6 days in Florida Keys Itinerary

6 days in Florida Keys Itinerary

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Route & dates

6 days in Florida Keys Itinerary

Start: Saint Louis
Fly:  6​h 30​min
1
Key West
— 1 night
bus:  1​h 15​min
2
Marathon
— 2 nights
Drive:  1​h 15​min
3
Key Largo
— 2 nights
shuttle + Fly:  6​h 30​min
End: Saint Louis

1
night
Key West

Key West ©
Located just 140 km (90 mi) from Cuba, Key West is an island only about 6.4 km (4 mi) long and 1.6 km (1 mi) wide.
On the 3rd (Wed), explore and take pictures at The Overseas Highway, then contemplate the long history of Truman Little White House, and then admire the majestic nature at Fort Zachary Taylor.

To find traveler tips, photos, other places to visit, and other tourist information, read Key West road trip site .

Saint Louis to Key West is an approximately 6.5-hour flight. You can also do a combination of flight and shuttle; or drive. The time zone difference moving from Central Standard Time to Eastern Standard Time is 1 hour. Expect a bit warmer evenings in Key West when traveling from Saint Louis in July, with lows around 81°F. Finish up your sightseeing early on the 3rd (Wed) so you can catcht the bus to Marathon.

Things to do in Key West

Outdoors Historic Sites Beaches
Highlights from your plan
Fort Zachary Taylor ©
Fort Zachary Taylor
The Overseas Highway ©
The Overseas Highway
Truman Little White House ©
Truman Little White House

2
nights
Marathon

Marathon ©
A tiny city just 16 km (10 mi) long, Marathon is spread across several islands in the middle of the Florida Keys.
On the 4th (Thu), kick back and relax at Sombrero Beach, identify plant and animal life at The Turtle Hospital, and then kick back and relax at Bahia Honda State Park. Keep things going the next day: cast your line with a fishing tour, then identify plant and animal life at Dolphin Research Center, and then take in the views from Seven Mile Bridge.

To find photos, traveler tips, and other tourist information, use the Marathon planner .

Traveling by bus from Key West to Marathon takes 1.5 hours. Alternatively, you can drive. In July, daily temperatures in Marathon can reach 92°F, while at night they dip to 81°F. Wrap up your sightseeing on the 5th (Fri) to allow time to drive to Key Largo.

Things to do in Marathon

Parks Outdoors Wildlife

Side Trip

Bahia Honda State Park
Highlights from your plan
Dolphin Research Center ©
Dolphin Research Center
The Turtle Hospital ©
The Turtle Hospital
Fishing Charters & Tours

2
nights
Key Largo

Key Largo ©
The northernmost island of the Florida Keys, Key Largo provides stunning scenery, a number of watersports opportunities, and plenty of areas to relax on vacation.
Start off your visit on the 6th (Sat): identify plant and animal life at Anhinga Trail and then immerse yourself in nature at John Pennekamp Coral Reef State Park. Here are some ideas for day two: fly like a bird with a parasailing or paragliding tour, then get interesting insight from Tours, and then look for all kinds of wild species at Florida Keys Wild Bird Rehabilitation Center.

For traveler tips, photos, more things to do, and other tourist information, read Key Largo visit planner .

You can drive from Marathon to Key Largo in 1.5 hours. Another option is to take a bus. Traveling from Marathon in July, Key Largo is little chillier at night with lows of 76°F. Wrap up your sightseeing on the 7th (Sun) early enough to travel back home.

Things to do in Key Largo

Outdoors Wildlife Parks

Side Trips

Fishing Charters & Tours, Anhinga Trail
Highlights from your plan
Anhinga Trail ©
Anhinga Trail
Parasailing & Paragliding

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