22 days in Mississippi Itinerary

22 days in Mississippi Itinerary

Created using Inspirock Mississippi trip planner

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Route & dates

22 days in Mississippi Itinerary

Start: Houston
Fly:  3​h 45​min
1
Biloxi
— 4 nights
Drive:  1​h 30​min
2
Hattiesburg
— 2 nights
Drive:  5​h 45​min
3
Oxford
— 3 nights
Drive:  1​h 15​min
4
Clarksdale
— 2 nights
Drive:  4​h
5
Jackson
— 5 nights
Drive:  2​h 30​min
6
Natchez
— 4 nights
Drive + Fly:  5​h
End: Houston

4
nights
Biloxi

A busy city on the Gulf Coast, Biloxi is one of the nation's oldest communities, first settled by Europeans in 1699.
Explore hidden gems such as Lynn Meadows Discovery Center and MGM Park. Venture out of the city with trips to Bay Saint Louis (L & N Historic Train Depot & Alice Moseley Folk Art and Antique Museum) and Friendship Oak (in Long Beach). There's lots more to do: explore the world behind art at Walter Anderson Museum of Art, contemplate in the serene atmosphere at St. Michael's Catholic Church, snap pictures at Biloxi Bay Bridge, and make a trip to Hurricane Katrina Memorial.

For photos, reviews, other places to visit, and tourist information, use the Biloxi road trip app .

Houston to Biloxi is an approximately 4-hour flight. You can also do a combination of flight and car; or drive. When traveling from Houston in July, plan for little chillier days and about the same nights in Biloxi: temperatures range from 89°F by day to 76°F at night. Cap off your sightseeing on the 10th (Wed) early enough to go by car to Hattiesburg.

Things to do in Biloxi

Museums Wildlife Tours

Side Trips

Ocean Springs, Bay Saint Louis, Gulfport, Friendship Oak
Highlights from your plan
Fishing Charters & Tours
MGM Park ©
MGM Park
Maritime and Seafood Industry Museum ©

2
nights
Hattiesburg

Hattiesburg ©
Hattiesburg is a city in the U.S. Start off your visit on the 11th (Thu): admire nature's wide array of creatures at Hattiesburg Zoo and then learn about all things military at African American Military History Museum. Keep things going the next day: immerse yourself in nature at Paul B. Johnson State Park and then learn about all things military at Mississippi Armed Forces Museum.

Start your trip to Hattiesburg by creating a personalized itinerary on Inspirock.

Traveling by car from Biloxi to Hattiesburg takes 1.5 hours. Expect a daytime high around 92°F in July, and nighttime lows around 72°F. Finish your sightseeing early on the 12th (Fri) to allow enough time to travel to Oxford.

Things to do in Hattiesburg

Parks Museums Zoos & Aquariums
Highlights from your plan
Hattiesburg Zoo ©
Hattiesburg Zoo
Paul B. Johnson State Park ©
Paul B. Johnson State Park
Mississippi Armed Forces Museum ©
Mississippi Armed Forces Museum

3
nights
Oxford

Oxford ©
Oxford is a city in, and the county seat of, Lafayette County, Mississippi, United States. Step off the beaten path and head to Rowan Oak and Square Books. Get out of town with these interesting Oxford side-trips: Room Escape Games (in Tupelo) and Grenada Lake (in Grenada). There's still lots to do: admire all the interesting features of University of Mississippi, make a trip to Historic Downtown Square, admire the masterpieces at Southside Gallery, and steep yourself in history at College Hill Presbyterian Church.

To see reviews, more things to do, photos, and tourist information, use the Oxford online trip itinerary maker .

You can drive from Hattiesburg to Oxford in 4.5 hours. Another option is to fly. When traveling from Hattiesburg in July, plan for little chillier days in Oxford, with highs around 87°F, while nights are about the same with lows around 68°F. Finish up your sightseeing early on the 16th (Tue) so you can go by car to Clarksdale.

