21 days in United States Itinerary

21 days in United States Itinerary

Created using Inspirock United States route builder

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Route & dates

21 days in United States Itinerary

Start: Los Angeles
Fly:  3​h 45​min
1
San Francisco
— 3 nights
Fly:  3​h 45​min
2
Los Angeles
— 6 nights
Fly:  4​h
3
Las Vegas
— 3 nights
Fly:  4​h
4
Amarillo
— 1 night
Fly:  4​h
5
Houston
— 3 nights
Fly:  5​h 45​min
6
Washington DC
— 2 nights
Fly:  3​h 45​min
End: Chicago

3
nights
San Francisco

San Francisco ©
San Francisco is a top holiday destination featuring scenic beauty and great ethnic and cultural diversity.
Alcatraz Island and Exploratorium are good opportunities to explore the local culture. Let the collections at SS Jeremiah O'Brien and Cable Car Museum capture your imagination. Venture out of the city with trips to Safari West (in Santa Rosa) and Armstrong Redwood State Reserve (in Guerneville). It doesn't end there: take in the views from Golden Gate Bridge.

For ratings, more things to do, maps, and other tourist information, refer to the San Francisco tour itinerary planner.

Los Angeles to San Francisco is an approximately 4-hour flight. You can also do a combination of flight and train; or drive. Expect slightly colder temperatures when traveling from Los Angeles in September; daily highs in San Francisco reach 28°C and lows reach 17°C. Wrap up your sightseeing on the 6th (Fri) to allow time to travel to Los Angeles.

Things to do in San Francisco

Parks Wildlife Nature

Side Trips

Armstrong Redwood State Reserve, Safari West
Highlights from your plan
Armstrong Redwood State Reserve ©
Armstrong Redwood State Reserve
Golden Gate Bridge ©
Golden Gate Bridge
Alcatraz Island ©
Alcatraz Island

6
nights
Los Angeles

Los Angeles ©
Surrounded by mountain ranges, forests, valleys, beaches, and deserts, the metropolitan area of Los Angeles is home to over 17 million people.
Museum-lovers will appreciate The Getty Center and Natural History Museum of Los Angeles County. Do some cultural sightseeing at Griffith Observatory and Santa Monica Pier. Venture out of the city with trips to Dolphin & Whale Watching (in Dana Point) and Annenberg Community Beach House (in Santa Monica). And it doesn't end there: explore the world behind art at Los Angeles County Museum of Art, browse the exhibits of La Brea Tar Pits and Museum, see the interesting displays at The Nethercutt Collection, and get engrossed in the history at Museum of Tolerance.

To find other places to visit, where to stay, maps, and other tourist information, read our Los Angeles road trip app .

Getting from San Francisco to Los Angeles by flight takes about 4 hours. Other options: do a combination of train and flight; or drive. Expect somewhat warmer temperatures when traveling from San Francisco in September; daily highs in Los Angeles reach 34°C and lows reach 22°C. Wrap up your sightseeing on the 12th (Thu) early enough to travel to Las Vegas.

Things to do in Los Angeles

Museums Historic Sites Childrens Museums

Side Trips

Santa Monica, Dolphin & Whale Watching
Highlights from your plan
Diorama-museum of Bhagavad-gita ©
Diorama-museum of Bhagavad-gita
Dolphin & Whale Watching
The Getty Center ©
The Getty Center

3
nights
Las Vegas

Las Vegas ©
Nicknamed the "Entertainment Capital of the World," Las Vegas sits in the middle of a desert in the southern section of Nevada.
Get some cultural insight at Titanic and Madame Tussauds - Las Vegas. Museum-lovers will appreciate The Mob Museum and Counts Kustoms. When in Las Vegas, make a side trip to see Spring Mountains Visitor Center in Mount Charleston, approximately 52 minutes away. And it doesn't end there: shop like a local with The Strip, explore the stunning scenery at Red Rock Canyon National Conservation Area, examine the collection at Pinball Hall of Fame, and admire the local landmark of Bellagio Fountains.

To see photos, traveler tips, and tourist information, read Las Vegas trip planner.

Traveling by flight from Los Angeles to Las Vegas takes 4 hours. Alternatively, you can drive; or take a bus. When traveling from Los Angeles in September, plan for somewhat warmer days and about the same nights in Las Vegas: temperatures range from 39°C by day to 25°C at night. Finish up your sightseeing early on the 15th (Sun) so you can travel to Amarillo.

