5 days in Buffalo & San Francisco Itinerary

The most populous city in the state after New York, Buffalo serves as the gateway to Niagara Falls and Canada for many travelers.

On the 26th (Wed), Head underground at Cave of the Winds, then step off the mainland to explore Three Sisters Island, then take in the dramatic scenery at Niagara Falls, and finally admire the sheer force of Bridal Veil Falls. Get ready for a full day of sightseeing on the 27th (Thu): immerse yourself in nature at Whirlpool State Park, enjoy breathtaking views from Niagara Falls Observation Tower, and then explore the different monuments and memorials at Forest Lawn.

To find other places to visit, ratings, photos, and tourist information, read our Buffalo trip planner.

Tampa to Buffalo is an approximately 5.5-hour flight. You can also drive; or do a combination of train and taxi. Traveling from Tampa in May, expect Buffalo to be cooler, temps between 69°F and 50°F. Finish up your sightseeing early on the 27th (Thu) so you can travel to San Francisco.

San Francisco is a top holiday destination featuring scenic beauty and great ethnic and cultural diversity.

On the 28th (Fri), head off the coast to Alcatraz Island, take in the waterfront at Fisherman's Wharf, and then snap pictures at Golden Gate Bridge. Get ready for a full day of sightseeing on the next day: browse the different shops at Ferry Building Marketplace, admire the masterpieces at Asian Art Museum, and then walk around Golden Gate Park.

To see reviews, maps, more things to do, and tourist information, go to the San Francisco trip builder tool.

Getting from Buffalo to San Francisco by flight takes about 9 hours. Other options: drive; or do a combination of train and subway. The time zone difference moving from Eastern Standard Time to Pacific Standard Time is minus 3 hours. In May, daily temperatures in San Francisco can reach 69°F, while at night they dip to 53°F. On the 30th (Sun), wrap the sightseeing up by early afternoon so you can travel back home.