20 days in South Carolina Itinerary
Created using Inspirock South Carolina sightseeing planner
Start: Atlanta
Drive
1
Greenville
— 2 nights
Drive
2
Myrtle Beach
— 4 nights
Drive
3
Charleston
— 6 nights
Drive
4
Beaufort
— 3 nights
Drive
5
Hilton Head
— 4 nights
Fly
End: Atlanta
Thu, May 11 - Tue, May 30
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View full calendar
Greenville — 2 nights

Textile Center of the World
Venture out of the city with trips to Oconee Station State Historic Site (in Walhalla), Fred W. Symmes Chapel (in Cleveland) and Chattooga Ridge Canopy Tours (in Long Creek). There's much more to do: take in the dramatic scenery at Falls Park on the Reedy, appreciate the history behind Major Rudolph Anderson Memorial, snap pictures at Liberty Bridge, and get a taste of the local shopping with Art Crossing.
To see photos, where to stay, other places to visit, and other tourist information, use the Greenville day trip tool.
Atlanta to Greenville is an approximately 2.5-hour car ride. You can also fly; or drive; or do a combination of subway and bus. In May in Greenville, expect temperatures between 81°F during the day and 60°F at night. Finish your sightseeing early on the 13th (Sat) so you can drive to Myrtle Beach.
more
To see photos, where to stay, other places to visit, and other tourist information, use the Greenville day trip tool.
Atlanta to Greenville is an approximately 2.5-hour car ride. You can also fly; or drive; or do a combination of subway and bus. In May in Greenville, expect temperatures between 81°F during the day and 60°F at night. Finish your sightseeing early on the 13th (Sat) so you can drive to Myrtle Beach.
Side Trips
Highlights from your trip
Myrtle Beach — 4 nights

Explore the numerous day-trip ideas around Myrtle Beach: Litchfield Beach (in Litchfield Beach) and Murrells Inlet (Brookgreen Gardens & Huntington Beach State Park).
To find more things to do, traveler tips, and more tourist information, refer to the Myrtle Beach holiday planner.
Getting from Greenville to Myrtle Beach by car takes about 5 hours. Other options: fly; or take a bus. In May, plan for daily highs up to 79°F, and evening lows to 64°F. Wrap up your sightseeing on the 17th (Wed) to allow time to drive to Charleston.
more
To find more things to do, traveler tips, and more tourist information, refer to the Myrtle Beach holiday planner.
Getting from Greenville to Myrtle Beach by car takes about 5 hours. Other options: fly; or take a bus. In May, plan for daily highs up to 79°F, and evening lows to 64°F. Wrap up your sightseeing on the 17th (Wed) to allow time to drive to Charleston.
Side Trips
Highlights from your trip
Charleston — 6 nights
Charleston is known for parks, historic sites, and sightseeing. Your trip includes some of its best attractions: get a new perspective on things with Boat Tours & Water Sports, take in the views from Arthur Ravenel Jr. Bridge, settle in for a delightful tour with a horse-drawn carriage tour, and take in nature's colorful creations at Middleton Place.
To see photos, ratings, maps, and more tourist information, you can read our Charleston itinerary builder tool.
Traveling by car from Myrtle Beach to Charleston takes 2.5 hours. Alternatively, you can take a bus. Expect a daytime high around 81°F in May, and nighttime lows around 64°F. Finish your sightseeing early on the 23rd (Tue) so you can drive to Beaufort.
more
To see photos, ratings, maps, and more tourist information, you can read our Charleston itinerary builder tool.
Traveling by car from Myrtle Beach to Charleston takes 2.5 hours. Alternatively, you can take a bus. Expect a daytime high around 81°F in May, and nighttime lows around 64°F. Finish your sightseeing early on the 23rd (Tue) so you can drive to Beaufort.
Side Trip
Highlights from your trip
Beaufort — 3 nights

Beaufort is known for nature, historic sites, and parks. Your trip includes some of its best attractions: examine the collection at Pat Conroy Literary Center, explore the landscape on two wheels at Spanish Moss Trail, stroll around Henry C. Chambers Waterfront Park, and make a trip to Charles Street Gallery.
Plan a trip to Beaufort easily and quickly by telling Inspirock to suggest an itinerary.
Traveling by car from Charleston to Beaufort takes 1.5 hours. Alternatively, you can take a bus. In May, daily temperatures in Beaufort can reach 81°F, while at night they dip to 65°F. Finish up your sightseeing early on the 26th (Fri) so you can go by car to Hilton Head.
more
Plan a trip to Beaufort easily and quickly by telling Inspirock to suggest an itinerary.
Traveling by car from Charleston to Beaufort takes 1.5 hours. Alternatively, you can take a bus. In May, daily temperatures in Beaufort can reach 81°F, while at night they dip to 65°F. Finish up your sightseeing early on the 26th (Fri) so you can go by car to Hilton Head.
Highlights from your trip
Hilton Head — 4 nights
Hilton Head is known for wildlife, beaches, and adventure. Your trip includes some of its best attractions: identify plant and animal life at Wildlife Areas, hike along Hilton Head Island Bike Trails, enjoy the sand and surf at Coligny Beach, and go for a stroll along the water at Shelter Cove Harbour & Marina.
To see reviews, more things to do, photos, and tourist information, use the Hilton Head road trip app.
You can drive from Beaufort to Hilton Head in an hour. Another option is to take a bus. May in Hilton Head sees daily highs of 80°F and lows of 66°F at night. Cap off your sightseeing on the 30th (Tue) early enough to catch the flight back home.
more
To see reviews, more things to do, photos, and tourist information, use the Hilton Head road trip app.
You can drive from Beaufort to Hilton Head in an hour. Another option is to take a bus. May in Hilton Head sees daily highs of 80°F and lows of 66°F at night. Cap off your sightseeing on the 30th (Tue) early enough to catch the flight back home.
Side Trip
Highlights from your trip
South Carolina travel guide
The Palmetto State
Composed of five distinct geographic regions with boundaries roughly parallel to the Atlantic coastline, South Carolina embraces rich history, scenic beauty, and outstanding cuisine. Originally established as a slave society dependent on the cultivation of rice and indigo, the state now boasts a diverse economy that includes massive production of textile goods, chemical products, machinery, and automobiles. Widely regarded as the beginning of the Deep South, the state remains a deeply conservative part of the country, fervently clinging to its religious and cultural traditions. South Carolinians are kind and open hosts to those who vacation here, eager to share the wealth of their cultural heritage with curious visitors. With many remarkable places to visit like Charleston and Hilton Head, your itinerary here is sure to be diverse and full of scenic attractions.