8 days in Jefferson City & Key West Itinerary

Jefferson City is the capital of the State of Missouri and the fifteenth most populous city in the state. Explore Jefferson City's surroundings by going to Columbia (Lions-Stephens Park, Columbia Culinary Tours, &more), Ozark Distillery and Brewery (in Osage Beach) and Swinging Bridge (in Brumley). There's lots more to do: take an in-depth tour of The National Churchill Museum, steep yourself in history at Missouri State Penitentiary, appreciate the history behind Lewis and Clark Monument Trailhead Plaza, and test your team's savvy at Mississippi Mind Trap.

For photos, reviews, more things to do, and other tourist information, use the Jefferson City tour app.

Saint Louis to Jefferson City is an approximately 2.5-hour car ride. October in Jefferson City sees daily highs of 71°F and lows of 49°F at night. On the 5th (Mon), wrap the sightseeing up by early afternoon so you can travel to Key West.

Located just 140 km (90 mi) from Cuba, Key West is an island only about 6.4 km (4 mi) long and 1.6 km (1 mi) wide.

Key West is known for wildlife, adventure, and museums. Your plan includes some of its best attractions: see the interesting displays at The Ernest Hemingway Home and Museum, identify plant and animal life at Key West Butterfly & Nature Conservatory, see some colorful creatures with a scuba or snorkeling tour, and make a trip to Southernmost Point.

For traveler tips, photos, and tourist information, read our Key West attractions planner.

Use the Route module to find suitable travel options from Jefferson City to Key West. The time zone difference when traveling from Jefferson City to Key West is 1 hour. When traveling from Jefferson City in October, plan for somewhat warmer days and much warmer nights in Key West: temperatures range from 86°F by day to 77°F at night. Cap off your sightseeing on the 9th (Fri) early enough to travel back home.