21 days in United States Itinerary

21 days in United States Itinerary

Created using Inspirock Florida trip planner

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Route & dates

21 days in United States Itinerary

Start: Frankfurt
Fly:  17​h
1
Titusville
— 1 night
Drive:  2​h 30​min
2
Crystal River
— 2 nights
Drive:  4​h 15​min
3
Sanibel Island
— 2 nights
Drive:  30​min
4
Fort Myers Beach
— 1 night
Drive:  1​h 15​min
5
Marco Island
— 3 nights
Ferry:  2​h 30​min
6
Key West
— 4 nights
Bus:  1​h 15​min
7
Marathon, Florida Keys
— 3 nights
Drive:  45​min
8
Islamorada
— 3 nights
Shuttle + Fly:  17​h 45​min
End: Frankfurt

1
night
Titusville

Titusville ©
America's "Space City," Titusville sits on the Indian River, just west of Kennedy Space Center, the origin point of every NASA human space flight since 1968.
You've now added NASA Kennedy Space Center Visitor Complex to your itinerary. Kick off your visit on the 20th (Fri): see the interesting displays at American Space Museum & Space Walk of Fame, then see the interesting displays at Parker Brothers Concepts, and then examine the collection at NASA Kennedy Space Center Visitor Complex. Here are some ideas for day two: contemplate the long history of Fort Christmas Historical Park and then identify plant and animal life at Orlando Wetlands Park.

To see other places to visit, photos, and tourist information, use the Titusville itinerary planner.

Frankfurt, Germany to Titusville is an approximately 17-hour flight. The time zone changes from Central European Time (CET) to Eastern Standard Time (EST), which is usually a -6 hour difference. Traveling from Frankfurt in December, things will get warmer in Titusville: highs are around 28°C and lows about 17°C. Wrap up your sightseeing on the 21st (Sat) to allow time to drive to Sanibel Island.

Things to do in Titusville

Museums Childrens Museums Wildlife

Side Trips

Christmas, NASA Kennedy Space Center Visitor Complex, Parker Brothers Concepts
Highlights from your plan
Orlando Wetlands Park ©
Orlando Wetlands Park
Parker Brothers Concepts ©
Parker Brothers Concepts

2
nights
Crystal River

The jewel of Florida's Nature Coast, Crystal River spreads around spring-fed Kings Bay, known for maintaining a constant 22 C (72 F) temperature all year long.
On the next day, pause for some photo ops at Old Homosassa Veteran's Memorial, explore the activities along Crystal River National Wildlife Refuge, and then get interesting insight from Tours.

To find where to stay, ratings, maps, and other tourist information, you can read our Crystal River trip planner .

You can drive from Titusville to Crystal River in 2.5 hours. Other options are to do a combination of train and bus; or take a bus. Traveling from Titusville in December, plan for little chillier nights in Crystal River, with lows around 13°C. Wrap up your sightseeing on the 23rd (Mon) early enough to drive to Sanibel Island.

Things to do in Crystal River

Outdoors Tours Wildlife

Side Trip

Old Homosassa Veteran's Memorial
Highlights from your plan
Scuba & Snorkeling
Crystal River National Wildlife Refuge ©
Stand-Up Paddleboarding

2
nights
Sanibel Island

Sanibel Island ©
Take a trip to Sanibel Island if you like pretty sunsets and luxurious resorts.
Kick off your visit on the 24th (Tue): see the interesting displays at The Bailey-Matthews National Shell Museum, get up close to creatures of the deep with a dolphin and whale watching tour, and then contemplate the long history of Sanibel Historical Museum and Village. Get ready for a full day of sightseeing on the next day: let the kids burn off some steam at Sanibel Community Playground, then look for all kinds of wild species at Sanibel Captiva Conservation Foundation, and then stroll through Bowman's Beach.

To find other places to visit, photos, more things to do, and tourist information, read Sanibel Island trip itinerary maker app .

You can drive from Crystal River to Sanibel Island in 4.5 hours. Alternatively, you can take a bus; or do a combination of bus and flight. Prepare for somewhat warmer weather when traveling from Crystal River in December: high temperatures in Sanibel Island hover around 31°C and lows are around 19°C. Wrap up your sightseeing on the 25th (Wed) to allow time to drive to Fort Myers Beach.

Things to do in Sanibel Island

Parks Outdoors Wildlife
Highlights from your plan
Bowman's Beach ©
Bowman's Beach
Sanibel Captiva Conservation Foundation ©

1
night
Fort Myers Beach

Fort Myers Beach is a town located on Estero Island in Lee County, Florida, United States. On the 26th (Thu), look for all kinds of wild species at Wildlife Areas, enjoy the sand and surf at Barefoot Beach Preserve, and then stop by Santini Marina Shopping Plaza.

To see more things to do, where to stay, maps, and tourist information, you can read our Fort Myers Beach trip builder app .

Fort Myers Beach is just a stone's throw from Sanibel Island. December in Fort Myers Beach sees daily highs of 31°C and lows of 19°C at night. Finish your sightseeing early on the 26th (Thu) so you can drive to Marco Island.

