17 days in South Carolina Itinerary

17 days in South Carolina Itinerary

Created using Inspirock South Carolina travel planner

Make it your trip
Fly
1
Greenville
— 1 night
Drive
2
Columbia
— 2 nights
Drive
3
Hilton Head
— 3 nights
Drive
4
Beaufort
— 2 nights
Drive
5
Charleston
— 5 nights
Drive
6
Myrtle Beach
— 3 nights
Fly

S M T W T F S
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Greenville

— 1 night

Textile Center of the World

The largest city in "upstate" South Carolina, Greenville has grown around the natural wonders of waterfalls located in the downtown area.
Start off your visit on the 8th (Wed): sample the fine beverages at Dark Corner Distillery, stop by M.Judson Booksellers & Storytellers, and then have some family-friendly fun at Craft Axe Throwing- Greenville. On the 9th (Thu), you'll have a packed day of sightseeing: experience rural life at Southern Hills Lavender, grab your bike and head to GHS Swamp Rabbit Trail, then admire the sheer force of Falls Park on the Reedy, and finally snap pictures at Liberty Bridge.

For photos, ratings, traveler tips, and other tourist information, you can read our Greenville trip planning app.

Philadelphia to Greenville is an approximately 4-hour flight. You can also drive; or take a bus. Traveling from Philadelphia in April, things will get a bit warmer in Greenville: highs are around 74°F and lows about 53°F. Finish your sightseeing early on the 9th (Thu) to allow enough time to drive to Columbia.

Things to do in Greenville

Parks · Trails · Outdoors · Nature

Side Trip

Columbia

— 2 nights

Capital of Southern Hospitality

A compact capital with stately southern history, Columbia serves as a symbol of the south.
Start off your visit on the 10th (Fri): learn about wildlife with up-close encounters at Riverbanks Zoo and Botanical Garden, test your team's savvy at The Final Door Escape Room Columbia, and then have some family-friendly fun at Craft Axe Throwing- Columbia. Here are some ideas for day two: explore the different monuments and memorials at Elmwood Cemetery, then get up close and personal with brilliant marine life at Sea Lion Landing, then let your taste buds guide you at a local gastronomic tour, and finally admire the striking features of South Carolina State House.

To find traveler tips, reviews, where to stay, and other tourist information, go to the Columbia route planning tool.

Traveling by car from Greenville to Columbia takes 2 hours. Alternatively, you can take a bus. April in Columbia sees daily highs of 77°F and lows of 54°F at night. Cap off your sightseeing on the 11th (Sat) early enough to go by car to Hilton Head.

Things to do in Columbia

Parks · Zoos & Aquariums · Historic Sites · Fun & Games

Hilton Head

— 3 nights
A Hilton Head vacation may be heaven for a golfer, but the area also offers all kinds of other options for sports fans.
Hilton Head is known for wildlife, beaches, and adventure. Your plan includes some of its best attractions: see majestic marine mammals with a dolphin and whale watching tour, tour the pleasant surroundings at Pinckney Island National Wildlife Refuge, hike along Hilton Head Island Bike Trails, and enjoy the sand and surf at Coligny Beach.

To find out how to plan a trip to Hilton Head, use our trip itinerary maker.

Traveling by car from Columbia to Hilton Head takes 3 hours. Alternatively, you can do a combination of train and taxi; or fly. In April in Hilton Head, expect temperatures between 74°F during the day and 59°F at night. Wrap up your sightseeing on the 14th (Tue) to allow time to drive to Beaufort.

Things to do in Hilton Head

Parks · Wildlife · Outdoors · Historic Sites

Side Trip

Beaufort

— 2 nights
Beaufort is a city in and the county seat of Beaufort County, South Carolina, United States. Kick off your visit on the 15th (Wed): get to know the fascinating history of The Point, then don't miss a visit to Charles Street Gallery, then walk around Henry C. Chambers Waterfront Park, and finally deepen your understanding of the past and present with a heritage tour. Here are some ideas for day two: head outdoors with Outdoor Activities, then see the interesting displays at Pat Conroy Literary Center, and then immerse yourself in nature at Hunting Island State Park.

To find maps, reviews, photos, and other tourist information, read our Beaufort trip planner.

You can drive from Hilton Head to Beaufort in an hour. Another option is to take a bus. April in Beaufort sees daily highs of 75°F and lows of 58°F at night. Cap off your sightseeing on the 16th (Thu) early enough to go by car to Charleston.

Things to do in Beaufort

Parks · Tours · Outdoors · Nature

Charleston

— 5 nights
Many visitors describe their Charleston holiday as a warm embrace by an old, dear friend--who lived about 200 years ago.
Charleston is known for parks, museums, and shopping. Your plan includes some of its best attractions: take in nature's colorful creations at Magnolia Plantation & Gardens, go on a hair-raising tour with a ghost and vampire tour, explore the galleries of Nathaniel Russell House, and tour the pleasant surroundings at Middleton Place.

To see where to stay, other places to visit, traveler tips, and other tourist information, refer to the Charleston sightseeing planning app.

Drive from Beaufort to Charleston in 1.5 hours. Alternatively, you can take a bus. In April, daily temperatures in Charleston can reach 74°F, while at night they dip to 57°F. Finish your sightseeing early on the 21st (Tue) so you can drive to Myrtle Beach.

Things to do in Charleston

Historic Sites · Parks · Museums · Tours

Side Trip

Myrtle Beach

— 3 nights
Myrtle Beach is a coastal city on the east coast of the United States in Horry County, South Carolina. When in Myrtle Beach, make a side trip to see Brookgreen Gardens in Murrells Inlet, approximately Murrells Inlet away. And it doesn't end there: observe the fascinating underwater world at Ripley's Aquarium of Myrtle Beach, get a dose of the wild on a nature and wildlife tour, wander the streets of Broadway at the Beach, and explore the landscape on two wheels at Pee Dee Bicycle.

For more things to do, reviews, and tourist information, go to the Myrtle Beach online trip builder.

You can drive from Charleston to Myrtle Beach in 2.5 hours. Alternatively, you can take a bus. Expect a daytime high around 72°F in April, and nighttime lows around 56°F. Finish up your sightseeing early on the 24th (Fri) so you can catch the flight back home.

Things to do in Myrtle Beach

Parks · Outdoors · Museums · Beaches

Side Trip

South Carolina travel guide

4.3
Gardens · Dolphin & Whale Watching · Beaches
The Palmetto State
Composed of five distinct geographic regions with boundaries roughly parallel to the Atlantic coastline, South Carolina embraces rich history, scenic beauty, and outstanding cuisine. Originally established as a slave society dependent on the cultivation of rice and indigo, the state now boasts a diverse economy that includes massive production of textile goods, chemical products, machinery, and automobiles. Widely regarded as the beginning of the Deep South, the state remains a deeply conservative part of the country, fervently clinging to its religious and cultural traditions. South Carolinians are kind and open hosts to those who vacation here, eager to share the wealth of their cultural heritage with curious visitors. With many remarkable places to visit like Charleston and Hilton Head, your itinerary here is sure to be diverse and full of scenic attractions.