22 days in East Coast of USA Itinerary

22 days in East Coast of USA Itinerary

Created using Inspirock East Coast of USA holiday planner

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Route & dates

22 days in East Coast of USA Itinerary

Start: Tampa
bus:  3​h 15​min
1
Marco Island
— 1 night
ferry:  2​h 30​min
2
Key West
— 5 nights
bus:  1​h 15​min
3
Marathon
— 3 nights
shuttle + Fly:  6​h 45​min
4
Charleston
— 2 nights
Drive:  2​h 15​min
5
Hilton Head
— 4 nights
Drive:  2​h 30​min
6
Jekyll Island
— 2 nights
Fly:  4​h 15​min
7
Panama City Beach
— 3 nights
Drive + Fly:  5​h 30​min
End: Tampa

1
night
Marco Island

Marco Island is a city in Collier County, Florida, United States, located on an island by the same name in the Gulf of Mexico off the coast of Southwest Florida. On the 28th (Fri), get interesting insight from Tours. Here are some ideas for day two: cast your line with a fishing tour and then get up close to creatures of the deep with a dolphin and whale watching tour.

To see where to stay, reviews, traveler tips, and other tourist information, read our Marco Island trip itinerary site .

Tampa to Marco Island is an approximately 3.5-hour bus ride. You can also drive. In June, plan for daily highs up to 90°F, and evening lows to 74°F. Cap off your sightseeing on the 29th (Sat) early enough to catch the ferry to Key West.

Things to do in Marco Island

Outdoors Tours Wildlife
Highlights from your plan
Fishing Charters & Tours
Dolphin & Whale Watching
Waterskiing & Jetskiing

5
nights
Key West

Located just 140 km (90 mi) from Cuba, Key West is an island only about 6.4 km (4 mi) long and 1.6 km (1 mi) wide.
Step off the beaten path and head to Spas and U.S. Coast Guard Cutter Ingham Maritime Museum. Get in touch with nature at Key West Butterfly & Nature Conservatory and Dolphin & Whale Watching. Spend the 1st (Mon) exploring nature at Dry Tortugas National Park. Next up on the itinerary: glide through the air with a parasailing or paragliding tour, admire all the interesting features of The Overseas Highway, steep yourself in history at Truman Little White House, and see what you can catch with a fishing tour.

To see where to stay, more things to do, traveler tips, and tourist information, you can read our Key West sightseeing planning app .

Getting from Marco Island to Key West by ferry takes about 2.5 hours. Other options: drive. In June, daily temperatures in Key West can reach 88°F, while at night they dip to 79°F. Finish your sightseeing early on the 4th (Thu) to allow enough time to take a bus to Marathon.

Things to do in Key West

Outdoors Tours Wildlife
Highlights from your plan
Dolphin & Whale Watching
Scuba & Snorkeling

3
nights
Marathon

Marathon ©
A tiny city just 16 km (10 mi) long, Marathon is spread across several islands in the middle of the Florida Keys.
Discover out-of-the-way places like Scuba & Snorkeling and Dolphin Research Center. Get in touch with nature at Fishing Charters & Tours and The Turtle Hospital. There's more to do: immerse yourself in nature at Bahia Honda State Park and snap pictures at Seven Mile Bridge.

To see where to stay, photos, other places to visit, and more tourist information, use the Marathon sightseeing planning website .

Take a bus from Key West to Marathon in 1.5 hours. Alternatively, you can drive. In July, daytime highs in Marathon are 92°F, while nighttime lows are 81°F. Wrap up your sightseeing on the 7th (Sun) early enough to travel to Charleston.

Things to do in Marathon

Wildlife Outdoors Parks

Side Trips

Islamorada, Bahia Honda State Park
Highlights from your plan
Dolphin Research Center ©
Dolphin Research Center
Scuba & Snorkeling
Fishing Charters & Tours

2
nights
Charleston

Charleston ©
Many visitors describe their Charleston holiday as a warm embrace by an old, dear friend--who lived about 200 years ago.
Visiting Angel Oak Tree and Dolphin & Whale Watching will get you outdoors. Discover out-of-the-way places like Fort Moultrie and Cathedral of Saint John the Baptist. The adventure continues: indulge your taste buds at Food & Drink, stroll around Joe Riley Waterfront Park, steep yourself in history at Fort Sumter National Monument, and learn about all things military at Patriots Point.

