27 days in South Carolina Itinerary

Created using Inspirock South Carolina trip planner
Make it your trip
Drive
1
Charleston
— 7 nights
Drive
2
Columbia
— 5 nights
Drive
3
Clemson
— 7 nights
Drive
4
Sumter
— 7 nights
Drive

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Charleston — 7 nights

Many visitors describe their Charleston holiday as a warm embrace by an old, dear friend--who lived about 200 years ago.
Get some cultural insight at Fort Sumter National Monument and Brookgreen Gardens. Aiken-Rhett House and Circular Congregational Church will appeal to history buffs. Venture out of the city with trips to Litchfield Beach (in Litchfield Beach) and Harrelson's Seafood Market (in Murrells Inlet). Next up on the itinerary: steep yourself in history at Nathaniel Russell House, make a trip to Angel Oak Tree, snap pictures at Arthur Ravenel Jr. Bridge, and hit the best photo ops around with an inspiring photography tour.

To find maps, photos, other places to visit, and more tourist information, you can read our Charleston online route builder.

Myrtle Beach to Charleston is an approximately 2.5-hour car ride. You can also take a bus. In March, plan for daily highs up to 66°F, and evening lows to 47°F. Wrap up your sightseeing on the 28th (Mon) to allow time to drive to Columbia.
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Parks · Historic Sites · Nature · Museums
Side Trips

Columbia — 5 nights

Capital of Southern Hospitality

A compact capital with stately southern history, Columbia serves as a symbol of the south.
Your cultural itinerary includes sights like South Carolina State House and South Carolina State Museum. You'll explore and learn at Columbia Museum of Art and EdVenture Children's Museum. Explore Columbia's surroundings by going to Riverwalk (in Augusta), Hitchcock Woods (in Aiken) and Riverfront Antique Mall (in North Augusta). Spend the 31st (Thu) exploring nature at Congaree National Park. There's lots more to do: get to know the resident critters at Riverbanks Zoo and Garden, deepen your understanding at University of South Carolina, browse the eclectic array of goods at Soda City Market, and savor the flavors at Food & Drink.

Take the guesswork out of planning a Columbia vacation by using our trip itinerary maker.

You can drive from Charleston to Columbia in 2 hours. Alternatively, you can take a bus. Expect a daytime high around 67°F in March, and nighttime lows around 44°F. Finish up your sightseeing early on the 2nd (Sat) so you can go by car to Clemson.
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Parks · Nature · Museums · Shopping
Side Trips

Clemson — 7 nights

Clemson is a city in Pickens and Anderson counties in the U.S. state of South Carolina. Shop till you drop at Folk Pottery Museum of NE Georgia and The Bascom. Get a sense of the local culture at Hardman Farm and The Willows Pottery. You'll find plenty of places to visit near Clemson: Pisgah Forest (Cradle of Forestry & Looking Glass Falls), Pickens (Soapstone Baptist Church & Hagood Creek Petroglyph Site) and Helen (Hansel and Gretel Candy Kitchen, Anna Ruby Falls, &more). There's lots more to do: take a peaceful walk through DuPont State Recreational Forest, steep yourself in history at Stumphouse Mountain Tunnel, get engrossed in the history at Oconee History Museum, and examine the collection at Miles Through Time Automotive Museum.

To find ratings, other places to visit, and tourist information, go to the Clemson trip planner.

Traveling by car from Columbia to Clemson takes 2.5 hours. Alternatively, you can drive. In April in Clemson, expect temperatures between 74°F during the day and 54°F at night. Wrap up your sightseeing on the 9th (Sat) to allow time to drive to Sumter.
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Historic Sites · Parks · Museums · Nature
Side Trips

Sumter — 7 nights

Sumter is the county seat of Sumter County, South Carolina, United States. Deepen your sense of the past at sights like Hamlet Depot and Museum and Florence National Cemetery. For shopping fun, head to Palmetto Peddlers Antiques Mall or Pee Dee State Farmers Market. Explore Sumter's surroundings by going to Santee National Wildlife Refuge (in Summerton), Poinsett State Park (in Wedgefield) and Santee (Santee State Park, Lake Marion Golf Course, &more). The adventure continues: see the interesting displays at Airborne and Special Operations Museum, don't miss a visit to South of the Border, explore the world behind art at Sumter Gallery of Art, and admire the natural beauty at Kalmia Gardens.

For reviews, ratings, where to stay, and more tourist information, go to the Sumter trip itinerary site.

Drive from Clemson to Sumter in 3.5 hours. Alternatively, you can drive. April in Sumter sees daily highs of 76°F and lows of 52°F at night. Finish up your sightseeing early on the 16th (Sat) so you can go by car back home.
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Parks · Museums · Historic Sites · Nature
Side Trips

South Carolina travel guide

4.3
Dolphin & Whale Watching · Historic Sites · Gardens
The Palmetto State
Composed of five distinct geographic regions with boundaries roughly parallel to the Atlantic coastline, South Carolina embraces rich history, scenic beauty, and outstanding cuisine. Originally established as a slave society dependent on the cultivation of rice and indigo, the state now boasts a diverse economy that includes massive production of textile goods, chemical products, machinery, and automobiles. Widely regarded as the beginning of the Deep South, the state remains a deeply conservative part of the country, fervently clinging to its religious and cultural traditions. South Carolinians are kind and open hosts to those who vacation here, eager to share the wealth of their cultural heritage with curious visitors. With many remarkable places to visit like Charleston and Hilton Head, your itinerary here is sure to be diverse and full of scenic attractions.
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