22 days in Florida Keys, Nashville & Grand Canyon National Park Itinerary

Created using Inspirock United States tour planner
Make it your trip
Fly
1
Key Largo
— 2 nights
Drive
2
Islamorada
— 3 nights
Drive
3
Marathon
— 3 nights
Drive
4
Key West
— 4 nights
Fly
5
Nashville
— 4 nights
Fly to Flagstaff, Bus to Grand Canyon National Park
6
Grand Canyon National Park
— 4 nights
Bus to Las Vegas, Fly to Manchester

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Key Largo — 2 nights

Diving Capital of the World

Visiting Spiegel Grove and Grecian Rocks will get you outdoors. Step off the beaten path and head to North Dry Rocks and Key Largo Dry Rocks. And it doesn't end there: get outside with Conch Republic Divers, take in the architecture and atmosphere at Key Largo Baptist Church, do a tasting at Keys' Meads, and get up close and personal with brilliant marine life at Island Dolphin Care.

To find traveler tips, maps, other places to visit, and more tourist information, you can read our Key Largo trip planner.

Manchester, UK to Key Largo is an approximately 14.5-hour flight. The time zone changes from Greenwich Mean Time to Eastern Standard Time, which is usually a -5 hour difference. Traveling from Manchester in June, expect Key Largo to be much warmer, temps between 36°C and 28°C. Cap off your sightseeing on the 5th (Wed) early enough to go by car to Islamorada.
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Parks · Wildlife · Outdoors · Tours

Islamorada — 3 nights

The Village of Islands

Visiting Waterskiing & Jetskiing and Long Key State Park will get you outdoors. Step off the beaten path and head to Florida Keys Brewing Company and Islamorada Brewery & Distillery - MM82. There's much more to do: explore the gorgeous colors at Alligator Reef Light House, view the masterpieces at Michelle Nicole Lowe Art Gallery, soothe aching muscles at some of the top local wellness centers, and explore the striking landscape at Windley Key Fossil Reef Geological State Park.

To find traveler tips, ratings, where to stay, and other tourist information, read our Islamorada online itinerary planner.

Islamorada is just a stone's throw from Key Largo. Expect a daytime high around 38°C in June, and nighttime lows around 30°C. Wrap up your sightseeing on the 8th (Sat) to allow time to drive to Marathon.
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Parks · Nature · Breweries & Distilleries · Outdoors
Side Trip

Marathon — 3 nights

Heart of the Florida Keys

Step out of the city life by going to Dolphin Connection and Crane Point Museum & Nature Center. Step off the beaten path and head to Sombrero Reef and Curry Hammock State Park. And it doesn't end there: see the vivid underwater world at Coffins Patch, stroll through Sunset Park Beach, browse the fresh offerings at Paradise Produce, and look for all kinds of wild species at Marathon Garden Club.

To find maps, photos, where to stay, and other tourist information, you can read our Marathon route planner.

Drive from Islamorada to Marathon in an hour. Alternatively, you can take a bus. Expect a daytime high around 38°C in June, and nighttime lows around 30°C. Wrap up your sightseeing on the 11th (Tue) early enough to drive to Key West.
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Parks · Wildlife · Outdoors · Beaches
Side Trips

Key West — 4 nights

Conch Republic

Get some historical perspective at St. Paul's Episcopal Church and West Martello Tower. You'll explore the less-touristy side of things at Dolphin & Whale Watching and Key West Garden Club. Next up on the itinerary: see the vivid underwater world at Vandenberg Wreck, visit a coastal fixture at Key West Lighthouse and Keeper's Quarters Museum, admire the natural beauty at Audubon House & Tropical Gardens, and identify plant and animal life at Nancy Forrester's Secret Garden.

To see photos, more things to do, where to stay, and other tourist information, refer to the Key West route app.

Traveling by car from Marathon to Key West takes 1.5 hours. Alternatively, you can take a bus. Expect a daytime high around 36°C in June, and nighttime lows around 30°C. Finish your sightseeing early on the 15th (Sat) so you can fly to Nashville.
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Parks · Outdoors · Historic Sites · Wildlife

Nashville — 4 nights

Music City U.S.A.

You'll explore the less-touristy side of things at Rippa Villa and MB Roland Distillery. Visiting Crockett Park and Hermitage Golf Course will get you outdoors. Get out of town with these interesting Nashville side-trips: Clarksville (Old Glory Distilling Co. & Beachaven Vineyards & Winery) and Franklin (Leiper's Fork Distillery & Balloon Rides). Next up on the itinerary: get a new perspective on things with Boat Tours & Water Sports, brush up on your knowledge of spirits at Prichard's Distillery, take an in-depth tour of Historic Travellers Rest, and walk around Riverfront Park.

To see where to stay, other places to visit, and more tourist information, go to the Nashville visit site.

Traveling by flight from Key West to Nashville takes 6 hours. Alternatively, you can drive; or take a bus. The time zone difference when traveling from Key West to Nashville is minus 1 hour. Traveling from Key West in June, Nashville is little chillier at night with lows of 22°C. Wrap up your sightseeing on the 19th (Wed) early enough to travel to Grand Canyon National Park.
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Outdoors · Breweries & Distilleries · Parks · Historic Sites
Side Trips

Grand Canyon National Park — 4 nights

You'll explore the less-touristy side of things at Inner Canyon and Grand Canyon Mule Tours by Xanterra. Take a break from the city and head to East Rim Drive and Hermit Trail. There's much more to do: walk around Indian Garden, examine the collection at Kolb Studio, admire the striking features of Grand Canyon Railway Depot, and take some stellar pictures from Pima Point.

For where to stay, ratings, traveler tips, and more tourist information, go to the Grand Canyon National Park trip planner.

Getting from Nashville to Grand Canyon National Park by combination of flight and bus takes about 10.5 hours. Other options: do a combination of bus and shuttle. The time zone difference when traveling from Nashville to Grand Canyon National Park is minus 1 hour. Traveling from Nashville in June, you can expect nighttime temperatures to be colder in Grand Canyon National Park, with lows of 6°C. Wrap up your sightseeing on the 23rd (Sun) early enough to travel back home.
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Parks · Outdoors · Trails · Nature
Side Trip

Florida Keys travel guide

4.3
Scuba & Snorkeling · Parasailing & Paragliding · Landmarks
An archipelago of about 1,700 islands extending in a gentle arc south and southwest of Florida's mainland, the Florida Keys divide the Atlantic from the Gulf of Mexico. Many visitors on vacation come to scuba dive in the coral reefs, fossilized and exposed as sea levels declined over thousands of years. In addition to being one of the world's top diving and fishing spots, the Keys feature hundreds of shops, restaurants, bars, and various tourist attractions, most of them crowded all year long with visitors on vacation. To soak up the Keys' atmosphere and discover writer Ernest Hemingway's former haunts, drive from one island to the other all the way to Key West, located just 140 km (90 mi) from Cuba.
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