21 days in Western US Itinerary

21 days in Western US Itinerary

Created using Inspirock Western US route planner

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Route & dates

21 days in Western US Itinerary

Start: Tampa, Florida
Fly:  7​h
1
Las Vegas
— 2 nights
Fly:  3​h 15​min
2
San Diego
— 1 night
Drive:  2​h 15​min
3
Los Angeles
— 2 nights
Fly + Drive:  4​h 15​min
4
Yosemite National Park
— 3 nights
Drive:  4​h
5
San Francisco
— 4 nights
Drive:  1​h 30​min
6
St. Helena
— 1 night
Fly:  4​h 45​min
7
Seattle
— 2 nights
Fly + Drive:  5​h 30​min
8
Yellowstone National Park
— 4 nights
Drive + Fly:  10​h
End: Tampa, Florida

2
nights
Las Vegas

Las Vegas ©
Nicknamed the "Entertainment Capital of the World," Las Vegas sits in the middle of a desert in the southern section of Nevada.
Get a sense of the local culture at The Strip and The Neon Museum. There's still lots to do: see the interesting displays at The Mob Museum, try your luck at New York New York Casino, don't miss a visit to Fountains of Bellagio, and take in panoramic vistas at Eiffel Tower Viewing Deck.

To find photos, more things to do, other places to visit, and tourist information, go to the Las Vegas trip itinerary planner.

Tampa to Las Vegas is an approximately 7-hour flight. You can also drive; or take a bus. Due to the time zone difference, you'll gain 3 hours traveling from Tampa to Las Vegas. Traveling from Tampa in September, plan for slightly colder nights in Las Vegas, with lows around 71°F. Wrap up your sightseeing on the 12th (Thu) to allow time to travel to San Diego.

Things to do in Las Vegas

Neighborhoods Shopping Historic Sites
Highlights from your plan
Fountains of Bellagio ©
Fountains of Bellagio
The Strip ©
The Strip
The Mob Museum ©
The Mob Museum

1
night
San Diego

San Diego ©
Divided into neighborhoods with distinct characters and cultural heritages, San Diego sits just north of the Mexican border and offers visitors a blend of tourist attractions, including a lively nightlife, diverse cuisine, and a thriving musical scene.
Kick off your visit on the 13th (Fri): examine the collection at USS Midway Museum and then tour the pleasant surroundings at La Jolla Cove.

For ratings, other places to visit, maps, and tourist information, read San Diego itinerary builder .

Fly from Las Vegas to San Diego in 3.5 hours. Alternatively, you can drive; or take a bus. Traveling from Las Vegas in September, expect nights in San Diego to be about the same, around 68°F, while days are little chillier, around 79°F. Wrap up your sightseeing on the 13th (Fri) to allow time to drive to Los Angeles.

Things to do in San Diego

Parks Outdoors Beaches
Highlights from your plan
La Jolla Cove ©
La Jolla Cove
USS Midway Museum ©
USS Midway Museum

2
nights
Los Angeles

Los Angeles ©
Surrounded by mountain ranges, forests, valleys, beaches, and deserts, the metropolitan area of Los Angeles is home to over 17 million people.
On the 14th (Sat), appreciate the extensive heritage of El Pueblo de Los Angeles, then see the sky in a new way at Griffith Observatory, then examine the collection at The Getty Center, and finally explore the world behind art at Los Angeles County Museum of Art. On your second day here, learn more about the world around you at La Brea Tar Pits and Museum, then learn more about the world around you at Natural History Museum of Los Angeles County, then engage your brain at California Science Center, and finally take a stroll through Angelino Heights Historic Area.

To find more things to do, photos, maps, and more tourist information, refer to the Los Angeles day trip planning app .

You can drive from San Diego to Los Angeles in 2.5 hours. Other options are to take a bus; or fly. When traveling from San Diego in September, plan for somewhat warmer days and about the same nights in Los Angeles: temperatures range from 85°F by day to 66°F at night. Finish up your sightseeing early on the 15th (Sun) so you can travel to Yosemite National Park.

Things to do in Los Angeles

Museums Childrens Museums Fun & Games
Highlights from your plan
The Getty Center ©
The Getty Center
Los Angeles County Museum of Art ©
Los Angeles County Museum of Art

3
nights
Yosemite National Park

Yosemite National Park ©
Massive granite mountains, towering waterfalls, groves of Giant Sequoia trees, and wilderness as far as the eye can see distinguish the landscape of Yosemite National Park.
Spend the 18th (Wed) on the water with a fishing tour. Next up on the itinerary: take in the dramatic natural features at Taft Point, don't miss a visit to Olmsted Point, trek along Tuolumne Meadows, and cruise along Tioga Pass.

To see ratings, reviews, other places to visit, and other tourist information, you can read our Yosemite National Park trip website .

You can do a combination of flight and car from Los Angeles to Yosemite National Park in 4.5 hours. Other options are to drive; or do a combination of flight and bus. When traveling from Los Angeles in September, plan for little chillier days in Yosemite National Park, with highs around 74°F, while nights are cooler with lows around 38°F. Finish your sightseeing early on the 18th (Wed) to allow enough time to drive to San Francisco.