Things to do in Oxford

Historic Sites Nature Parks

Side Trips

Room Escape Games, Grenada Lake
Highlights from your plan
Rowan Oak ©
Rowan Oak
University of Mississippi ©
University of Mississippi
Vaught-Hemingway Stadium ©
Vaught-Hemingway Stadium

2
nights
Clarksdale

Clarksdale ©
Clarksdale is a city in Coahoma County, Mississippi, and seat of the county. Start off your visit on the 17th (Wed): get engrossed in the history at The Delta Blues Museum, stop by Deak's Mississippi Saxophones & Blues Emporium, then make a trip to The Crossroad, and finally take an in-depth tour of Emmett Till museum Interpretive Center. Keep things going the next day: get engrossed in the history at Emmett Till Historic Intrepid Center, then view the masterpieces at Cat Head Delta Blues & Folk Art, then shop like a local with Stan Streets Hambone Art Gallery, and finally see the interesting displays at The Rock & Blues Museum.

For ratings, where to stay, traveler tips, and more tourist information, read Clarksdale travel planner.

You can drive from Oxford to Clarksdale in 1.5 hours. In July, daily temperatures in Clarksdale can reach 89°F, while at night they dip to 71°F. Finish your sightseeing early on the 18th (Thu) to allow enough time to travel to Jackson.

Things to do in Clarksdale

Museums Shopping

Side Trips

Emmett Till Historic Intrepid Center, Emmett Till museum Interpretive Center
Highlights from your plan
The Delta Blues Museum ©
The Delta Blues Museum
The Rock & Blues Museum ©
The Rock & Blues Museum
Cat Head Delta Blues & Folk Art ©
Cat Head Delta Blues & Folk Art

5
nights
Jackson

Jackson ©
Jackson, officially the City of Jackson, is the capital city and largest urban center of the U.S. Eschew the tourist crowds and head to Mississippi Museum of Natural Science and Jesse Brent Lower Mississippi River Museum and Interpretive Center. Venture out of the city with trips to Vicksburg (Old Court House Museum - Eva W. Davis Memorial, Texas Monument, & more). There's lots more to do: steep yourself in history at Mississippi State Capitol, revel in the low prices at Outlets of Mississippi, sample the tasty concoctions at Lucky Town Brewing Co., and stop by Lemuria Books.

For ratings, more things to do, and tourist information, read our Jackson planner .

Getting from Clarksdale to Jackson by car takes about 3 hours. In July in Jackson, expect temperatures between 91°F during the day and 73°F at night. Cap off your sightseeing on the 23rd (Tue) early enough to go by car to Natchez.

Things to do in Jackson

Museums Historic Sites Shopping

Side Trips

Vicksburg, Fannin Lanes, Outlets of Mississippi
Highlights from your plan
Mississippi Museum of Natural Science ©
Mississippi Museum of Art ©
Mississippi Museum of Art

4
nights
Natchez

Natchez ©
Natchez is the county seat and only city of Adams County, Mississippi, United States. Explore hidden gems such as Windsor Ruins and Natchez National Cemetery. The adventure continues: tour the pleasant surroundings at Bluff Park, explore the different monuments and memorials at Natchez City Cemetery, steep yourself in history at Dunleith Historic Inn, and take an in-depth tour of Natchez Museum of African American History and Culture.

To find where to stay, reviews, more things to do, and other tourist information, go to the Natchez trip itinerary builder .

You can drive from Jackson to Natchez in 2.5 hours. Alternatively, you can do a combination of bus and car; or do a combination of train and car. Expect a daytime high around 89°F in July, and nighttime lows around 71°F. Wrap up your sightseeing on the 27th (Sat) to allow time to travel back home.

Things to do in Natchez

Historic Sites Museums Scenic Drive

Side Trip

Windsor Ruins
Highlights from your plan
Natchez City Cemetery ©
Natchez City Cemetery
Choctaw Hall ©
Choctaw Hall
Natchez National Cemetery ©
Natchez National Cemetery

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