6 days in South Carolina Itinerary

6 days in South Carolina Itinerary

Created using Inspirock South Carolina tour itinerary builder

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Route & dates

6 days in South Carolina Itinerary

Start: Columbus
Fly:  2​h
1
Myrtle Beach
— 1 day
Drive:  2​h
2
Mount Pleasant
— 2 nights
Drive:  2​h 30​min
3
Hilton Head
— 2 nights
Drive:  4​h 45​min
4
Greenville
— 1 night
taxi + Fly:  5​h
End: Columbus

1
day
Myrtle Beach

Myrtle Beach ©
Myrtle Beach is a coastal city on the east coast of the United States in Horry County, South Carolina. On the 14th (Sat), admire the masterpieces at Brookgreen Gardens and then enjoy some diversion at 707 Indoor Shooting Range.

For maps and tourist information, refer to the Myrtle Beach trip planner.

Columbus to Myrtle Beach is an approximately 2-hour flight. You can also drive; or take a bus. Traveling from Columbus in September, Myrtle Beach is somewhat warmer at night with lows of 69°F. Wrap up your sightseeing on the 14th (Sat) to allow time to drive to Mount Pleasant.

Things to do in Myrtle Beach

Parks Museums Fun & Games

Side Trip

Brookgreen Gardens
Highlights from your plan
Brookgreen Gardens ©
Brookgreen Gardens
707 Indoor Shooting Range ©
707 Indoor Shooting Range

2
nights
Mount Pleasant

Mount Pleasant is a large suburban town in Charleston County, South Carolina, United States. On the 15th (Sun), take a tour by water with Boat Tours & Water Sports, then get the lay of the land with Walking tours, and then don't miss a visit to H. L. Hunley. Here are some ideas for day two: deepen your knowledge of military history at Fort Sumter National Monument, then test your problem-solving skills at popular escape rooms, and then see majestic marine mammals with a dolphin and whale watching tour.

To see more things to do, other places to visit, where to stay, and more tourist information, go to the Mount Pleasant trip itinerary maker app .

Traveling by car from Myrtle Beach to Mount Pleasant takes 2 hours. Alternatively, you can take a bus. Expect a daytime high around 84°F in September, and nighttime lows around 69°F. Finish your sightseeing early on the 16th (Mon) to allow enough time to drive to Hilton Head.

Things to do in Mount Pleasant

Tours Outdoors Wildlife

Side Trips

Charleston, H. L. Hunley, Dolphin & Whale Watching
Highlights from your plan
Walking tours
Fort Sumter National Monument ©
Fort Sumter National Monument
Fishing Charters & Tours

2
nights
Hilton Head

A Hilton Head vacation may be heaven for a golfer, but the area also offers all kinds of other options for sports fans.
On the 17th (Tue), pause for some serene contemplation at St. Francis by the Sea Catholic Church, race across the water with a speed boat tour, and then get some thrills out on the water with a waterskiing or jet-skiing adventure. On the 18th (Wed), you'll have a packed day of sightseeing: see what you can catch with a fishing tour, then sample the fine beverages at Hilton Head Distillery, and then trek along Hilton Head Island Bike Trails.

To see reviews, more things to do, maps, and more tourist information, go to the Hilton Head trip itinerary builder tool .

Drive from Mount Pleasant to Hilton Head in 2.5 hours. Alternatively, you can take a bus. In September, daytime highs in Hilton Head are 84°F, while nighttime lows are 71°F. Wrap up your sightseeing on the 18th (Wed) to allow time to drive to Greenville.

Things to do in Hilton Head

Outdoors Tours Wildlife
Highlights from your plan
Waterskiing & Jetskiing
Hilton Head Island Bike Trails ©
Hilton Head Island Bike Trails
Speed Boats Tours

1
night
Greenville

Greenville ©
The largest city in "upstate" South Carolina, Greenville has grown around the natural wonders of waterfalls located in the downtown area.
On the 19th (Thu), take in the dramatic scenery at Falls Park on the Reedy, take in the views from Liberty Bridge, sample the fine beverages at Dark Corner Distillery, then test your problem-solving skills at popular escape rooms, and finally experience rural life at Southern Hills Lavender.

For where to stay, other places to visit, and more tourist information, read our Greenville trip planner .

Getting from Hilton Head to Greenville by car takes about 5 hours. Other options: do a combination of flight and taxi; or do a combination of bus, flight, and taxi. Traveling from Hilton Head in September, Greenville is a bit cooler at night with lows of 66°F. Wrap up your sightseeing on the 19th (Thu) to allow time to travel back home.

Things to do in Greenville

Nature Parks Fun & Games

Side Trip

Southern Hills Lavender
Highlights from your plan
Falls Park on the Reedy ©
Falls Park on the Reedy
Dark Corner Distillery ©
Dark Corner Distillery
Room Escape Games

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