22 days in Mississippi Itinerary
Created using Inspirock Mississippi visit planner
Start: Brussels
Fly to Monroe Regional Airport, Drive to Natchez
1
Natchez
— 4 nights
Drive
2
Jackson
— 5 nights
Drive
3
Biloxi
— 5 nights
Drive
4
Hattiesburg
— 2 nights
Drive
5
Tupelo
— 3 nights
Drive
6
Tunica
— 1 night
Drive to Memphis International Airport, Fly to Brussels
End: Brussels
Fri, Sep 1 - Fri, Sep 22
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Natchez — 4 nights
Take a break from Natchez with a short trip to First Presbyterian Church of Port Gibson in Port Gibson, about 48 minutes away. Spend the 3rd (Sun) exploring nature at Melrose.
To find maps, ratings, more things to do, and more tourist information, refer to the Natchez trip planner.
Brussels, Belgium to Natchez is an approximately 17-hour combination of flight and car. The time zone difference when traveling from Brussels to Natchez is minus 7 hours. Traveling from Brussels in September, you will find days in Natchez are much hotter (36°C), and nights are somewhat warmer (23°C). Wrap up your sightseeing on the 5th (Tue) to allow time to drive to Jackson.
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To find maps, ratings, more things to do, and more tourist information, refer to the Natchez trip planner.
Brussels, Belgium to Natchez is an approximately 17-hour combination of flight and car. The time zone difference when traveling from Brussels to Natchez is minus 7 hours. Traveling from Brussels in September, you will find days in Natchez are much hotter (36°C), and nights are somewhat warmer (23°C). Wrap up your sightseeing on the 5th (Tue) to allow time to drive to Jackson.
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Highlights from your trip
Jackson — 5 nights

Venture out of the city with trips to B.B. King Museum and Delta Interpretive Center (in Indianola), Vicksburg (Old Court House Museum, U.S.S. Cairo Museum, &more) and Mississippi Delta (in Belzoni).
For photos, maps, where to stay, and more tourist information, use the Jackson trip planning app.
You can drive from Natchez to Jackson in 2 hours. Alternatively, you can do a combination of car and bus; or do a combination of car and train. Expect a daytime high around 37°C in September, and nighttime lows around 23°C. Finish your sightseeing early on the 10th (Sun) so you can drive to Biloxi.
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For photos, maps, where to stay, and more tourist information, use the Jackson trip planning app.
You can drive from Natchez to Jackson in 2 hours. Alternatively, you can do a combination of car and bus; or do a combination of car and train. Expect a daytime high around 37°C in September, and nighttime lows around 23°C. Finish your sightseeing early on the 10th (Sun) so you can drive to Biloxi.
Side Trips
Highlights from your trip
Biloxi — 5 nights

Playground of the South
Take a break from Biloxi with a short trip to Our Lady of the Gulf Catholic Church in Bay Saint Louis, about 44 minutes away. The adventure continues: head outdoors with Dailey Charters, observe the fascinating underwater world at The Institute for Marine Mammal Studies, don't miss a visit to Hurricane Katrina Memorial, and snap pictures at Biloxi Bay Bridge.
To find traveler tips, photos, ratings, and more tourist information, read our Biloxi trip planning website.
You can drive from Jackson to Biloxi in 3 hours. Alternatively, you can fly; or do a combination of train and bus. September in Biloxi sees daily highs of 36°C and lows of 26°C at night. Wrap up your sightseeing on the 15th (Fri) to allow time to drive to Hattiesburg.
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To find traveler tips, photos, ratings, and more tourist information, read our Biloxi trip planning website.
You can drive from Jackson to Biloxi in 3 hours. Alternatively, you can fly; or do a combination of train and bus. September in Biloxi sees daily highs of 36°C and lows of 26°C at night. Wrap up your sightseeing on the 15th (Fri) to allow time to drive to Hattiesburg.
Side Trips
Highlights from your trip
Hattiesburg — 2 nights

Start off your visit on the 16th (Sat): learn about wildlife with up-close encounters at Hattiesburg Zoo, then grab your bike and head to Longleaf Trace, and then immerse yourself in nature at Paul B. Johnson State Park. Get ready for a full day of sightseeing on the 17th (Sun): don't miss a visit to Hattiesburg Station, then sample the tasty concoctions at Southern Prohibition Brewing, and then look for gifts at The Lucky Rabbit.
To find ratings, photos, more things to do, and tourist information, refer to the Hattiesburg tour itinerary builder.
Traveling by car from Biloxi to Hattiesburg takes 1.5 hours. In September, daytime highs in Hattiesburg are 38°C, while nighttime lows are 23°C. Finish up your sightseeing early on the 17th (Sun) so you can go by car to Tupelo.
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To find ratings, photos, more things to do, and tourist information, refer to the Hattiesburg tour itinerary builder.
Traveling by car from Biloxi to Hattiesburg takes 1.5 hours. In September, daytime highs in Hattiesburg are 38°C, while nighttime lows are 23°C. Finish up your sightseeing early on the 17th (Sun) so you can go by car to Tupelo.
Highlights from your trip
Tupelo — 3 nights

Venture out of the city with trips to Corinth Civil War Interpretive Center (in Corinth) and Mississippi State University (in Starkville).
To find photos, maps, reviews, and more tourist information, you can read our Tupelo trip maker website.
Traveling by car from Hattiesburg to Tupelo takes 4 hours. September in Tupelo sees daily highs of 36°C and lows of 20°C at night. Finish your sightseeing early on the 20th (Wed) so you can drive to Tunica.
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To find photos, maps, reviews, and more tourist information, you can read our Tupelo trip maker website.
Traveling by car from Hattiesburg to Tupelo takes 4 hours. September in Tupelo sees daily highs of 36°C and lows of 20°C at night. Finish your sightseeing early on the 20th (Wed) so you can drive to Tunica.
Side Trips
Highlights from your trip
Tunica — 1 night

Kick off your visit on the 21st (Thu): try to win big at Gold Strike Casino, try your luck at Horseshoe Tunica, and then try your luck at Tunica Roadhouse Casino.
To find maps, reviews, ratings, and tourist information, you can read our Tunica road trip planning site.
Getting from Tupelo to Tunica by car takes about 2.5 hours. Other options: do a combination of bus and taxi. Expect a daytime high around 34°C in September, and nighttime lows around 19°C. Finish your sightseeing early on the 21st (Thu) to allow enough time to travel back home.
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To find maps, reviews, ratings, and tourist information, you can read our Tunica road trip planning site.
Getting from Tupelo to Tunica by car takes about 2.5 hours. Other options: do a combination of bus and taxi. Expect a daytime high around 34°C in September, and nighttime lows around 19°C. Finish your sightseeing early on the 21st (Thu) to allow enough time to travel back home.
Highlights from your trip
Mississippi travel guide
The Magnolia State
Still relatively unspoiled by mass tourism, Mississippi epitomizes rich history and offers warm hospitality to those who vacation here. The Mississippi River forms most of its western border, so it's no surprise that this mighty waterway shapes the lives of people calling the "Magnolia State" their home. The river influences everything from the food they eat to the music they listen to. Perhaps the easiest way to discover Mississippi is to take a drive on the 715 km (444 mi) long national parkway, which follows a route used since pre-colonial times that's famous for its scenic beauty and attractions of historical interest. At the end of the parkway sits a town packed with nearly 600 antebellum homes.