7 days in Mississippi Itinerary

7 days in Mississippi Itinerary

Created using Inspirock Mississippi itinerary planner

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Route & dates

7 days in Mississippi Itinerary

Start: Kalamazoo
Fly + Drive:  7​h 15​min
1
Tupelo
— Few hours
Drive:  6​h
2
Biloxi
— 1 night
Drive:  4​h 15​min
3
Natchez
— 1 night
Drive:  1​h 45​min
4
Vicksburg
— 2 nights
Drive:  2​h 45​min
5
Clarksdale
— 1 night
Drive + Fly:  6​h 45​min
End: Kalamazoo

few
hours
Tupelo

Tupelo ©
Tupelo is the county seat and the largest city of Lee County, Mississippi. To see reviews, traveler tips, ratings, and more tourist information, you can read our Tupelo trip itinerary planning tool .

Kalamazoo to Tupelo is an approximately 7.5-hour flight. You can also drive. The time zone difference when traveling from Kalamazoo to Tupelo is minus 1 hour. Traveling from Kalamazoo in March, expect nights in Tupelo to be a bit warmer, around 42°F, while days are warmer, around 64°F. Finish your sightseeing early on the 30th (Sat) to allow enough time to drive to Biloxi.

Things to do in Tupelo

Museums
Highlights from your plan
Tupelo Veteran's Museum ©
Tupelo Veteran's Museum

1
night
Biloxi

Biloxi ©
A busy city on the Gulf Coast, Biloxi is one of the nation's oldest communities, first settled by Europeans in 1699.
Kick off your visit on the 31st (Sun): try to win big at Beau Rivage Casino, explore the engaging exhibits at Lynn Meadows Discovery Center, and then kick back and relax at Biloxi Beach. Keep things going the next day: contemplate in the serene atmosphere at St. Michael's Catholic Church, explore the world behind art at Walter Anderson Museum of Art, then examine the collection at Maritime and Seafood Industry Museum, and finally try your luck at Hard Rock Hotel & Casino Biloxi.

For photos, traveler tips, where to stay, and other tourist information, read Biloxi trip itinerary maker tool .

Getting from Tupelo to Biloxi by car takes about 6 hours. Other options: do a combination of car and flight; or do a combination of bus and flight. Plan for a bit warmer nights when traveling from Tupelo in March since evenings lows in Biloxi dip to 54°F. Wrap up your sightseeing on the 1st (Mon) to allow time to drive to Natchez.

Things to do in Biloxi

Casinos Fun & Games Museums

Side Trips

Walter Anderson Museum of Art, Lynn Meadows Discovery Center
Highlights from your plan
Beau Rivage Casino ©
Beau Rivage Casino
Walter Anderson Museum of Art ©
Walter Anderson Museum of Art
Maritime and Seafood Industry Museum ©

1
night
Natchez

Natchez ©
Natchez is the county seat and only city of Adams County, Mississippi, United States. On the 2nd (Tue), get engrossed in the history at Natchez Museum of African American History and Culture, contemplate the long history of First Presbyterian Church, contemplate the long history of Longwood, then do a tasting at Old South Winery, and finally explore the different monuments and memorials at Natchez National Cemetery.

To see traveler tips, photos, where to stay, and more tourist information, go to the Natchez trip planner .

Traveling by car from Biloxi to Natchez takes 4.5 hours. Alternatively, you can do a combination of bus, train, and car; or do a combination of bus and car. Traveling from Biloxi in April, expect a bit cooler with lows of 55°F in Natchez. Wrap up your sightseeing on the 2nd (Tue) to allow time to drive to Vicksburg.

Things to do in Natchez

Historic Sites Museums Wineries
Highlights from your plan
Longwood ©
Longwood
Natchez National Cemetery ©
Natchez National Cemetery
First Presbyterian Church ©
First Presbyterian Church

2
nights
Vicksburg

Vicksburg ©
Vicksburg is the only city and county seat of Warren County, Mississippi, United States. Kick off your visit on the 3rd (Wed): take an in-depth tour of Old Court House Museum - Eva W. Davis Memorial, see the interesting displays at Jesse Brent Lower Mississippi River Museum and Interpretive Center, then contemplate the long history of Grand Gulf Military Park, and finally steep yourself in history at Windsor Ruins. On the next day, take an in-depth tour of U.S.S. Cairo Museum, see the interesting displays at The Old Depot Museum, then take in the history at Vicksburg National Military Park, and finally make a trip to Anchuca Mansion.

To find other places to visit, photos, more things to do, and more tourist information, you can read our Vicksburg trip planner .

You can drive from Natchez to Vicksburg in 2 hours. In April in Vicksburg, expect temperatures between 77°F during the day and 56°F at night. Wrap up your sightseeing on the 4th (Thu) to allow time to travel to Clarksdale.

Things to do in Vicksburg

Historic Sites Museums Parks

Side Trip

Port Gibson
Highlights from your plan
Windsor Ruins ©
Windsor Ruins
U.S.S. Cairo Museum ©
U.S.S. Cairo Museum

1
night
Clarksdale

Clarksdale ©
Clarksdale is a city in Coahoma County, Mississippi, and seat of the county. Start off your visit on the 5th (Fri): take in the exciting artwork at Stan Streets Hambone Art Gallery, examine the collection at The Rock & Blues Museum, then view the masterpieces at Cat Head Delta Blues & Folk Art, and finally get engrossed in the history at The Delta Blues Museum.

Ask Inspirock to suggest an itinerary and make planning a trip to Clarksdale fast, fun, and easy.

Traveling by car from Vicksburg to Clarksdale takes 3 hours. Traveling from Vicksburg in April, you will find days in Clarksdale are little chillier (72°F), and nights are about the same (53°F). Wrap up your sightseeing on the 5th (Fri) early enough to travel back home.

Things to do in Clarksdale

Museums Shopping
Highlights from your plan
Cat Head Delta Blues & Folk Art ©
Cat Head Delta Blues & Folk Art
The Delta Blues Museum ©
The Delta Blues Museum
The Rock & Blues Museum ©
The Rock & Blues Museum

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