21 days in North Carolina Itinerary

21 days in North Carolina Itinerary

Created using Inspirock North Carolina trip itinerary planner

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Route & dates

21 days in North Carolina Itinerary

Start: Louisville
Fly + Drive:  6​h
1
Cherokee
— 3 nights
Drive:  1​h 15​min
2
Asheville
— 5 nights
Fly:  5​h
3
Wilmington
— 3 nights
Drive + ferry:  5​h 15​min
4
Ocracoke
— 3 nights
Drive:  2​h 45​min
5
Kill Devil Hills
— 5 nights
Drive + Fly:  6​h 45​min
End: Louisville

3
nights
Cherokee

The center of Cherokee culture in the eastern part of the country, the town named after this Native American tribe serves as a base camp for hiking in the Great Smoky Mountains.
Your cultural itinerary includes sights like Wheels Through Time Transportation Museum and Museum of the Cherokee Indian. Let the collections at World Methodist Museum and It's By Nature capture your imagination. Explore the numerous day-trip ideas around Cherokee: Elevated Mountain Distilling Co. (in Maggie Valley), Dry Falls (in Highlands) and The Strand at 38 Main (in Waynesville). There's still lots to do: let the river carry you with a rafting and tubing tour, take in the dramatic scenery at Mingo Falls, take in the awesome beauty at Whiteside Mountain, and try to win big at Casino at Harrah’s Cherokee.

To see more things to do, maps, photos, and more tourist information, go to the Cherokee route planner.

Louisville to Cherokee is an approximately 6-hour combination of flight and car. You can also drive; or do a combination of bus and taxi. Expect little chillier evenings in Cherokee when traveling from Louisville in May, with lows around 49°F. Wrap up your sightseeing on the 30th (Thu) to allow time to drive to Asheville.

Things to do in Cherokee

Nature Parks Museums

Side Trips

Maggie Valley, The Strand at 38 Main, It's By Nature, Dry Falls, Whiteside Mountain
Highlights from your plan
River Rafting & Tubing
Dry Falls ©
Dry Falls

5
nights
Asheville

Asheville nestles between two major mountain ranges in the scenic western section of North Carolina.
Get some historical perspective at Basilica of Saint Lawrence and Biltmore Village. Appreciate the collections at Southern Highland Craft Guild Folk Art Center and Colin's Creatures. You'll find plenty of places to visit near Asheville: Saint Paul Mountain Vineyards (in Hendersonville), Chimney Rock at Chimney Rock State Park (in Chimney Rock) and DuPont State Recreational Forest (in Cedar Mountain). Next up on the itinerary: shop like a local with Philip DeAngelo Studio, take in the exciting artwork at Lexington Glassworks, explore the wealth of natural beauty at The North Carolina Arboretum, and savor the flavors at Food & Drink.

To see where to stay, photos, and tourist information, read our Asheville vacation builder app .

You can drive from Cherokee to Asheville in 1.5 hours. Alternatively, you can do a combination of taxi and bus. In May in Asheville, expect temperatures between 75°F during the day and 53°F at night. Cap off your sightseeing on the 4th (Tue) early enough to travel to Wilmington.

Things to do in Asheville

Outdoors Parks Tours

Side Trips

Sierra Nevada Brewing Co. Tours & Tastings, DuPont State Recreational Forest, Chimney Rock at Chimney Rock State Park, Zipline, Blue Ridge Pkwy
Highlights from your plan
Zipline
Blue Ridge Pkwy ©
Blue Ridge Pkwy
DuPont State Recreational Forest ©

3
nights
Wilmington

Wilmington ©
Holiday in Willington to discover a charming coastal city filled with azalea gardens, historical neighborhoods, and cozy cafes.
Battleship North Carolina and Noni Bacca Winery are good opportunities to explore the local culture. Step out of the city life by going to Wrightsville Beach Municipal Complex and Holden Beach. Go for a jaunt from Wilmington to Oak Island to see Oak Island Beach about 50 minutes away. There's much more to do: steep yourself in history at Airlie Gardens, wander the streets of Historic District, and sample the tasty concoctions at Broomtail Craft Brewery.

