4 days in Florida Keys Itinerary

4 days in Florida Keys Itinerary

Created using Inspirock Florida Keys trip itinerary planner

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Route & dates

4 days in Florida Keys Itinerary

Start: Appleton
Fly + Drive:  8​h
1
Key Largo
— 1 night
Drive:  45​min
2
Islamorada
— 1 night
Bus:  2​h
3
Key West
— 1 night
Fly:  7​h 30​min
End: Appleton

1
night
Key Largo

Key Largo ©
The northernmost island of the Florida Keys, Key Largo provides stunning scenery, a number of watersports opportunities, and plenty of areas to relax on vacation.
To see maps, reviews, where to stay, and more tourist information, read our Key Largo tour itinerary maker website .

Appleton to Key Largo is an approximately 8-hour flight. The time zone changes from Central Standard Time to Eastern Standard Time, which is usually a 1 hour difference. Expect warmer temperatures when traveling from Appleton in October; daily highs in Key Largo reach 85°F and lows reach 73°F. Cap off your sightseeing on the 24th (Wed) early enough to go by car to Islamorada.

Things to do in Key Largo

Wildlife Outdoors Tours

Side Trip

Scuba & Snorkeling
Highlights from your plan
Island Dolphin Care ©
Island Dolphin Care
Scuba & Snorkeling

1
night
Islamorada

Islamorada ©
Islamorada, long recognized as one of the world's top spots for sport fishing, encompasses six islands in the Florida Keys.
Kick off your visit on the 25th (Thu): see some colorful creatures with a scuba or snorkeling tour, then identify plant and animal life at Dolphin Research Center, and then enjoy the sand and surf at Anne's Beach.

To find reviews, photos, and more tourist information, you can read our Islamorada driving holiday planning app .

Getting from Key Largo to Islamorada by car takes about an hour. Other options: do a combination of taxi and bus. In October, plan for daily highs up to 87°F, and evening lows to 77°F. Finish your sightseeing early on the 25th (Thu) to allow enough time to drive to Key West.

Things to do in Islamorada

Wildlife Outdoors Parks

Side Trip

Dolphin Research Center
Highlights from your plan
Dolphin Research Center ©
Dolphin Research Center
Anne's Beach ©
Anne's Beach
Scuba & Snorkeling

1
night
Key West

Key West ©
Located just 140 km (90 mi) from Cuba, Key West is an island only about 6.4 km (4 mi) long and 1.6 km (1 mi) wide.
On the 26th (Fri), take an in-depth tour of Key West Shipwreck Treasure Museum, examine the collection at Mel Fisher Maritime Heritage Museum, then get curious at Florida Keys Eco-Discovery Center, and finally visit a coastal fixture at Key West Lighthouse and Keeper's Quarters Museum.

For other places to visit, reviews, more things to do, and tourist information, use the Key West online itinerary planner .

Getting from Islamorada to Key West by car takes about 2 hours. Other options: take a bus. In October, daytime highs in Key West are 86°F, while nighttime lows are 77°F. Cap off your sightseeing on the 26th (Fri) early enough to travel back home.

Things to do in Key West

Museums Historic Sites Parks
Highlights from your plan

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