22 days in North Carolina & Coastal South Carolina Itinerary

22 days in North Carolina & Coastal South Carolina Itinerary

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Route & dates

22 days in North Carolina & Coastal South Carolina Itinerary

Start: Manchester
Fly:  13​h 15​min
1
Durham
— 2 nights
Drive:  4​h
2
Asheville
— 3 nights
Drive:  1​h 15​min
3
Bryson City
— 3 nights
Drive:  6​h 45​min
4
Hilton Head
— 3 nights
Drive:  2​h 15​min
5
Charleston
— 5 nights
Drive:  2​h 15​min
6
Myrtle Beach
— 5 nights
Fly:  10​h 45​min
End: Manchester

2
nights
Durham

Durham ©
Once the seat of a thriving tobacco industry, Durham has seen some significant moments in American history.
On the 5th (Tue), look for all kinds of wild species at Conservators Center, then get your game on at Urban Axes Durham, and then admire the natural beauty at Sarah P. Duke Gardens. Get ready for a full day of sightseeing on the next day: explore the world behind art at North Carolina Museum of Art, learn more about the world around you at North Carolina Museum of Natural Sciences, then examine the collection at The Carolina Basketball Museum, and finally contemplate in the serene atmosphere at Duke University Chapel.

For ratings, other places to visit, reviews, and tourist information, read Durham tour planner.

Manchester, UK to Durham is an approximately 13.5-hour flight. You can also do a combination of flight and train; or do a combination of flight and bus. The time zone changes from Greenwich Mean Time (GMT) to Eastern Standard Time (EST), which is usually a -5 hour difference. Traveling from Manchester in May, things will get somewhat warmer in Durham: highs are around 30°C and lows about 17°C. Wrap up your sightseeing on the 6th (Wed) to allow time to drive to Asheville.

Things to do in Durham

Museums Parks Fun & Games

Side Trips

Raleigh, The Carolina Basketball Museum, Conservators Center
Highlights from your plan
Urban Axes Durham ©
Urban Axes Durham
Sarah P. Duke Gardens ©
Sarah P. Duke Gardens
Conservators Center ©
Conservators Center

3
nights
Asheville

Asheville ©
Asheville nestles between two major mountain ranges in the scenic western section of North Carolina.
Explore Asheville's surroundings by going to Wheels Through Time Transportation Museum (in Maggie Valley), Zipline (in Lake Lure) and Pisgah Forest Gem Mine (in Pisgah Forest). Next up on the itinerary: learn about winemaking at Biltmore, let your taste buds guide you at a local gastronomic tour, cruise along Blue Ridge Pkwy, and indulge your thirst for a good beer at Sierra Nevada Brewing Co. Tours & Tastings.

To see traveler tips, maps, ratings, and other tourist information, go to the Asheville trip itinerary maker website .

Getting from Durham to Asheville by car takes about 4 hours. Other options: take a bus; or fly. Plan for a bit cooler nights when traveling from Durham in May since evenings lows in Asheville dip to 13°C. Finish your sightseeing early on the 9th (Sat) to allow enough time to drive to Bryson City.

Things to do in Asheville

Tours Outdoors Museums

Side Trips

Zipline, Sierra Nevada Brewing Co. Tours & Tastings, Blue Ridge Pkwy, Pisgah Forest Gem Mine, Wheels Through Time Transportation Museum
Highlights from your plan
Biltmore ©
Biltmore
Blue Ridge Pkwy ©
Blue Ridge Pkwy
Zipline

3
nights
Bryson City

The location of an old Cherokee village, Bryson City embraces a quiet side of the Great Smoky Mountains.
Explore Bryson City's surroundings by going to Dry Falls (in Highlands) and Max Patch (in Hot Springs). There's lots more to do: get a new perspective on things with Boat Tours & Water Sports, explore and take pictures at Cherohala Skyway, take an in-depth tour of Mountain Farm Museum, and take your sightseeing to a higher altitude at Whiteside Mountain.

For reviews, maps, other places to visit, and other tourist information, you can read our Bryson City online visit planner .

