22 days in South Carolina Itinerary

22 days in South Carolina Itinerary

Created using Inspirock South Carolina trip itinerary maker

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Route & dates

22 days in South Carolina Itinerary

Start: Chicago
Fly:  4​h 15​min
1
Charleston
— 5 nights
Drive:  3​h
2
Edisto Island
— 2 nights
Drive:  8​h
3
Saint Helena Island
— 1 day
Drive:  2​h 45​min
4
Hilton Head
— 5 nights
Drive:  1​h 15​min
5
Beaufort
— 4 nights
Drive:  3​h 45​min
6
Myrtle Beach
— 4 nights
Fly:  4​h
End: Chicago

5
nights
Charleston

Charleston ©
Many visitors describe their Charleston holiday as a warm embrace by an old, dear friend--who lived about 200 years ago.
Head to Robert Lange Studios and Six Mile Antique Mallfor some retail therapy. Do some cultural sightseeing at Aiken-Rhett House and Kahal Kadosh Beth Elohim. There's lots more to do: enjoy the sand and surf at Folly Beach Public Beach, pause for some photo ops at Fort Moultrie, steep yourself in history at Fort Sumter National Monument, and take in the local highlights with Walking tours.

To find other places to visit, photos, and tourist information, refer to the Charleston online tour planner .

Chicago to Charleston is an approximately 4.5-hour flight. You can also drive; or take a bus. You'll lose 1 hour traveling from Chicago to Charleston due to the time zone difference. Plan for much hotter temperatures traveling from Chicago in February, with highs in Charleston at 63°F and lows at 44°F. Wrap up your sightseeing on the 6th (Thu) early enough to travel to Edisto Island.

Things to do in Charleston

Museums Historic Sites Parks

Side Trips

Fort Moultrie, Folly Beach Public Beach, Six Mile Antique Mall
Highlights from your plan
The Charleston Museum ©
The Charleston Museum
Cathedral of Saint John the Baptist ©
St. Michael's Church ©
St. Michael's Church

2
nights
Edisto Island

Edisto Island
Edisto Island is one of South Carolina's Sea Islands, the larger part of which lies in Charleston County, with its southern tip in Colleton County. Start off your visit on the 7th (Fri): look for gifts at With These Hands Gallery and then enjoy the sand and surf at Edisto Beach State Park. Keep things going the next day: savor the flavors at Kings Farm Market, then examine the collection at Edisto Island Museum, and then look for all kinds of wild species at Botany Bay Plantation Heritage Preserve and Wildlife Management Area.

To find reviews, ratings, other places to visit, and tourist information, read Edisto Island planning website .

Traveling by car from Charleston to Edisto Island takes 1.5 hours. February in Edisto Island sees daily highs of 63°F and lows of 44°F at night. Finish your sightseeing early on the 8th (Sat) so you can travel to Saint Helena Island.

Things to do in Edisto Island

Parks Outdoors Nature
Highlights from your plan

1
day
Saint Helena Island

Saint Helena Island ©
Start off your visit on the 9th (Sun): take in the architecture and atmosphere at Brick Baptist Church, contemplate the long history of Penn Center, then view the masterpieces at Red Piano Too Gallery, and finally examine the collection at York W. Bailey Museum.

For more things to do, traveler tips, reviews, and more tourist information, read Saint Helena Island road trip website .

Explore your travel options from Edisto Island to Saint Helena Island with the Route module. In February in Saint Helena Island, expect temperatures between 63°F during the day and 45°F at night. Wrap up your sightseeing on the 9th (Sun) early enough to travel to Hilton Head.

Things to do in Saint Helena Island

Historic Sites Museums Shopping
Highlights from your plan
Penn Center ©
Penn Center
Brick Baptist Church ©
Brick Baptist Church
Red Piano Too Gallery ©
Red Piano Too Gallery

5
nights
Hilton Head

Hilton Head ©
A Hilton Head vacation may be heaven for a golfer, but the area also offers all kinds of other options for sports fans.
Head to Endangered Arts and Shelter Cove Towne Centrefor some retail therapy. Appreciate the collections at Coastal Discovery Museum and Art League of Hilton Head. There's still lots to do: identify plant and animal life at Sea Pines Forest Preserve, browse the different shops at Village at Wexford, see what you can catch with a fishing tour, and brush up on your knowledge of spirits at Hilton Head Distillery.

