6 days in Philadelphia & Durham Itinerary

Steeped in cultural and historical heritage, Philadelphia is known as the birthplace of U.S.

Get out of town with these interesting Philadelphia side-trips: Winterthur Museum, Garden & Library (in Winterthur) and Longwood Gardens (in Kennett Square). The adventure continues: ponder the world of politics at Independence Hall, try your luck at Harrah's Philadelphia, see the interesting displays at The Franklin Institute, and take an in-depth tour of Eastern State Penitentiary.

For more things to do, where to stay, ratings, and tourist information, read our Philadelphia road trip planning app.

Use the Route module to find travel options from your starting location to Philadelphia. Expect a daytime high around 57°F in November, and nighttime lows around 40°F. Finish your sightseeing early on the 13th (Fri) to allow enough time to travel to Durham.

Once the seat of a thriving tobacco industry, Durham has seen some significant moments in American history.

On the 14th (Sat), examine the collection at The Carolina Basketball Museum, then identify plant and animal life at Conservators Center, and then admire the natural beauty at Sarah P. Duke Gardens. Get ready for a full day of sightseeing on the 15th (Sun): hike along Neuse River Trail, get a new perspective on nature at North Carolina Museum of Natural Sciences, and then deepen your understanding at Duke University.

To see where to stay, more things to do, reviews, and more tourist information, refer to the Durham travel planner.

Fly from Philadelphia to Durham in 5 hours. Alternatively, you can drive; or take a bus. In November, daytime highs in Durham are 62°F, while nighttime lows are 39°F. Wrap up your sightseeing on the 15th (Sun) to allow time to travel back home.