20 days in Mississippi Itinerary

Tunica is a town in and the county seat of Tunica County, Mississippi, near the Mississippi River. Start off your visit on the 8th (Fri): walk around Tunica County River Park, try your luck at Hollywood Casino Tunica, and then try to win big at Sam's Town Casino. Here are some ideas for day two: try to win big at Gold Strike Casino, try to win big at Horseshoe Tunica, and then try to win big at Tunica Roadhouse Casino.

To see other places to visit and other tourist information, refer to the Tunica trip planner.

Atlanta to Tunica is an approximately 3-hour flight. You can also drive; or do a combination of bus and taxi. The time zone difference moving from Eastern Standard Time to Central Standard Time is minus 1 hour. Traveling from Atlanta in September, plan for a bit cooler nights in Tunica, with lows around 62°F. Finish up your sightseeing early on the 9th (Sat) so you can go by car to Tupelo.

Tupelo is the county seat and the largest city of Lee County, Mississippi. Explore Tupelo's surroundings by going to Oxford (Square Books, Rowan Oak, &more). There's lots more to do: explore and take pictures at Natchez Trace Parkway, test your team's savvy at popular escape rooms, contemplate the long history of Elvis Presley Birthplace & Museum, and see the interesting displays at Tupelo Automobile Museum.

To find ratings, maps, other places to visit, and more tourist information, read our Tupelo trip planner.

Traveling by car from Tunica to Tupelo takes 2.5 hours. Alternatively, you can do a combination of taxi and bus. Expect a daytime high around 87°F in September, and nighttime lows around 64°F. Finish your sightseeing early on the 12th (Tue) to allow enough time to drive to Starkville.

Starkville is a city in and the county seat of Oktibbeha County, Mississippi, United States. Kick off your visit on the 13th (Wed): play a few rounds at Old Waverly, get engrossed in the history at Cobb Museum of Archaeology, and then don't miss a visit to Mississippi State University.

For other places to visit, more things to do, ratings, and more tourist information, use the Starkville road trip planning website.

Getting from Tupelo to Starkville by car takes about 1.5 hours. In September, plan for daily highs up to 86°F, and evening lows to 63°F. Finish up your sightseeing early on the 13th (Wed) so you can go by car to Indianola.

Indianola is a city in Sunflower County, Mississippi, United States, in the Mississippi Delta. Start off your visit on the 14th (Thu): examine the collection at Highway 61 Blues Museum, take an in-depth tour of Jim Henson Exhibit, and then examine the collection at B.B. King Museum and Delta Interpretive Center.

For maps, ratings, traveler tips, and other tourist information, go to the Indianola holiday maker app.

Getting from Starkville to Indianola by car takes about 2.5 hours. September in Indianola sees daily highs of 90°F and lows of 65°F at night. Finish up your sightseeing early on the 14th (Thu) so you can go by car to Vicksburg.

Vicksburg is the only city and county seat of Warren County, Mississippi, United States. You'll find plenty of places to visit near Vicksburg: Port Gibson (Windsor Ruins & First Presbyterian Church of Port Gibson). There's still lots to do: get engrossed in the history at U.S.S. Cairo Museum, cruise along Vicksburg Campaign Trail, don't miss a visit to Vicksburg Riverfront Murals, and stroll the grounds of Vicksburg National Cemetery.

For where to stay, reviews, maps, and other tourist information, go to the Vicksburg online trip itinerary builder.

Getting from Indianola to Vicksburg by car takes about 2 hours. In September, daytime highs in Vicksburg are 88°F, while nighttime lows are 67°F. Cap off your sightseeing on the 18th (Mon) early enough to go by car to Natchez.

Natchez is the county seat and only city of Adams County, Mississippi, United States. You'll find plenty of places to visit near Natchez: Jackson (Lemuria Books, Eudora Welty House and Garden, &more). Spend the 20th (Wed) exploring nature at Melrose. There's lots more to do: make a trip to Longwood, stroll the grounds of Natchez City Cemetery, admire the natural beauty at Natchez Garden Club, and steep yourself in history at Rosalie Mansion.

Planning Natchez trip won't be overwhelming when you use Inspirock's itinerary maker.

Traveling by car from Vicksburg to Natchez takes 1.5 hours. In September, daytime highs in Natchez are 87°F, while nighttime lows are 68°F. Wrap up your sightseeing on the 22nd (Fri) to allow time to drive to Biloxi.

A busy city on the Gulf Coast, Biloxi is one of the nation's oldest communities, first settled by Europeans in 1699.

Biloxi is known for casinos, historic sites, and beaches. Your trip includes some of its best attractions: tee off at Fallen Oak Golf Course, get your game on at IP Casino Resort, explore the world behind art at Walter Anderson Museum of Art, and meet the residents at The Institute for Marine Mammal Studies.

Ask Inspirock to suggest an itinerary and make planning a trip to Biloxi fast, fun, and easy.

Traveling by car from Natchez to Biloxi takes 4.5 hours. Alternatively, you can do a combination of car, train, and bus; or do a combination of taxi and flight. In September, plan for daily highs up to 88°F, and evening lows to 72°F. Cap off your sightseeing on the 27th (Wed) early enough to catch the flight back home.