4 days in Greenville Itinerary

The largest city in "upstate" South Carolina, Greenville has grown around the natural wonders of waterfalls located in the downtown area.

Change things up with these side-trips from Greenville: Columbia (Sea Lion Landing & Riverbanks Zoo and Botanical Garden), Sierra Nevada Brewing Co. Tours & Tastings (in Mills River) and Asheville (Food Tours & Spas). And it doesn't end there: brush up on your knowledge of spirits at Dark Corner Distillery, learn about wildlife with up-close encounters at Greenville Zoo, stroll around Falls Park on the Reedy, and take in the views from Liberty Bridge.

For where to stay, reviews, and more tourist information, refer to the Greenville itinerary builder website.

Expect a daytime high around 52°F in January, and nighttime lows around 34°F.