4 days in Greenville Itinerary

The largest city in "upstate" South Carolina, Greenville has grown around the natural wonders of waterfalls located in the downtown area.

Your day by day itinerary now includes Great Smoky Mountains Railroad as well as The Peace Center. Venture out of the city with trips to Biltmore (in Asheville), Hagood Mill Historic Site (in Pickens) and Anna Ruby Falls (in Helen). It doesn't end there: admire the sheer force of Falls Park on the Reedy and get to know the resident critters at Greenville Zoo.

For other places to visit, reviews, photos, and tourist information, read our Greenville route planner.

In September, daily temperatures in Greenville can reach 83°F, while at night they dip to 66°F. Wrap up your sightseeing on the 13th (Wed) early enough to travel back home.