4 days in Mississippi Itinerary

4 days in Mississippi Itinerary

Created using Inspirock Mississippi trip planner

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Route & dates

4 days in Mississippi Itinerary

Start: Louisville
Fly:  5​h 45​min
1
Biloxi
— 1 night
Drive:  4​h 15​min
2
Vicksburg
— 1 night
Drive:  4​h 45​min
3
Tupelo
— 1 night
+3
Fly + bus + foot + bus:  6​h 45​min
End: Louisville

1
night
Biloxi

Biloxi ©
A busy city on the Gulf Coast, Biloxi is one of the nation's oldest communities, first settled by Europeans in 1699.
Kick off your visit on the 5th (Wed): catch all the local highlights with T&J Island Cruises. On the next day, try your luck at Hard Rock Hotel & Casino Biloxi, then try to win big at Beau Rivage Casino, and then contemplate the long history of Beauvoir.

For where to stay, traveler tips, reviews, and other tourist information, read our Biloxi road trip planner .

Louisville to Biloxi is an approximately 6-hour flight. You can also do a combination of flight and bus; or drive. The time zone changes from Eastern Standard Time (EST) to Central Standard Time (CST), which is usually a -1 hour difference. Traveling from Louisville in September, expect Biloxi to be somewhat warmer, temps between 88°F and 72°F. Cap off your sightseeing on the 6th (Thu) early enough to go by car to Vicksburg.

Things to do in Biloxi

Casinos Fun & Games Outdoors
Highlights from your plan
Southern Coast Cruises ©
Southern Coast Cruises
Beau Rivage Casino ©
Beau Rivage Casino
Hard Rock Hotel & Casino Biloxi ©
Hard Rock Hotel & Casino Biloxi

1
night
Vicksburg

Vicksburg ©
Vicksburg is the only city and county seat of Warren County, Mississippi, United States. Kick off your visit on the 7th (Fri): get engrossed in the history at U.S.S. Cairo Museum, make a trip to Vicksburg Riverfront Murals, then make a trip to McRaven House, and finally witness the site of a historic battle at Vicksburg National Military Park.

To find maps, reviews, traveler tips, and other tourist information, read Vicksburg trip planner .

Traveling by car from Biloxi to Vicksburg takes 4.5 hours. Alternatively, you can take a bus; or do a combination of flight, taxi, and bus. Traveling from Biloxi in September, plan for slightly colder nights in Vicksburg, with lows around 67°F. Cap off your sightseeing on the 7th (Fri) early enough to go by car to Tupelo.

Things to do in Vicksburg

Parks Historic Sites Museums
Highlights from your plan
Vicksburg National Military Park ©
U.S.S. Cairo Museum ©
U.S.S. Cairo Museum
Vicksburg Riverfront Murals ©
Vicksburg Riverfront Murals

1
night
Tupelo

Tupelo ©
Tupelo is the county seat and the largest city of Lee County, Mississippi. Kick off your visit on the 8th (Sat): cruise along Natchez Trace Pkwy and then steep yourself in history at Elvis Presley Birthplace & Museum.

For other places to visit, ratings, more things to do, and other tourist information, use the Tupelo day trip website .

Traveling by car from Vicksburg to Tupelo takes 5 hours. Alternatively, you can do a combination of bus, taxi, flight, and car; or take a bus. Expect a daytime high around 87°F in September, and nighttime lows around 64°F. Finish your sightseeing early on the 8th (Sat) so you can travel back home.

Things to do in Tupelo

Outdoors Scenic Drive Museums
Highlights from your plan
Natchez Trace Pkwy ©
Natchez Trace Pkwy
Elvis Presley Birthplace & Museum ©

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