To find other places to visit, maps, traveler tips, and other tourist information, go to the Wilmington trip planner .

You can fly from Asheville to Wilmington in 5 hours. Alternatively, you can drive; or take a bus. Traveling from Asheville in June, Wilmington is a bit warmer at night with lows of 70°F. Wrap up your sightseeing on the 7th (Fri) to allow time to travel to Ocracoke.

Things to do in Wilmington

Parks Outdoors Beaches

Side Trips

Oak Island Beach, Wrightsville Beach Municipal Complex, Holden Beach
Highlights from your plan
Wrightsville Beach Municipal Complex ©
Holden Beach ©
Holden Beach
Noni Bacca Winery ©
Noni Bacca Winery

3
nights
Ocracoke

Ocracoke ©
Ocracoke is a census-designated place (CDP) and unincorporated town located at the southern end of Ocracoke Island, located entirely within Hyde County, North Carolina. Appreciate the collections at North Carolina Maritime Museum and Blue Pelican Gallery. Visit Cape Hatteras Lighthouse and Fort Ocracoke Monument for their historical value. Explore the numerous day-trip ideas around Ocracoke: Frisco Beach (in Frisco), Fort Macon State Park (in Atlantic Beach) and Island Express Ferry Service (in Beaufort). The adventure continues: enjoy the sand and surf at Ocracoke Lifeguarded Beach, stroll through Ocracoke Beach, and enjoy the sea views from Ocracoke Lighthouse.

For other places to visit, maps, reviews, and tourist information, you can read our Ocracoke itinerary planning website .

Traveling by combination of car and ferry from Wilmington to Ocracoke takes 5.5 hours. Alternatively, you can do a combination of bus and ferry. Expect little chillier weather when traveling from Wilmington in June: highs in Ocracoke hover around 83°F, while lows dip to 71°F. Wrap up your sightseeing on the 11th (Tue) early enough to drive to Kill Devil Hills.

Things to do in Ocracoke

Parks Outdoors Beaches

Side Trips

Beaufort, Blue Pelican Gallery, Frisco Beach, Cape Hatteras Lighthouse, Fort Macon State Park
Highlights from your plan
Island Express Ferry Service ©
Island Express Ferry Service
Cape Hatteras Lighthouse ©
Cape Hatteras Lighthouse
Ocracoke Lifeguarded Beach ©
Ocracoke Lifeguarded Beach

5
nights
Kill Devil Hills

Kill Devil Hills ©
Kill Devil Hills is a town in Dare County, North Carolina. Relax by the water at Carova Beach and Coquina Beach. Satisfy your inner culture vulture at Wright Brothers National Memorial and Bodie Island Lighthouse. Venture out of the city with trips to Corolla (Currituck Beach, Currituck Beach Lighthouse and Museum, & more) and Pea Island National Wildlife Refuge (in Rodanthe). Spend the 16th (Sun) exploring nature at Fort Raleigh National Historic Site. There's lots more to do: take in the exciting artwork at The Bird Store - The Outer Banks Wildlife Gallery, get some thrills out on the water with a waterskiing or jet-skiing adventure, admire the majestic nature at Jockey's Ridge State Park, and take a leisurely stroll along Duck Town Boardwalk.

For reviews, more things to do, maps, and tourist information, use the Kill Devil Hills trip planner .

Traveling by car from Ocracoke to Kill Devil Hills takes 3 hours. In June, daily temperatures in Kill Devil Hills can reach 83°F, while at night they dip to 70°F. Wrap up your sightseeing on the 16th (Sun) to allow time to travel back home.

Things to do in Kill Devil Hills

Parks Outdoors Beaches

Side Trips

Nags Head, Corolla, Pea Island National Wildlife Refuge, Fort Raleigh National Historic Site, Coquina Beach
Highlights from your plan
Wright Brothers National Memorial ©
Wright Brothers National Memorial
Jockey's Ridge State Park ©
Jockey's Ridge State Park
Bodie Island Lighthouse ©
Bodie Island Lighthouse

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