3 days in Saint Louis & Naples Itinerary

Test the local claim that Saint Louis is second only to Washington, D.C.

Kick off your visit on the 4th (Mon): get to know the resident critters at Saint Louis Zoo and then pause for some serene contemplation at Cathedral Basilica of Saint Louis.

To see more things to do, other places to visit, ratings, and more tourist information, read our Saint Louis journey planner.

Use the Route module to find suitable travel options from your home destination to Saint Louis. In January, daytime highs in Saint Louis are 41°F, while nighttime lows are 23°F. Finish your sightseeing early on the 5th (Tue) so you can travel to Naples.

Kick off your visit on the 5th (Tue): kick back and relax at Lowdermilk Beach and then take a leisurely stroll along Naples Pier. On the 6th (Wed), you'll have a packed day of sightseeing: take in nature's colorful creations at Naples Botanical Garden, see majestic marine mammals with a dolphin and whale watching tour, and then look for gifts at Keep In Touch.

Plan trip to Naples with our itinerary maker to find out where to go and what to do.

You can fly from Saint Louis to Naples in 7.5 hours. Alternatively, you can drive; or do a combination of bus and subway. The time zone difference when traveling from Saint Louis to Naples is 1 hour. Plan for much hotter temperatures traveling from Saint Louis in January, with highs in Naples at 75°F and lows at 58°F. Wrap up your sightseeing on the 6th (Wed) to allow time to travel back home.