You can drive from Asheville to Bryson City in 1.5 hours. May in Bryson City sees daily highs of 28°C and lows of 11°C at night. Finish up your sightseeing early on the 12th (Tue) so you can go by car to Hilton Head.

Things to do in Bryson City

Outdoors Parks Nature

Side Trips

Cherohala Skyway, Dry Falls, Mountain Farm Museum, It's By Nature, Whiteside Mountain
Highlights from your plan
River Rafting & Tubing
Dry Falls ©
Dry Falls
Cherohala Skyway ©
Cherohala Skyway

3
nights
Hilton Head

A Hilton Head vacation may be heaven for a golfer, but the area also offers all kinds of other options for sports fans.
Step out of Hilton Head with an excursion to Pat Conroy Literary Center in Beaufort--about 1 hour away. There's lots more to do: get some thrills out on the water with a waterskiing or jet-skiing adventure, kick back and relax at Coligny Beach, get some thrills on the water with a speed boat tour, and pause for some serene contemplation at The Church of the Cross.

For reviews, ratings, maps, and tourist information, go to the Hilton Head online driving holiday planner .

You can drive from Bryson City to Hilton Head in 7 hours. Other options are to do a combination of car and flight; or do a combination of car and bus. Traveling from Bryson City in May, plan for a bit warmer nights in Hilton Head, with lows around 22°C. Cap off your sightseeing on the 15th (Fri) early enough to go by car to Charleston.

Things to do in Hilton Head

Outdoors Tours Wildlife

Side Trips

Pat Conroy Literary Center, The Church of the Cross
Highlights from your plan
Waterskiing & Jetskiing
Dolphin & Whale Watching
Speed Boats Tours

5
nights
Charleston

Many visitors describe their Charleston holiday as a warm embrace by an old, dear friend--who lived about 200 years ago.
Charleston is known for parks, historic sites, shopping, wildlife, and nightlife. Your plan includes some of its best attractions: get the lay of the land with Walking tours, admire the natural beauty at Middleton Place, go on a hair-raising tour with a ghost and vampire tour, and stroll around Joe Riley Waterfront Park.

To see other places to visit, photos, more things to do, and other tourist information, go to the Charleston trip itinerary planning tool .

Drive from Hilton Head to Charleston in 2.5 hours. Alternatively, you can take a bus. In May, daily temperatures in Charleston can reach 32°C, while at night they dip to 20°C. Wrap up your sightseeing on the 20th (Wed) to allow time to drive to Myrtle Beach.

Things to do in Charleston

Historic Sites Parks Tours

Side Trips

H. L. Hunley, Fort Moultrie
Highlights from your plan
Walking tours
Horse-Drawn Carriage Tours
Magnolia Plantation & Gardens ©
Magnolia Plantation & Gardens

5
nights
Myrtle Beach

Myrtle Beach ©
Myrtle Beach is a coastal city on the east coast of the United States in Horry County, South Carolina. Change things up with these side-trips from Myrtle Beach: Wilmington (Room Escape Games & Battleship North Carolina) and Brookgreen Gardens (in Murrells Inlet). Next up on the itinerary: observe the fascinating underwater world at Ripley's Aquarium of Myrtle Beach, experience the excitement of Myrtle Beach SkyWheel, kick back and relax at Myrtle Beach, and take a leisurely stroll along Myrtle Beach Boardwalk & Promenade.

To find ratings, traveler tips, more things to do, and other tourist information, refer to the Myrtle Beach journey builder site .

Traveling by car from Charleston to Myrtle Beach takes 2.5 hours. Alternatively, you can take a bus. May in Myrtle Beach sees daily highs of 30°C and lows of 20°C at night. Wrap up your sightseeing on the 25th (Mon) to allow time to travel back home.

Things to do in Myrtle Beach

Parks Outdoors Museums

Side Trips

North Myrtle Beach, Wilmington, Brookgreen Gardens
Highlights from your plan
Ripley's Aquarium of Myrtle Beach ©
Ripley's Aquarium of Myrtle Beach
Broadway at the Beach ©
Broadway at the Beach
Brookgreen Gardens ©
Brookgreen Gardens

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