22 days in United States Itinerary

For those not from the South, Raleigh might be one of the region's better-kept travel secrets.

Kick off your visit on the 5th (Mon): head outdoors with Capital Area Greenway, then pause for some photo ops at Memorial Bell Tower, and then get your bearings at James B. Hunt Jr. Library.

For where to stay, other places to visit, reviews, and tourist information, refer to the Raleigh trip itinerary maker site.

Durham to Raleigh is an approximately half hour car ride. You can also take a train; or take a bus. In October in Raleigh, expect temperatures between 74°F during the day and 52°F at night. Wrap up your sightseeing on the 5th (Mon) to allow time to travel to Saint Louis.

Test the local claim that Saint Louis is second only to Washington, D.C.

Museum-lovers will get to explore National Blues Museum and Cardinals Hall of Fame and Museum. You'll discover tucked-away gems like Basilica of Saint Louis King Of France (The Old Cathedral ) and Central West End. There's still lots to do: admire the striking features of Frank Lloyd Wright House in Ebsworth Park, walk around Laumeier Sculpture Park, and make a trip to Jefferson National Expansion Memorial Park.

To see photos, more things to do, other places to visit, and tourist information, read Saint Louis route builder tool.

You can fly from Raleigh to Saint Louis in 4.5 hours. Other options are to drive; or take a bus. The time zone difference when traveling from Raleigh to Saint Louis is minus 1 hour. October in Saint Louis sees daily highs of 72°F and lows of 49°F at night. Finish your sightseeing early on the 8th (Thu) to allow enough time to travel to Wichita.

Mid-America All-Indian Center and Pizza Hut Museum will appeal to museum buffs. Attractions like Kansas Wildlife Exhibit and Arkansas River Trail make great kid-friendly stops.

To find where to stay, more things to do, traveler tips, and other tourist information, read our Wichita day trip planning site.

You can fly from Saint Louis to Wichita in 3.5 hours. Other options are to drive; or take a bus. October in Wichita sees daily highs of 75°F and lows of 50°F at night. Finish up your sightseeing early on the 11th (Sun) so you can travel to Denver.

Aptly nicknamed the "Mile-High City," Denver sits at an altitude of 1,600 m (5,280 ft) above sea level, located right where the Great Plains give way to the Rocky Mountains.

On the 12th (Mon), view the masterpieces at American Museum of Western Art, pause for some serene contemplation at Trinity United Methodist Church, and then walk around Confluence Park. Keep things going the next day: steep yourself in history at Center for Colorado Women's History at the Byers-Evans House, then see the interesting displays at Museo De Las Americas, and then see the interesting displays at National Ballpark Museum.

To see photos, more things to do, maps, and more tourist information, refer to the Denver route planner.

Fly from Wichita to Denver in 4 hours. Alternatively, you can drive; or do a combination of bus and train. Traveling from Wichita to Denver, you'll gain 1 hour due to the time zone difference. In October, Denver is slightly colder than Wichita - with highs of 67°F and lows of 40°F. Cap off your sightseeing on the 13th (Tue) early enough to travel to Grand Canyon National Park.

The size, shape, and color of Grand Canyon National Park combine to leave an impression on visitors as deep as the canyon itself.

Bring the kids along to Nature & Wildlife Tours and Powell Point. Discover out-of-the-way places like Hermit Road and Yavapai Point. There's much more to do: cruise along Point Imperial Drive, get curious at Yavapai Geology Museum, look for gifts at Tusayan General Store, and stroll around Indian Garden.

To see more things to do, other places to visit, traveler tips, and more tourist information, you can read our Grand Canyon National Park trip itinerary maker tool.

Traveling by combination of flight and bus from Denver to Grand Canyon National Park takes 8 hours. Alternatively, you can drive; or do a combination of bus and shuttle. Traveling from Denver in October, you can expect nighttime temperatures to be a bit cooler in Grand Canyon National Park, with lows of 31°F. Wrap up your sightseeing by early afternoon on the 17th (Sat) to allow time for travel to San Francisco.

San Francisco is a top holiday destination featuring scenic beauty and great ethnic and cultural diversity.

Kids will appreciate attractions like Fort Point and Mission Dolores. You'll explore the less-touristy side of things at Walking tours and St. Ignatius Church. And it doesn't end there: indulge in some culinary diversions at a local gastronomic tour, contemplate in the serene atmosphere at Old Cathedral of St. Mary, and take in panoramic vistas at Telegraph Hill.

Plan a trip to San Francisco easily and quickly by telling Inspirock to suggest an itinerary.

You can do a combination of bus and flight from Grand Canyon National Park to San Francisco in 8.5 hours. Other options are to drive; or do a combination of shuttle, bus, and subway. You'll gain 1 hour traveling from Grand Canyon National Park to San Francisco due to the time zone difference. When traveling from Grand Canyon National Park in October, plan for a bit warmer days in San Francisco, with highs around 73°F, while nights are warmer with lows around 56°F. Wrap up your sightseeing on the 20th (Tue) to allow time to travel to Yosemite National Park.

Massive granite mountains, towering waterfalls, groves of Giant Sequoia trees, and wilderness as far as the eye can see distinguish the landscape of Yosemite National Park.

Family-friendly places like Panorama Trail and Pothole Dome will thrill your kids. Escape the urban bustle at Cloud's Rest and Lembert Dome. It doesn't end there: tour the pleasant surroundings at May Lake Trailhead.

For photos, other places to visit, ratings, and more tourist information, use the Yosemite National Park tour builder tool.

You can drive from San Francisco to Yosemite National Park in 4 hours. When traveling from San Francisco in October, plan for little chillier days in Yosemite National Park, with highs around 66°F, while nights are much colder with lows around 28°F. On the 23rd (Fri), wrap the sightseeing up by early afternoon so you can travel to Salt Lake City.

Utah's capital and most populous city, Salt Lake City boasts a small-town feel, big-city amenities, and plenty of nature on its doorstep.

On the 24th (Sat), see the interesting displays at Land Cruiser Heritage Museum, then steep yourself in history at Beehive House, and then steep yourself in history at Assembly Hall. Get ready for a full day of sightseeing on the next day: trek along City Creek Canyon and then walk around Memory Grove Park.

For ratings, where to stay, reviews, and other tourist information, read Salt Lake City journey maker app.

Do a combination of bus and flight from Yosemite National Park to Salt Lake City in 7.5 hours. Alternatively, you can drive; or do a combination of bus and train. You'll lose 1 hour traveling from Yosemite National Park to Salt Lake City due to the time zone difference. Traveling from Yosemite National Park in October, plan for somewhat warmer nights in Salt Lake City, with lows around 46°F. On the 26th (Mon), wrap the sightseeing up by early afternoon so you can travel back home.