Things to do in Fort Myers Beach

Outdoors Wildlife Beaches

Side Trip

Barefoot Beach Preserve
Highlights from your plan
Dolphin & Whale Watching
Barefoot Beach Preserve ©
Barefoot Beach Preserve
Santini Marina Shopping Plaza ©
Santini Marina Shopping Plaza

3
nights
Marco Island

Marco Island is a city in Collier County, Florida, United States, located on an island by the same name in the Gulf of Mexico off the coast of Southwest Florida. Relax by the water at Keewaydin Island and Cape Romano. Escape the urban bustle at Waterskiing & Jetskiing and Capri Paddlecraft Park. Change things up with these side-trips from Marco Island: Everglades City (Nature & Wildlife Tours & Fishing Charters & Tours). There's still lots to do: get up close to creatures of the deep with a dolphin and whale watching tour and tour the pleasant surroundings at Winterberry Park.

For ratings, reviews, other places to visit, and other tourist information, read our Marco Island trip itinerary maker site .

Getting from Fort Myers Beach to Marco Island by car takes about 1.5 hours. Other options: take a bus. Expect a daytime high around 31°C in December, and nighttime lows around 19°C. Wrap up your sightseeing on the 29th (Sun) to allow time to ride a ferry to Key West.

Things to do in Marco Island

Outdoors Tours Wildlife

Side Trip

Everglades City
Highlights from your plan
Dolphin & Whale Watching
Nature & Wildlife Tours
Waterskiing & Jetskiing

4
nights
Key West

Key West ©
Located just 140 km (90 mi) from Cuba, Key West is an island only about 6.4 km (4 mi) long and 1.6 km (1 mi) wide.
You'll explore and learn at The Ernest Hemingway Home and Museum and U.S. Coast Guard Cutter Ingham Maritime Museum. Popular historic sites such as Key West Lighthouse and Keeper's Quarters Museum and Saint Mary Star of the Sea are in your itinerary. Next up on the itinerary: add some adventure to your tour with a kayaking and canoeing tour, explore the different monuments and memorials at Key West Cemetery, kick back and relax at Fort Zachary Taylor, and fly like a bird with a parasailing or paragliding tour.

To see ratings, traveler tips, photos, and other tourist information, refer to the Key West trip planner .

Traveling by ferry from Marco Island to Key West takes 2.5 hours. Alternatively, you can drive. Traveling from Marco Island in December, expect somewhat warmer with lows of 25°C in Key West. Finish up your sightseeing early on the 2nd (Thu) so you can catcht the bus to Marathon.

Things to do in Key West

Outdoors Parks Adventure
Highlights from your plan
Vandenberg Wreck ©
Vandenberg Wreck
Stand-Up Paddleboarding
Kayaking & Canoeing

3
nights
Marathon, Florida Keys

A tiny city just 16 km (10 mi) long, Marathon is spread across several islands in the middle of the Florida Keys.
Eschew the tourist crowds and head to Crane Point Museum & Nature Center and Sombrero Reef. Get in touch with nature at Bahia Honda State Park and Pigeon Key Foundation. And it doesn't end there: take a memorable tour with Tours, identify plant and animal life at The Turtle Hospital, find your balance on the water with some of the best stand-up paddleboarding in the area, and pause for some serene contemplation at San Pablo Catholic Church.

For photos, more things to do, where to stay, and tourist information, you can read our Marathon trip maker website .

Take a bus from Key West to Marathon in 1.5 hours. Alternatively, you can drive. In January, daytime highs in Marathon are 29°C, while nighttime lows are 22°C. Finish your sightseeing early on the 5th (Sun) to allow enough time to drive to Islamorada.

Things to do in Marathon

Wildlife Parks Outdoors

Side Trips

Bahia Honda State Park, Fishing Charters & Tours
Highlights from your plan
Fishing Charters & Tours
Crane Point Museum & Nature Center ©
Bahia Honda State Park ©
Bahia Honda State Park

3
nights
Islamorada

Islamorada ©
Islamorada, long recognized as one of the world's top spots for sport fishing, encompasses six islands in the Florida Keys.
Appreciate the collections at Old Road Gallery and Michelle Nicole Lowe Art Gallery. Take a break from the city and head to Florida Keys Wild Bird Rehabilitation Center and Anne's Beach. Next up on the itinerary: get outside with A Lil' Tail Charters, contemplate the long history of Indian Key State Historic Site, relax and rejuvenate at some of the top local wellness centers, and indulge your thirst for a good beer at Islamorada Beer Company Brewery and Tasting Room.

Make your Islamorada itinerary with Inspirock to find out what to see and where to go.

You can drive from Marathon to Islamorada in an hour. Alternatively, you can take a bus. Expect a daytime high around 29°C in January, and nighttime lows around 22°C. Cap off your sightseeing on the 8th (Wed) early enough to travel back home.

Things to do in Islamorada

Outdoors Wildlife Tours

Side Trip

Key Largo
Highlights from your plan
Dolphins Plus Marine Mammal Responder ©
Fishing Charters & Tours

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