Things to do in Las Vegas

Museums Parks Nature

Side Trip

Spring Mountains Visitor Center
Highlights from your plan
Fountains of Bellagio ©
Fountains of Bellagio
Counts Kustoms ©
Counts Kustoms
Titanic ©
Titanic

1
night
Amarillo

Amarillo ©
Known as "The Yellow Rose of Texas," Amarillo was once a series of ranches.
Start off your visit on the 16th (Mon): examine the collection at Bill's Backyard Classics, get to know the fascinating history of Lighthouse Trail, and then explore the stunning scenery at Palo Duro Canyon State Park. On the next day, admire the masterpieces at Amarillo Museum of Art, examine the collection at Jack Sisemore Traveland RV Museum, then take an in-depth tour of Panhandle-Plains Historical Museum, and finally make a trip to Second Amendment Cowboy.

Ask Inspirock to suggest an itinerary and make planning a trip to Amarillo fast, fun, and easy.

You can fly from Las Vegas to Amarillo in 4 hours. Other options are to do a combination of flight and bus; or drive. Traveling from Las Vegas to Amarillo, you'll lose 2 hours due to the time zone difference. Traveling from Las Vegas in September, things will get a bit cooler in Amarillo: highs are around 34°C and lows about 18°C. Finish your sightseeing early on the 17th (Tue) so you can travel to Houston.

Things to do in Amarillo

Museums Historic Sites Parks

Side Trip

Canyon
Highlights from your plan
Palo Duro Canyon State Park ©
Palo Duro Canyon State Park
Panhandle-Plains Historical Museum ©
Jack Sisemore Traveland RV Museum ©
Jack Sisemore Traveland RV Museum

3
nights
Houston

Houston ©
Although urban sprawl remains synonymous with Houston, most of the city's tourist attractions lie within the relatively small downtown area, surrounded by diverse neighborhoods housing the nation's biggest African-American, Asian-American, and Latino communities.
Do some cultural sightseeing at The Houston Museum of Natural Science and Museum of Fine Arts, Houston. You'll explore the less-touristy side of things at Brazoria National Wildlife Refuge and Dickinson Historical Society Depot Museum. Change things up with a short trip to Texas Wolfdog Project in Montgomery (about 1h 30 min away). There's still lots to do: engage your brain at Cockrell Butterfly Center and examine the collection at Houston Museum of African American Culture.

To find other places to visit, traveler tips, reviews, and other tourist information, read Houston trip planner .

You can fly from Amarillo to Houston in 4 hours. Alternatively, you can do a combination of bus and flight; or drive. Traveling from Amarillo in September, things will get a bit warmer in Houston: highs are around 38°C and lows about 28°C. Finish your sightseeing early on the 20th (Fri) so you can travel to Washington DC.

Things to do in Houston

Museums Parks Wildlife

Side Trips

Brazoria National Wildlife Refuge, Dickinson Historical Society Depot Museum, Texas Wolfdog Project
Highlights from your plan
Museum of Fine Arts, Houston ©
Museum of Fine Arts, Houston
The Houston Museum of Natural Science ©
Brazoria National Wildlife Refuge ©
Brazoria National Wildlife Refuge

2
nights
Washington DC

Washington DC ©
The capital of the United States, the District of Columbia contains the lion's share of the country's most treasured monuments, memorials, and public museums.
Arlington National Cemetery and George Washington's Mount Vernon will appeal to history buffs. Discover out-of-the-way places like Newseum and Steven F. Udvar-Hazy Center. There's lots more to do: examine the collection at National Air and Space Museum, take an in-depth tour of United States Holocaust Memorial Museum, learn more about the world around you at Smithsonian National Museum of Natural History, and get to know the fascinating history of Tomb of the Unknowns.

For other places to visit, more things to do, where to stay, and other tourist information, use the Washington DC online route maker .

You can fly from Houston to Washington DC in 6 hours. Other options are to do a combination of flight and train; or drive. The time zone difference when traveling from Houston to Washington DC is 1 hour. In September, Washington DC is little chillier than Houston - with highs of 32°C and lows of 21°C. Finish your sightseeing early on the 23rd (Mon) so you can travel back home.

Things to do in Washington DC

Museums Historic Sites

Side Trips

Arlington, Steven F. Udvar-Hazy Center, George Washington's Mount Vernon
Highlights from your plan
National Gallery of Art ©
National Gallery of Art
Steven F. Udvar-Hazy Center ©
Steven F. Udvar-Hazy Center
Arlington National Cemetery ©
Arlington National Cemetery

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