4 days in Cincinnati Itinerary

Situated on the north bank of the Ohio River, Cincinnati distinguished itself as the only U.S.

You've added Over-the-Rhine, Cincinnati Art Museum, American Sign Museum, and other attractions to your itinerary. Next up on the itinerary: take in the spiritual surroundings of Cathedral Basilica of the Assumption and take in the architecture and atmosphere at St. Peter in Chains Cathedral.

For maps, photos, ratings, and other tourist information, refer to the Cincinnati trip builder tool.

Saint Louis to Cincinnati is an approximately 4-hour flight. You can also drive; or take a bus. Due to the time zone difference, you'll lose 1 hour traveling from Saint Louis to Cincinnati. November in Cincinnati sees daily highs of 54°F and lows of 33°F at night. On the 29th (Sun), wrap the sightseeing up by early afternoon so you can travel back home.