Things to do in Yosemite National Park

Outdoors Parks Wildlife
Highlights from your plan
Tioga Pass ©
Tioga Pass
Olmsted Point ©
Olmsted Point
Glacier Point ©
Glacier Point

4
nights
San Francisco

San Francisco ©
San Francisco is a top holiday destination featuring scenic beauty and great ethnic and cultural diversity.
Do some cultural sightseeing at Fisherman's Wharf and Alcatraz Island. You'll explore and learn at Exploratorium and de Young Museum. Spend the 21st (Sat) exploring nature at San Francisco Maritime National Historical Park. There's much more to do: take in the views from Golden Gate Bridge, take a stroll through Twin Peaks, and get a taste of the local shopping with Union Square.

For where to stay, traveler tips, ratings, and other tourist information, read our San Francisco day trip site .

Traveling by car from Yosemite National Park to San Francisco takes 4 hours. Alternatively, you can do a combination of car and flight; or do a combination of bus and flight. Traveling from Yosemite National Park in September, San Francisco is a bit warmer at night with lows of 58°F. Finish up your sightseeing early on the 22nd (Sun) so you can go by car to St. Helena.

Things to do in San Francisco

Museums Parks Nature
Highlights from your plan
Golden Gate Bridge ©
Golden Gate Bridge
Alcatraz Island ©
Alcatraz Island
Fisherman's Wharf ©
Fisherman's Wharf

1
night
St. Helena

St. Helena ©
The city of St.
On the 23rd (Mon), learn about winemaking at Pride Mountain Vineyards, do a tasting at Anderson's Conn Valley Vineyards, then learn about winemaking at B Cellars Vineyards and Winery, then learn about winemaking at Inglenook, and finally learn about winemaking at V. Sattui Winery.

For traveler tips, reviews, where to stay, and more tourist information, read St. Helena road trip planning site .

Traveling by car from San Francisco to St. Helena takes 1.5 hours. Alternatively, you can do a combination of subway and bus; or take a bus. Traveling from San Francisco in September, expect nights in St. Helena to be a bit cooler, around 51°F, while days are a bit warmer, around 84°F. Finish your sightseeing early on the 23rd (Mon) so you can travel to Seattle.

Things to do in St. Helena

Wineries

Side Trips

Inglenook, B Cellars Vineyards and Winery
Highlights from your plan
Anderson's Conn Valley Vineyards ©
Anderson's Conn Valley Vineyards
Pride Mountain Vineyards ©
Pride Mountain Vineyards
Inglenook ©
Inglenook

2
nights
Seattle

Seattle ©
Nicknamed the "Emerald City" because of its abundant evergreen trees, Seattle is the cultural and business center of the Pacific Northwest, as well as a popular holiday destination.
Start off your visit on the 24th (Tue): see the interesting displays at The Museum of Flight, then wander the streets of Pike Place Market, then view the masterpieces at Glasshouse Studio, and finally take in panoramic vistas at Space Needle. Get ready for a full day of sightseeing on the next day: get a taste of the local shopping with Chihuly Garden and Glass, then explore the world behind art at Seattle Art Museum, and then wander the streets of Pioneer Square.

For traveler tips, where to stay, more things to do, and other tourist information, you can read our Seattle trip app .

Fly from St. Helena to Seattle in 5 hours. Alternatively, you can do a combination of bus and flight; or drive. When traveling from St. Helena in September, plan for a bit cooler days in Seattle, with highs around 72°F, while nights are about the same with lows around 56°F. Finish up your sightseeing early on the 25th (Wed) so you can travel to Yellowstone National Park.

Things to do in Seattle

Museums Shopping Neighborhoods
Highlights from your plan
Chihuly Garden and Glass ©
Chihuly Garden and Glass
The Museum of Flight ©
The Museum of Flight
Pike Place Market ©
Pike Place Market

4
nights
Yellowstone National Park

Yellowstone National Park ©
An exceptionally diverse landscape and varied wildlife have made Yellowstone National Park one of America's most popular parks.
Take a break from Yellowstone National Park with a short trip to Grand Teton in Grand Teton National Park, about 1h 25 min away. On the 29th (Sun), dedicate a day to the elevated beauty of Mount Washburn. There's much more to do: look for all kinds of wild species at Hayden Valley, hike along Brink of the Lower Falls Trail, take in the dramatic natural features at Natural Bridge Trail, and witness a stunning natural landmark at Castle Geyser.

To find out how to plan a trip to Yellowstone National Park, use our trip itinerary maker.

You can do a combination of flight and car from Seattle to Yellowstone National Park in 5.5 hours. Other options are to do a combination of flight, shuttle, and bus; or drive. Due to the time zone difference, you'll lose 1 hour traveling from Seattle to Yellowstone National Park. While traveling from Seattle, expect a bit cooler days and cooler nights in Yellowstone National Park, ranging from highs of 60°F to lows of 33°F. You'll have a few hours on the 30th (Mon) to wrap things up before traveling home.

Things to do in Yellowstone National Park

Wildlife Parks Nature

Side Trip

Grand Teton
Highlights from your plan
Grand Teton ©
Grand Teton
Hayden Valley ©
Hayden Valley
Lamar Valley ©
Lamar Valley

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