43 days in South Carolina Itinerary

43 days in South Carolina Itinerary

Created using Inspirock South Carolina itinerary builder

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Route & dates

43 days in South Carolina Itinerary

Start: Denver
Fly:  6​h 15​min
1
Charleston
— 6 nights
Drive:  2​h 15​min
2
Hilton Head
— 5 nights
Drive:  1​h
3
Beaufort
— 4 nights
Drive:  2​h 30​min
4
Aiken
— 4 nights
Drive:  1​h
5
Columbia
— 5 nights
Drive:  1​h 30​min
6
Florence
— 4 nights
Drive:  1​h 30​min
7
Myrtle Beach
— 5 nights
Drive:  3​h 30​min
8
Rock Hill
— 4 nights
Drive:  1​h 45​min
9
Greenville
— 5 nights
taxi + Fly:  5​h
End: Denver

6
nights
Charleston

Many visitors describe their Charleston holiday as a warm embrace by an old, dear friend--who lived about 200 years ago.
Go for a jaunt from Charleston to Awendaw to see The Center for Birds of Prey about 38 minutes away. Next up on the itinerary: admire the natural beauty at Magnolia Plantation & Gardens, hunt for treasures at Charleston City Market, take a memorable tour with Tours, and go on a hair-raising tour with a ghost and vampire tour.

To find other places to visit, photos, ratings, and other tourist information, use the Charleston trip app .

Denver to Charleston is an approximately 6.5-hour flight. You can also do a combination of bus and flight; or drive. The time zone difference moving from Mountain Standard Time (MST) to Eastern Standard Time (EST) is 2 hours. In January, Charleston is a bit warmer than Denver - with highs of 59°F and lows of 40°F. Finish up your sightseeing early on the 9th (Thu) so you can go by car to Hilton Head.

Things to do in Charleston

Parks Historic Sites Tours

Side Trips

H. L. Hunley, The Center for Birds of Prey
Highlights from your plan
Horse-Drawn Carriage Tours
Magnolia Plantation & Gardens ©
Magnolia Plantation & Gardens
Fort Sumter National Monument ©
Fort Sumter National Monument

5
nights
Hilton Head

A Hilton Head vacation may be heaven for a golfer, but the area also offers all kinds of other options for sports fans.
Step out of Hilton Head to go to Saint Helena Island and see York W. Bailey Museum, which is approximately 58 minutes away. There's still lots to do: hike along Hilton Head Island Bike Trails, see majestic marine mammals with a dolphin and whale watching tour, pause for some serene contemplation at St. Francis by the Sea Catholic Church, and head outdoors with Forecast Charters.

To see more things to do, reviews, ratings, and tourist information, go to the Hilton Head itinerary builder app .

You can drive from Charleston to Hilton Head in 2.5 hours. Alternatively, you can take a bus. Expect a daytime high around 58°F in January, and nighttime lows around 42°F. Finish up your sightseeing early on the 14th (Tue) so you can go by car to Beaufort.

Things to do in Hilton Head

Outdoors Parks Wildlife

Side Trips

Bluffton, York W. Bailey Museum
Highlights from your plan
Waterskiing & Jetskiing
Hilton Head Island Bike Trails ©
Hilton Head Island Bike Trails
Coligny Beach ©
Coligny Beach

4
nights
Beaufort

Beaufort ©
Beaufort is a city in and the county seat of Beaufort County, South Carolina, United States. Get out of town with these interesting Beaufort side-trips: Eden Wind Farm (in Johns Island), Lucky Duck Distillery (in Yemassee) and Palmetto Indoor Range (in Hardeeville). Next up on the itinerary: examine the collection at Pat Conroy Literary Center, stroll around Henry C. Chambers Waterfront Park, explore the ancient world of Charlesfort / Santa Elena Monument, and steep yourself in history at Old Sheldon Church Ruins.

To see reviews, more things to do, traveler tips, and tourist information, read Beaufort trip itinerary planner.

Traveling by car from Hilton Head to Beaufort takes an hour. Alternatively, you can take a bus. In January, daily temperatures in Beaufort can reach 59°F, while at night they dip to 41°F. Wrap up your sightseeing on the 18th (Sat) early enough to travel to Aiken.

