6 days in Southeast Missouri Itinerary

Start off your visit on the 14th (Wed): get a taste of the local shopping with Astral Glass Studio and Gallery, then sample the fine beverages at Pinckney Bend Distillery, then get to know the fascinating history of John Colter Memorial, and finally learn about winemaking at Robller Vineyard.

To see maps, photos, traveler tips, and tourist information, read our New Haven tour planning website.

New York City to New Haven is an approximately 16-hour car ride. Due to the time zone difference, you'll gain 1 hour traveling from New York City to New Haven. Plan for slightly colder nights when traveling from New York City in September since evenings lows in New Haven dip to 58°F. Wrap up your sightseeing on the 14th (Wed) to allow time to drive to Sainte Genevieve.

Kick off your visit on the 15th (Thu): take an in-depth tour of Bolduc House Museum, then contemplate the long history of Felix Valle House State Historic Site, and then pause for some serene contemplation at Sainte Genevieve Catholic Parish. Get ready for a full day of sightseeing on the 16th (Fri): do a tasting at Watertower Winery, learn about winemaking at Crown Valley Winery, and then learn about winemaking at Cave Vineyard.

To find reviews, other places to visit, photos, and more tourist information, read our Sainte Genevieve road trip planning tool.

Getting from New Haven to Sainte Genevieve by car takes about 2 hours. September in Sainte Genevieve sees daily highs of 81°F and lows of 59°F at night. Wrap up your sightseeing on the 16th (Fri) to allow time to drive to New Madrid.

On the 17th (Sat), view the masterpieces at New Madrid Historical Museum, get engrossed in the history at Higgerson School Historic Site, and then steep yourself in history at Hunter-Dawson State Historic Site.

For reviews, photos, traveler tips, and tourist information, read our New Madrid holiday planner.

You can drive from Sainte Genevieve to New Madrid in 2 hours. In September, plan for daily highs up to 82°F, and evening lows to 59°F. Finish your sightseeing early on the 18th (Sun) to allow enough time to drive back home.