.

Explore Key West's surroundings by going to National Key Deer Refuge (in Big Pine Key), Marathon (Crane Point Museum & Nature Center & The Turtle Hospital) and Angelic Moon Holistic Day Spa & APOTHECARY (in Cudjoe Key). Next up on the itinerary: look for all kinds of wild species at Key West Butterfly & Nature Conservatory, explore the gorgeous colors at Vandenberg Wreck, examine the collection at Mel Fisher Maritime Heritage Museum, and steep yourself in history at Truman Little White House.

For photos, reviews, other places to visit, and other tourist information, you can read our Key West journey planner.

You can fly from Everglades National Park to Key West in 2.5 hours. Alternatively, you can take a bus; or take a bus. March in Key West sees daily highs of 79°F and lows of 69°F at night. Finish your sightseeing early on the 10th (Fri) to allow enough time to drive to Key Largo.

The northernmost island of the Florida Keys, Key Largo provides stunning scenery, a number of watersports opportunities, and plenty of areas to relax on vacation.

On the 11th (Sat), get a dose of the wild on Capt. Sterling's Everglades Eco-Tours, look for all kinds of wild species at Molasses Reef, then see what you can catch with Florida Keys Flats Fishing, and finally look for all kinds of wild species at Florida Keys Wild Bird Rehabilitation Center. On your second day here, stroll through Spiegel Grove, explore the gorgeous colors at Grecian Rocks, then look for all kinds of wild species at North Dry Rocks, and finally see the vivid underwater world at Key Largo Dry Rocks.

For where to stay, other places to visit, more things to do, and more tourist information, read our Key Largo route maker app.

Traveling by car from Key West to Key Largo takes 2.5 hours. Alternatively, you can take a bus. Traveling from Key West in March, plan for a bit cooler nights in Key Largo, with lows around 63°F. Finish your sightseeing early on the 12th (Sun) to allow enough time to fly to Washington DC.

The capital of the United States, the District of Columbia contains the lion's share of the country's most treasured monuments, memorials, and public museums.

Kick off your visit on the 13th (Mon): pause for some photo ops at Lincoln Memorial, pause for some photo ops at Vietnam Veterans Memorial, take an in-depth tour of United States Holocaust Memorial Museum, learn more about the world around you at Smithsonian National Museum of Natural History, then see the interesting displays at National Air and Space Museum, and finally appreciate the history behind Jefferson Memorial. Keep things going the next day: explore the activities along Tidal Basin, pause for some photo ops at Washington Monument, get a sense of history and politics at Library of Congress, then ponder the world of politics at United States Capitol, then explore the world behind art at National Gallery of Art, and finally ponder the world of politics at White House.

To see maps, where to stay, more things to do, and other tourist information, go to the Washington DC trip planning website.

Fly from Key Largo to Washington DC in 4.5 hours. Alternatively, you can drive; or do a combination of bus and taxi. Prepare for much colder weather when traveling from Key Largo in March: high temperatures in Washington DC hover around 55°F and lows are around 37°F. Finish your sightseeing early on the 14th (Tue) to allow enough time to fly to New York City.

Writer Pearl Buck once called New York City “a place apart,” and this giant urban center remains unlike any other in the world.

New York City is known for sightseeing, museums, and nightlife. Your trip includes some of its best attractions: take in the pleasant sights at Central Park, appreciate the history behind Statue of Liberty National Monument, take in panoramic vistas at Empire State Building, and stroll around The High Line.

To find other places to visit, where to stay, and tourist information, read our New York City trip site.

Fly from Washington DC to New York City in 3 hours. Alternatively, you can take a train; or drive. When traveling from Washington DC in March, plan for a bit cooler days in New York City, with highs around 49°F, while nights are about the same with lows around 35°F. Cap off your sightseeing on the 17th (Fri) early enough to go by car back home.