22 days in Florida Itinerary

22 days in Florida Itinerary

Created using Inspirock Florida planner

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Route & dates

22 days in Florida Itinerary

Start: Manchester
Fly:  14​h 15​min
1
Panama City Beach
— 3 nights
+2
Drive + Fly + Bus:  6​h 30​min
2
Naples
— 3 nights
Drive:  45​min
3
Marco Island
— 2 nights
Ferry:  2​h 30​min
4
Key West
— 4 nights
Bus:  1​h 15​min
5
Marathon, Florida Keys
— 2 nights
Drive:  1​h 15​min
6
Key Largo
— 2 nights
+2
Shuttle + Fly + Drive:  5​h 15​min
7
St. Augustine
— 3 nights
Bus:  1​h
8
Daytona Beach
— 2 nights
Bus + Fly:  14​h 15​min
End: Manchester

3
nights
Panama City Beach

Panama City Beach ©
Boasting 43 km (27 mi) of white sandy beaches and plenty of sunshine, Panama City Beach is an ideal choice for a relaxing holiday.
Get a sense of the local culture at Panama City Beach Winery and Panama City CENTER for the ARTS. Step off the beaten path and head to St. Andrews State Park and Santa Rosa Beach. Take a break from Panama City Beach with a short trip to Grayton Beach State Park in Grayton Beach, about 46 minutes away. There's lots more to do: fulfill a lifelong dream with a swim-with-the-dolphins experience, get interesting insight from Tours, enjoy the sand and surf at Henderson Beach State Park, and push the limits with an extreme tour.

For maps, ratings, and more tourist information, read our Panama City Beach trip itinerary planning website .

Manchester, UK to Panama City Beach is an approximately 14.5-hour flight. You can also do a combination of flight and car; or do a combination of flight and taxi. Traveling from Manchester to Panama City Beach, you'll gain 5 hours due to the time zone difference. Expect much warmer weather when traveling from Manchester in May: highs in Panama City Beach hover around 34°C, while lows dip to 19°C. Finish your sightseeing early on the 6th (Wed) to allow enough time to travel to Naples.

Things to do in Panama City Beach

Outdoors Parks Beaches

Side Trips

Santa Rosa Beach, Panama City CENTER for the ARTS, Henderson Beach State Park, Grayton Beach State Park
Highlights from your plan
St. Andrews State Park ©
St. Andrews State Park
Grayton Beach State Park ©
Grayton Beach State Park
Henderson Beach State Park ©
Henderson Beach State Park

3
nights
Naples

Naples is a city in Collier County, Florida, United States. Head to Fifth Avenue South and Lorne's Art Galleryfor plenty of shopping. Explore hidden gems such as Lovers Key State Park and Lowdermilk Beach. Change things up with these side-trips from Naples: Sanibel Island (Bowman's Beach & Pond Apple Park), Barefoot Beach Preserve (in Bonita Springs) and Dolphin & Whale Watching (in Fort Myers Beach). There's more to do: get a new perspective on things with Boat Tours & Water Sports.

To see reviews, ratings, maps, and more tourist information, use the Naples driving holiday planner .

You can do a combination of car, flight, and bus from Panama City Beach to Naples in 6.5 hours. Other options are to do a combination of flight and bus; or drive. Traveling from Panama City Beach in May, Naples is a bit warmer at night with lows of 24°C. Wrap up your sightseeing on the 9th (Sat) to allow time to drive to Marco Island.

Things to do in Naples

Outdoors Wildlife Parks

Side Trips

Fort Myers Beach, Sanibel Island, Lorne's Art Gallery, Barefoot Beach Preserve
Highlights from your plan
Dolphin & Whale Watching
Barefoot Beach Preserve ©
Barefoot Beach Preserve
Bowman's Beach ©
Bowman's Beach

2
nights
Marco Island

Marco Island is a city in Collier County, Florida, United States, located on an island by the same name in the Gulf of Mexico off the coast of Southwest Florida. Kick off your visit on the 10th (Sun): see majestic marine mammals with a dolphin and whale watching tour, explore the activities along Capri Paddlecraft Park, and then race across the water with a speed boat tour. Get ready for a full day of sightseeing on the next day: stop by Keep In Touch, fly like a bird with a parasailing or paragliding tour, then zoom along the surf with a waterskiing or jet-skiing adventure, and finally take a tour by water with Boat Tours & Water Sports.

For photos, reviews, more things to do, and other tourist information, use the Marco Island trip maker site .

You can drive from Naples to Marco Island in an hour. May in Marco Island sees daily highs of 36°C and lows of 24°C at night. Cap off your sightseeing on the 11th (Mon) early enough to catch the ferry to Key West.

Things to do in Marco Island

Outdoors Tours Wildlife

Side Trip

Speed Boats Tours
Highlights from your plan
Dolphin & Whale Watching
Speed Boats Tours
Fishing Charters & Tours

4
nights
Key West

Located just 140 km (90 mi) from Cuba, Key West is an island only about 6.4 km (4 mi) long and 1.6 km (1 mi) wide.
Visit Key West Lighthouse and Keeper's Quarters Museum and Truman Little White House for their historical value. Visiting Scuba & Snorkeling and Dry Tortugas National Park will get you outdoors. There's still lots to do: identify plant and animal life at Wildlife Areas, brush up on your military savvy at U.S. Coast Guard Cutter Ingham Maritime Museum, paddle through the water with a kayaking and canoeing tour, and stroll the grounds of Key West Cemetery.

Plan my day in Key West using traveler tips and tourist information provided by Inspirock.

