8 days in United States Itinerary

Start off your visit on the 16th (Thu): take in the architecture and atmosphere at Cathedral Basilica of Saint Louis, then take in panoramic vistas at The Gateway Arch, and then see the interesting displays at City Museum. On the 17th (Fri), you'll have a packed day of sightseeing: get a sense of history and politics at Old Courthouse, then test your problem-solving skills at popular escape rooms, and then identify plant and animal life at The Sophia M. Sachs Butterfly House.

To find maps, ratings, traveler tips, and other tourist information, read Saint Louis trip planner.

Jacksonville to Saint Louis is an approximately 3.5-hour flight. You can also drive; or take a bus. Traveling from Jacksonville to Saint Louis, you'll gain 1 hour due to the time zone difference. Prepare for cooler weather when traveling from Jacksonville in February: high temperatures in Saint Louis hover around 45°F and lows are around 26°F. Wrap up your sightseeing on the 17th (Fri) to allow time to fly to Pigeon Forge.

Start off your visit on the 18th (Sat): observe the fascinating underwater world at Ripley's Aquarium of the Smokies, do a tasting at Hillside Winery, then sample the fine beverages at Ole Smoky Tennessee Moonshine, and finally learn about winemaking at Mill Bridge Winery. On the next day, sample the fine beverages at Ole Smoky Whiskey Barrelhouse, do a tasting at Tennessee Homemade Wines, then sample the fine beverages at Ole Smoky, then brush up on your knowledge of spirits at Sugarlands Distilling Company, and finally learn about winemaking at Tennessee Cider Company.

To see more things to do, maps, where to stay, and tourist information, use the Pigeon Forge trip planner.

Traveling by flight from Saint Louis to Pigeon Forge takes 6.5 hours. Alternatively, you can drive; or do a combination of bus, shuttle, and taxi. The time zone changes from Central Standard Time to Eastern Standard Time, which is usually a 1 hour difference. Prepare for somewhat warmer weather when traveling from Saint Louis in February: high temperatures in Pigeon Forge hover around 52°F and lows are around 34°F. Wrap up your sightseeing on the 19th (Sun) to allow time to drive to Hendersonville.

Kick off your visit on the 20th (Mon): look for all kinds of wild species at DuPont State Recreational Forest, indulge your thirst for a good beer at Bold Rock Hard Cider, then sample the tasty concoctions at Sierra Nevada Brewing Co. Tours & Tastings, and finally discover the riches below the earth's surface at Elijah Mountain Gem Mine and Goat Farm.

To find traveler tips, ratings, maps, and other tourist information, read Hendersonville trip maker app.

You can drive from Pigeon Forge to Hendersonville in 2.5 hours. In February in Hendersonville, expect temperatures between 53°F during the day and 31°F at night. Wrap up your sightseeing on the 20th (Mon) early enough to travel to Greenville.

Start off your visit on the 21st (Tue): stroll around River Park North, don't miss a visit to East Carolina University, and then indulge your thirst for a good beer at Uptown Brewing Company.

To see maps, where to stay, reviews, and tourist information, refer to the Greenville travel itinerary planner.

Use the Route module to find suitable travel options from Hendersonville to Greenville. In February, daytime highs in Greenville are 56°F, while nighttime lows are 35°F. Finish up your sightseeing early on the 21st (Tue) so you can go by car to Charleston.

Kick off your visit on the 22nd (Wed): contemplate the long history of Nathaniel Russell House, then hit the best photo ops around with an inspiring photography tour, then head outdoors with Outdoor Activities, and finally walk around Joe Riley Waterfront Park. Get ready for a full day of sightseeing on the next day: go on a hair-raising tour with a ghost and vampire tour, then don't miss a visit to Charleston Fire Department, Station 2/3, then contemplate the long history of Fort Sumter National Monument, and finally get up close to creatures of the deep with a dolphin and whale watching tour.

For maps, where to stay, more things to do, and other tourist information, read our Charleston journey planning site.

Drive from Greenville to Charleston in 5 hours. In February, Charleston is a bit warmer than Greenville - with highs of 63°F and lows of 44°F. Wrap up your sightseeing on the 23rd (Thu) to allow time to drive back home.