8 days in Midwest Itinerary

8 days in Midwest Itinerary

Created using Inspirock Midwest travel planner

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Route & dates

8 days in Midwest Itinerary

Start: Minneapolis
Fly:  4​h
1
Des Moines
— Few hours
Fly:  3​h 45​min
2
Saint Louis
— 2 nights
Fly + Drive:  3​h 45​min
3
Branson
— 2 nights
Fly:  4​h 15​min
4
Chicago
— 3 nights
Fly:  3​h 30​min
End: Minneapolis

few
hours
Des Moines

Des Moines
Des Moines is the capital and the most populous city in the U.S. Kick off your visit on the 20th (Sat): grab your bike and head to High Trestle Trail.

To find where to stay, reviews, other places to visit, and tourist information, read our Des Moines sightseeing planner .

Minneapolis to Des Moines is an approximately 4-hour flight. You can also drive; or take a bus. When traveling from Minneapolis in April, plan for a bit warmer days in Des Moines, with highs around 62°F, while nights are about the same with lows around 41°F. Cap off your sightseeing on the 20th (Sat) early enough to travel to Saint Louis.

Things to do in Des Moines

Trails Outdoors Parks

Side Trip

High Trestle Trail

2
nights
Saint Louis

Saint Louis ©
Test the local claim that Saint Louis is second only to Washington, D.C.
Start off your visit on the 21st (Sun): admire nature's wide array of creatures at Saint Louis Zoo, then take in nature's colorful creations at Missouri Botanical Garden, and then have some family-friendly fun at Top Notch Axe Throwing St. Louis. On the next day, look for all kinds of wild species at Sachs Butterfly House, then get to know the fascinating history of St. Charles Historic District, then see the interesting displays at City Museum, and finally pause for some serene contemplation at Cathedral Basilica of Saint Louis.

Before you visit Saint Louis, use our trip planner to discover what you can do and see there.

You can fly from Des Moines to Saint Louis in 4 hours. Other options are to drive; or take a bus. In April, plan for daily highs up to 67°F, and evening lows to 46°F. Finish up your sightseeing early on the 22nd (Mon) so you can travel to Branson.

Things to do in Saint Louis

Parks Zoos & Aquariums Historic Sites

Side Trips

St. Charles Historic District, Sachs Butterfly House
Highlights from your plan
Cathedral Basilica of Saint Louis ©
Cathedral Basilica of Saint Louis
City Museum ©
City Museum
Saint Louis Zoo ©
Saint Louis Zoo

2
nights
Branson

Branson ©
Nestled in Missouri's beautiful Ozark Mountains lies one of the country's most attractive vacation towns for year-round family entertainment.
On the 23rd (Tue), look for all kinds of wild species at Shepherd of the Hills Fish Hatchery, contemplate the waterfront views at Table Rock Lake, and then have some family-friendly fun at Escape Code. On the 24th (Wed), you'll have a packed day of sightseeing: identify plant and animal life at National Tiger Sanctuary and then get a new perspective on things with Boat Tours & Water Sports.

For photos, ratings, maps, and more tourist information, read Branson travel tool .

Getting from Saint Louis to Branson by combination of flight and car takes about 4 hours. Other options: drive; or take a bus. Expect a daytime high around 67°F in April, and nighttime lows around 47°F. Wrap up your sightseeing on the 24th (Wed) early enough to travel to Chicago.

Things to do in Branson

Wildlife Parks Outdoors

Side Trips

Table Rock Lake, National Tiger Sanctuary
Highlights from your plan
Escape Code ©
Escape Code
National Tiger Sanctuary ©
National Tiger Sanctuary
Table Rock Lake ©
Table Rock Lake

3
nights
Chicago

Chicago ©
A huge and vibrant city, Chicago is home to top-notch theaters, shops, museums, galleries, and restaurants.
Your inner history buff will appreciate Millennium Park and Fourth Presbyterian Church. Let the collections at Museum of Science and Industry and Ernest Hemingway Birthplace capture your imagination. The adventure continues: explore the world behind art at The Art Institute of Chicago, explore and take pictures at Wrigley Field, pause for some photo ops at Cloud Gate, and meet the residents at Shedd Aquarium.

For photos, where to stay, ratings, and other tourist information, read our Chicago road trip site .

Getting from Branson to Chicago by flight takes about 4.5 hours. Other options: do a combination of car and flight; or drive. In April, Chicago is slightly colder than Branson - with highs of 59°F and lows of 40°F. Wrap up your sightseeing on the 27th (Sat) to allow time to travel back home.

Things to do in Chicago

Museums Childrens Museums Parks

Side Trip

Ernest Hemingway Birthplace
Highlights from your plan
Museum of Science and Industry ©
Museum of Science and Industry
The Art Institute of Chicago ©
The Art Institute of Chicago
Field Museum ©
Field Museum

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