To see where to stay, photos, other places to visit, and more tourist information, read Hilton Head trip itinerary planning site .

Traveling by car from Saint Helena Island to Hilton Head takes 1.5 hours. In February, daytime highs in Hilton Head are 62°F, while nighttime lows are 46°F. Finish your sightseeing early on the 14th (Fri) to allow enough time to drive to Beaufort.

Things to do in Hilton Head

Parks Wildlife Shopping
Highlights from your plan
Sea Pines Forest Preserve ©
Sea Pines Forest Preserve
Fishing Charters & Tours
Coastal Discovery Museum ©
Coastal Discovery Museum

4
nights
Beaufort

Beaufort ©
Beaufort is a city in and the county seat of Beaufort County, South Carolina, United States. Appreciate the collections at Thibault Gallery and Atelier on Bay. Step off the beaten path and head to Old Sheldon Church Ruins and Rhett Gallery. Explore the numerous day-trip ideas around Beaufort: Morris Center for Lowcountry Heritage (in Ridgeland) and Bluffton (Pluff Mudd Art, Maye River Gallery, & more). There's still lots to do: visit a coastal fixture at Hunting Island Lighthouse, stop by McIntosh Book Shoppe, take in the architecture and atmosphere at Tabernacle Baptist Church, and stroll through Henry C. Chambers Waterfront Park.

Quickly create a custom-made itinerary for Beaufort using our trip planner.

Traveling by car from Hilton Head to Beaufort takes 1.5 hours. Alternatively, you can take a bus. In February, daytime highs in Beaufort are 63°F, while nighttime lows are 45°F. Finish your sightseeing early on the 18th (Tue) so you can drive to Myrtle Beach.

Things to do in Beaufort

Shopping Historic Sites Museums

Side Trips

Bluffton, Morris Center for Lowcountry Heritage, Old Sheldon Church Ruins
Highlights from your plan
Old Sheldon Church Ruins ©
Old Sheldon Church Ruins
Hunting Island Lighthouse ©
Hunting Island Lighthouse
The Church of the Cross ©
The Church of the Cross

4
nights
Myrtle Beach

Myrtle Beach ©
Myrtle Beach is a coastal city on the east coast of the United States in Horry County, South Carolina. Get some cultural insight at Broadway at the Beach and Duplin Winery. Appreciate the collections at Hollywood Wax Museum and Warbird Park. Explore the numerous day-trip ideas around Myrtle Beach: Litchfield Beach (in Litchfield Beach) and Cherry Grove Beach (in North Myrtle Beach). There's lots more to do: revel in the low prices at Tanger Outlets Myrtle Beach Hwy 17, do a tasting at La Belle Amie Vineyard, explore the world behind art at Franklin G. Burroughs - Simeon B. Chapin Art Museum, and take in the exciting artwork at Seacoast Artists Gallery.

To see photos, maps, reviews, and other tourist information, go to the Myrtle Beach route builder app .

You can drive from Beaufort to Myrtle Beach in 4 hours. Alternatively, you can do a combination of car and bus; or do a combination of taxi and flight. In February, plan for daily highs up to 60°F, and evening lows to 41°F. Finish your sightseeing early on the 22nd (Sat) so you can travel back home.

Things to do in Myrtle Beach

Shopping Museums Parks

Side Trips

North Myrtle Beach, Litchfield Beach, Beach Beads & Glass Studio, La Belle Amie Vineyard
Highlights from your plan
Litchfield Beach ©
Litchfield Beach
La Belle Amie Vineyard ©
La Belle Amie Vineyard
Hollywood Wax Museum ©
Hollywood Wax Museum

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