8 days in Southeast Missouri Itinerary

Start off your visit on the 26th (Sat): contemplate the waterfront views at Current River and then stroll around Missouri Down Under. Keep things going the next day: explore the striking landscape of Alley Spring Grist Mill Historic Site.

To see photos, more things to do, reviews, and other tourist information, you can read our Van Buren road trip planner.

Atlanta to Van Buren is an approximately 8-hour car ride. You can also drive. The time zone changes from Eastern Standard Time to Central Standard Time, which is usually a -1 hour difference. Plan for slightly colder temperatures traveling from Atlanta in November, with highs in Van Buren at 58°F and lows at 37°F. Finish up your sightseeing early on the 27th (Sun) so you can go by car to Rolla.

Kick off your visit on the 28th (Mon): delve into the lush surroundings at Mark Twain National Forest.

To see traveler tips, other places to visit, ratings, and tourist information, use the Rolla trip planner.

Traveling by car from Van Buren to Rolla takes 2.5 hours. November in Rolla sees daily highs of 56°F and lows of 35°F at night. Finish up your sightseeing early on the 28th (Mon) so you can go by car to Arcadia.

Start off your visit on the 29th (Tue): immerse yourself in nature at Taum Sauk Mountain State Park and then appreciate the views at Arcadia Valley.

You can plan Arcadia trip in no time by asking Inspirock to help create your itinerary.

Explore your travel options from Rolla to Arcadia with the Route module. In November in Arcadia, expect temperatures between 55°F during the day and 34°F at night. Finish your sightseeing early on the 29th (Tue) to allow enough time to drive to Sainte Genevieve.

Take a break from the city and head to Pickle Springs Natural Area and Hawn State Park. You'll explore the less-touristy side of things at St. Francois State Park and Bolduc House Museum. Explore the numerous day-trip ideas around Sainte Genevieve: Bonne Terre (The Space Museum & Bonne Terre Mine Tours - West End Diving).

To find more things to do, reviews, ratings, and more tourist information, read Sainte Genevieve tour planning app.

Getting from Arcadia to Sainte Genevieve by car takes about 1.5 hours. In November in Sainte Genevieve, expect temperatures between 54°F during the day and 36°F at night. Wrap up your sightseeing on the 2nd (Fri) to allow time to drive to Cape Girardeau.

Kick off your visit on the 3rd (Sat): trek along Trail of Tears and then look for all kinds of wild species at Cape Girardeau Conservation Nature Center.

To find more things to do, traveler tips, maps, and more tourist information, go to the Cape Girardeau trip planner.

Drive from Sainte Genevieve to Cape Girardeau in 1.5 hours. In December in Cape Girardeau, expect temperatures between 47°F during the day and 30°F at night. Finish your sightseeing early on the 3rd (Sat) to allow enough time to drive back home.