Things to do in Beaufort

Historic Sites Parks Nature

Side Trips

Yemassee, Palmetto Indoor Range, Eden Wind Farm
Highlights from your plan
Old Sheldon Church Ruins ©
Old Sheldon Church Ruins
Henry C. Chambers Waterfront Park ©
Henry C. Chambers Waterfront Park
Hunting Island State Park ©
Hunting Island State Park

4
nights
Aiken

Aiken ©
Founded in 1835, the city of Aiken was named after William Aiken, the president of the South Carolina Railroad. Venture out of the city with trips to Saluda County Museum (in Saluda), Edgefield (Old Edgefield District Genealogy Society & Carolina Moon Distillery) and Blackville (God's Acre Healing Springs & Barnwell State Park). There's lots more to do: take a peaceful walk through Hitchcock Woods, don't miss a visit to Aiken Center for the Arts, take in the spiritual surroundings of St. Mary Help of Christians, and steep yourself in history at Redcliffe Plantation State.

To see photos, other places to visit, where to stay, and tourist information, read our Aiken trip itinerary planner.

Getting from Beaufort to Aiken by car takes about 2.5 hours. Expect a bit cooler evenings in Aiken when traveling from Beaufort in January, with lows around 34°F. Cap off your sightseeing on the 22nd (Wed) early enough to go by car to Columbia.

Things to do in Aiken

Parks Outdoors Historic Sites

Side Trips

Blackville, Edgefield, Redcliffe Plantation State, Mount Vintage Golf Club, Saluda County Museum
Highlights from your plan
Hitchcock Woods ©
Hitchcock Woods
God's Acre Healing Springs ©
God's Acre Healing Springs
St. Mary Help of Christians ©
St. Mary Help of Christians

5
nights
Columbia

Columbia ©
A compact capital with stately southern history, Columbia serves as a symbol of the south.
Change things up with these side-trips from Columbia: Old Courthouse (in Newberry), Crooked Creek Park (in Chapin) and North Augusta (North Augusta Greenway Trail & Brick Pond Park). Next up on the itinerary: have some family-friendly fun at The Final Door Escape Room Columbia, identify plant and animal life at Congaree Creek Heritage Preserve, hike along Cayce Riverwalk, and get a sense of history and politics at South Carolina State House.

To see traveler tips, more things to do, ratings, and more tourist information, refer to the Columbia route website .

Getting from Aiken to Columbia by car takes about an hour. In January, plan for daily highs up to 57°F, and evening lows to 37°F. Wrap up your sightseeing on the 27th (Mon) early enough to travel to Florence.

Things to do in Columbia

Parks Historic Sites Outdoors

Side Trips

Cayce, North Augusta, Crooked Creek Park, Old Courthouse
Highlights from your plan
The Final Door Escape Room Columbia ©
Riverbanks Zoo and Botanical Garden ©
Elmwood Cemetery ©
Elmwood Cemetery

4
nights
Florence

Florence ©
Florence is a city in Florence County, South Carolina, United States, and it is probably best known for the intersection of I-95 and I-20, and the eastern terminus of I-20. Change things up with these side-trips from Florence: Fryar's Topiary Garden (in Bishopville), Manning (Wyboo Golf Club & Swamp Fox Murals Trail) and Moore Farms Botanical Garden (in Lake City). And it doesn't end there: walk around Williamson Park, take in the architecture and atmosphere at Florence Baptist Temple, stroll through Florence Veterans Park, and play a few rounds at Cheraw State Park Golf Course.

To find ratings, other places to visit, maps, and tourist information, read Florence online vacation planner .

Traveling by car from Columbia to Florence takes 1.5 hours. In January, daily temperatures in Florence can reach 56°F, while at night they dip to 35°F. Finish your sightseeing early on the 31st (Fri) to allow enough time to drive to Myrtle Beach.