You can ride a ferry from Marco Island to Key West in 2.5 hours. Alternatively, you can drive. Traveling from Marco Island in May, you can expect nighttime temperatures to be a bit warmer in Key West, with lows of 29°C. Wrap up your sightseeing on the 15th (Fri) early enough to take a bus to Marathon.

Things to do in Key West

Outdoors Tours Wildlife
Highlights from your plan
Dolphin & Whale Watching
Kayaking & Canoeing
Scuba & Snorkeling

2
nights
Marathon, Florida Keys

Marathon ©
A tiny city just 16 km (10 mi) long, Marathon is spread across several islands in the middle of the Florida Keys.
Start off your visit on the 16th (Sat): get a new perspective on things with Boat Tours & Water Sports, identify plant and animal life at The Turtle Hospital, and then kick back and relax at Bahia Honda State Park. Get ready for a full day of sightseeing on the 17th (Sun): look for all kinds of wild species at Dolphin Research Center, then cast your line with a fishing tour, then enjoy the sand and surf at Sombrero Beach, and finally take in the exciting artwork at Shady Palm Art Gallery & Photography.

For traveler tips, photos, reviews, and more tourist information, refer to the Marathon trip site .

Traveling by bus from Key West to Marathon takes 1.5 hours. Alternatively, you can drive. In May in Marathon, expect temperatures between 36°C during the day and 29°C at night. Cap off your sightseeing on the 17th (Sun) early enough to go by car to Key Largo.

Things to do in Marathon

Parks Outdoors Wildlife

Side Trip

Bahia Honda State Park
Highlights from your plan
Dolphin Research Center ©
Dolphin Research Center
Fishing Charters & Tours
Bahia Honda State Park ©
Bahia Honda State Park

2
nights
Key Largo

Key Largo ©
The northernmost island of the Florida Keys, Key Largo provides stunning scenery, a number of watersports opportunities, and plenty of areas to relax on vacation.
Kick off your visit on the 18th (Mon): look for all kinds of wild species at Molasses Reef, identify plant and animal life at Florida Keys Wild Bird Rehabilitation Center, then stop by Robert Is Here, and finally identify plant and animal life at Anhinga Trail. Get ready for a full day of sightseeing on the 19th (Tue): get a new perspective on things with Boat Tours & Water Sports, take in the exciting artwork at Old Road Gallery, and then cast your line with a fishing tour.

To find traveler tips, where to stay, and other tourist information, use the Key Largo trip itinerary planning tool .

You can drive from Marathon to Key Largo in 1.5 hours. Alternatively, you can take a bus. Plan for little chillier nights when traveling from Marathon in May since evenings lows in Key Largo dip to 26°C. Wrap up your sightseeing on the 19th (Tue) to allow time to travel to St. Augustine.

Things to do in Key Largo

Wildlife Outdoors Tours

Side Trips

Islamorada, Anhinga Trail, Robert Is Here
Highlights from your plan
Molasses Reef ©
Molasses Reef
Anhinga Trail ©
Anhinga Trail

3
nights
St. Augustine

St. Augustine ©
SAINT AUGUSTINE | PONTE VEDRA on Florida's Historic Coast The Nation's oldest city (est. Visit Vilano Beach and St. Augustine Beach for some beach relaxation. Get some historical perspective at Fort Clinch State Park and Cathedral Basilica of St. Augustine. And it doesn't end there: explore the striking landscape of Fort Matanzas National Monument, examine the collection at The Ximenez-Fatio House, look for all kinds of wild species at St. Augustine Alligator Farm Zoological Park, and deepen your understanding at Flagler College.

Plan trip to St. Augustine with our itinerary maker to find out where to go and what to do.

Traveling by combination of shuttle, flight, and car from Key Largo to St. Augustine takes 5.5 hours. Alternatively, you can drive; or do a combination of shuttle, flight, and bus. Traveling from Key Largo in May, expect a bit cooler with lows of 22°C in St. Augustine. Finish your sightseeing early on the 22nd (Fri) to allow enough time to take a bus to Daytona Beach.

Things to do in St. Augustine

Parks Historic Sites Nature

Side Trip

Fort Clinch State Park
Highlights from your plan
Fort Clinch State Park ©
Fort Clinch State Park
Vilano Beach ©
Vilano Beach
Fort Matanzas National Monument ©
Fort Matanzas National Monument

2
nights
Daytona Beach

Daytona Beach ©
The iconic seaside destination of Daytona Beach once supported sugar mill plantations, but now entertains up to 8 million visitors a year.
Kick off your visit on the 23rd (Sat): kick back and relax at Ormond Beach, enjoy the sand and surf at Beach at Daytona Beach, then stop by Angell & Phelps Chocolate Factory, then learn about all things military at Veterans Museum & Education Center, and finally browse the exhibits of Ponce de Leon Inlet Lighthouse & Museum.

For reviews, more things to do, traveler tips, and tourist information, read Daytona Beach trip itinerary maker website .

You can take a bus from St. Augustine to Daytona Beach in an hour. Alternatively, you can drive. In May in Daytona Beach, expect temperatures between 34°C during the day and 22°C at night. Cap off your sightseeing on the 24th (Sun) early enough to travel back home.

Things to do in Daytona Beach

Parks Outdoors Beaches

Side Trips

Ormond Beach, Ponce de Leon Inlet Lighthouse & Museum
Highlights from your plan
Ormond Beach ©
Ormond Beach
Beach at Daytona Beach ©
Beach at Daytona Beach

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