2 days in Murphy & Knoxville Itinerary

Murphy is a town in and the county seat of Cherokee County, North Carolina, United States. You've now added Nantahala National Forest to your itinerary. On the 26th (Fri), browse for treasures at Black & White Market, explore the striking landscape at Nantahala National Forest, and then admire the sheer force of Fire Creek Falls.

For other places to visit, more things to do, photos, and other tourist information, go to the Murphy online vacation planner.

Chicago to Murphy is an approximately 5.5-hour combination of flight and car. You can also drive; or do a combination of bus and car. Traveling from Chicago to Murphy, you'll lose 1 hour due to the time zone difference. When traveling from Chicago in March, plan for somewhat warmer days in Murphy, with highs around 59°F, while nights are about the same with lows around 35°F. You will leave for Knoxville on the 27th (Sat).

A gateway to Great Smoky Mountains National Park, Knoxville embraces music culture.

Kick off your visit on the 27th (Sat): kick your exploration up a notch at Navitat Knoxville and then do a tasting at Blue Slip Winery.

To find out how to plan a trip to Knoxville, use our trip itinerary maker.

You can drive from Murphy to Knoxville in 2.5 hours. March in Knoxville sees daily highs of 60°F and lows of 39°F at night. Finish your sightseeing early on the 27th (Sat) to allow enough time to fly back home.