Things to do in Florence

Parks Outdoors Golf

Side Trips

Manning, Cheraw State Park Golf Course, Lynches River County Park, Fryar's Topiary Garden, Williamson Park
Highlights from your plan
Fryar's Topiary Garden ©
Fryar's Topiary Garden
Lynches River County Park ©
Lynches River County Park
Moore Farms Botanical Garden ©
Moore Farms Botanical Garden

5
nights
Myrtle Beach

Myrtle Beach ©
Myrtle Beach is a coastal city on the east coast of the United States in Horry County, South Carolina. Get out of town with these interesting Myrtle Beach side-trips: Murrells Inlet (Brookgreen Gardens & Huntington Beach State Park), Bookends Used Bookstore (in North Myrtle Beach) and SC-CARES - SC Coastal Animal Rescue & Educational Sanctuary (in Georgetown). And it doesn't end there: get up close and personal with brilliant marine life at Ripley's Aquarium of Myrtle Beach, take a stroll through Broadway at the Beach, see the interesting displays at Myrtle Beach Pinball Museum, and admire the majestic nature at Myrtle Beach State Park.

For reviews, photos, maps, and other tourist information, go to the Myrtle Beach trip planner .

Traveling by car from Florence to Myrtle Beach takes 1.5 hours. In January, daytime highs in Myrtle Beach are 56°F, while nighttime lows are 38°F. Cap off your sightseeing on the 5th (Wed) early enough to travel to Rock Hill.

Things to do in Myrtle Beach

Parks Outdoors Museums

Side Trips

Murrells Inlet, North Myrtle Beach, SC-CARES - SC Coastal Animal Rescue & Educational Sanctuary
Highlights from your plan
Broadway at the Beach ©
Broadway at the Beach
Ripley's Aquarium of Myrtle Beach ©
Ripley's Aquarium of Myrtle Beach
Brookgreen Gardens ©
Brookgreen Gardens

4
nights
Rock Hill

Rock Hill ©
Rock Hill is the largest city in York County, South Carolina, United States and the fifth-largest city in the state. Explore the numerous day-trip ideas around Rock Hill: Bob Doster's Backstreet Studio (in Lancaster), Cherokee Speedway (in Gaffney) and Chester State Park (in Chester). There's much more to do: test your problem-solving skills at popular escape rooms, grab your bike and head to Giordana Velodrome, try for a hole-in-one at Mr Putty's Fun Park, and walk around Walter Y. Elisha Park.

For maps, traveler tips, where to stay, and tourist information, read our Rock Hill online route maker .

Traveling by car from Myrtle Beach to Rock Hill takes 3.5 hours. Traveling from Myrtle Beach in February, expect a bit cooler with lows of 36°F in Rock Hill. Finish up your sightseeing early on the 9th (Sun) so you can travel to Greenville.

Things to do in Rock Hill

Parks Outdoors Trails

Side Trips

Mr Putty's Fun Park, Chester State Park, Walter Y. Elisha Park, Bob Doster's Backstreet Studio, Cherokee Speedway
Highlights from your plan
Chester State Park ©
Chester State Park
Room Escape Games
Bob Doster's Backstreet Studio ©
Bob Doster's Backstreet Studio

5
nights
Greenville

Greenville ©
The largest city in "upstate" South Carolina, Greenville has grown around the natural wonders of waterfalls located in the downtown area.
Get out of town with these interesting Greenville side-trips: Pretty Place (Symmes Chapel) (in Cleveland), Jones Gap State Park (in Marietta) and Yellow Branch Falls (in Mountain Rest). And it doesn't end there: admire the sheer force of Falls Park on the Reedy, examine the collection at Hagood Creek Petroglyph Site of SC, head outdoors with Mice on Main, and get your game on at Craft Axe Throwing- Greenville.

To see photos, reviews, traveler tips, and more tourist information, read Greenville day trip planning site .

Traveling by car from Rock Hill to Greenville takes 2 hours. In February, daytime highs in Greenville are 57°F, while nighttime lows are 38°F. Cap off your sightseeing on the 14th (Fri) early enough to travel back home.

Things to do in Greenville

Parks Nature Wildlife

Side Trips

Twin Falls/Eastatoe Falls, Hagood Creek Petroglyph Site of SC, Twin Lakes Park, Pretty Place (Symmes Chapel), Southern Hills Lavender
Highlights from your plan
Falls Park on the Reedy ©
Falls Park on the Reedy
Room Escape Games
Craft Axe Throwing- Greenville ©
Craft Axe Throwing- Greenville

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