To find traveler tips, where to stay, other places to visit, and tourist information, you can read our Charleston trip itinerary planning app .

Traveling by combination of shuttle and flight from Marathon to Charleston takes 7 hours. Alternatively, you can do a combination of bus and flight; or drive. Plan for little chillier nights when traveling from Marathon in July since evenings lows in Charleston dip to 75°F. Finish your sightseeing early on the 10th (Wed) to allow enough time to drive to Hilton Head.

Things to do in Charleston

Museums Tours Historic Sites

Side Trips

Fort Moultrie, Patriots Point, Angel Oak Tree
Highlights from your plan
Angel Oak Tree ©
Angel Oak Tree
Dolphin & Whale Watching
Fort Moultrie ©
Fort Moultrie

4
nights
Hilton Head

A Hilton Head vacation may be heaven for a golfer, but the area also offers all kinds of other options for sports fans.
Discover out-of-the-way places like Fishing Charters & Tours and Speed Boats Tours. Step out of the city life by going to Waterskiing & Jetskiing and Sea Pines Forest Preserve. There's much more to do: indulge in some personalized pampering at some of the best spas, stroll through Coligny Beach, take a tour by water with Boat Tours & Water Sports, and trek along Hilton Head Island Bike Trails.

To see more things to do, maps, reviews, and tourist information, you can read our Hilton Head day trip planner.

Traveling by car from Charleston to Hilton Head takes 2.5 hours. Alternatively, you can take a bus. Expect a daytime high around 89°F in July, and nighttime lows around 75°F. Finish your sightseeing early on the 14th (Sun) so you can drive to Jekyll Island.

Things to do in Hilton Head

Outdoors Tours Wildlife
Highlights from your plan
Fishing Charters & Tours
Speed Boats Tours
Sea Pines Forest Preserve ©
Sea Pines Forest Preserve

2
nights
Jekyll Island

Jekyll Island ©
A vacation on Jekyll Island allows visitors to discover the lifestyle of American aristocrats from the 19th century.
Kick off your visit on the 15th (Mon): look for all kinds of wild species at Georgia Sea Turtle Center and then take a stroll through Jekyll Island Historic District. Get ready for a full day of sightseeing on the next day: enjoy the sand and surf at Driftwood Beach and then get up close to creatures of the deep with a dolphin and whale watching tour.

Inspirock's itinerary builder makes planning a Jekyll Island trip simple and quick.

Traveling by car from Hilton Head to Jekyll Island takes 2.5 hours. Alternatively, you can do a combination of taxi and bus; or take a bus. In July in Jekyll Island, expect temperatures between 90°F during the day and 76°F at night. Finish your sightseeing early on the 16th (Tue) so you can travel to Panama City Beach.

Things to do in Jekyll Island

Outdoors Wildlife Parks
Highlights from your plan
Driftwood Beach ©
Driftwood Beach
Dolphin & Whale Watching
Jekyll Island Historic District ©
Jekyll Island Historic District

3
nights
Panama City Beach

Panama City Beach ©
Boasting 43 km (27 mi) of white sandy beaches and plenty of sunshine, Panama City Beach is an ideal choice for a relaxing holiday.
You'll discover tucked-away gems like Swim with Dolphins and Henderson Beach State Park. Take a break from the city and head to St. Andrews State Park and Panama City Beach. There's more to do: learn about winemaking at Panama City Beach Winery and get interesting insight from Tours.

You can plan Panama City Beach trip in no time by asking Inspirock to help create your itinerary.

Fly from Jekyll Island to Panama City Beach in 4.5 hours. Alternatively, you can drive; or do a combination of bus and flight. In July, daytime highs in Panama City Beach are 90°F, while nighttime lows are 74°F. Finish up your sightseeing early on the 19th (Fri) so you can travel back home.

Things to do in Panama City Beach

Outdoors Parks Beaches

Side Trip

Henderson Beach State Park
Highlights from your plan
St. Andrews State Park ©
St. Andrews State Park
Swim with Dolphins
Henderson Beach State Park ©
Henderson Beach State Park

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